MCA_05713_1

Protein

Length

490 amino acids

RNA-seq: read pairs 94, FPKM 2.4, percentile rank 12.5% (100% = highest expression)

Protein function

EGGNOG:	0PJ3T	FG06336.1	mono-carboxylate
SGD closest match:	S000005479	MCH4	Probable transporter MCH4
CGD closest match:	CAL0000177667	orf19.6263	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
A0A0J9XH20_GEOCN	43.87%	506	7e-134	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases OS=Geotrichum candidum GN=BN980_GECA17s00593g PE=4 SV=1
UniRef50_A0A0J9XH20	43.87%	506	1e-130	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XH20_GEOCN
MIA_03436_1	42.77%	491	1e-129	MIA_03436_1
A0A060TFW4_BLAAD	41.54%	467	2e-120	ARAD1D17842p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17842g PE=4 SV=1
Q6CEH9_YARLI	35.92%	348	9e-53	YALI0B15488p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15488g PE=4 SV=1
A0A167D661_9ASCO	28.90%	481	2e-45	Mch4p OS=Sugiyamaella lignohabitans GN=MCH4 PE=4 SV=1
A0A1E3PDP2_9ASCO	27.85%	456	1e-40	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84190 PE=4 SV=1
A0A1E4TLK5_9ASCO	26.49%	502	2e-36	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1237 PE=4 SV=1
MCH4_YEAST	26.89%	450	3e-34	Probable transporter MCH4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCH4 PE=1 SV=1
Q5AAP8_CANAL	26.00%	427	2e-32	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6263 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1671

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
33 - 490
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 490

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  51 - 440
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  299 - 490
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  281 - 479
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  33 - 234
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  45 - 479
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

107 - 112

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

414 - 424

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

223 - 299

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

354 - 364

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 44

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

479 - 490

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

159 - 169

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

286 - 486

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

29 - 280

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

323 - 333

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

132 - 136

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

384 - 388

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

445 - 455

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

191 - 201

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

67 - 85

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

136 - 158

TMHMM
TMhelix (TMhelix)

300 - 319

TMHMM
TMhelix (TMhelix)

82 - 104

TMHMM
TMhelix (TMhelix)

109 - 131

TMHMM
TMhelix (TMhelix)

45 - 67

TMHMM
TMhelix (TMhelix)

363 - 380

TMHMM
TMhelix (TMhelix)

200 - 222

TMHMM
TMhelix (TMhelix)

390 - 412

TMHMM
TMhelix (TMhelix)

457 - 479

TMHMM
TMhelix (TMhelix)

334 - 356

TMHMM
TMhelix (TMhelix)

425 - 447

TMHMM
TMhelix (TMhelix)

171 - 190

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

202 - 222

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

170 - 190

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

300 - 322

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

365 - 383

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

389 - 413

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

137 - 158

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

425 - 444

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

334 - 353

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

86 - 106

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

45 - 66

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

456 - 478

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

113 - 131

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

18 - 37

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

58T

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

61I

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

62V

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

63N

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

65Y

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

66G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

88G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

91Q

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

92P

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

95V

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

99S

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

100V

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

102A

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

103V

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

150L

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

151G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

154V

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

155F

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

158F

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

159A

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

162Q

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

173F

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

174G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

177S

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

178S

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

184G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

311Y

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

314L

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

315Y

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

318L

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

319F

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

322P

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

335V

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

339L

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

343N

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

346S

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

350R

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

398G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

401S

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

402G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

405F

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

409P

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

410A

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

413G

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

424R

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

425L

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

428Y

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

429F

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

432S

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

433A

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

436C

putative substrate translocation pore
58T, 61I, 62V, 63N, 65Y, 66G, 88G, 91Q, 92P, 95V, 99S, 100V, 102A, 103V, 150L, 151G, 154V, 155F, 158F, 159A, 162Q, 173F, 174G, 177S, 178S, 184G, 311Y, 314L, 315Y, 318L, 319F, 322P, 335V, 339L, 343N, 346S, 350R, 398G, 401S, 402G, 405F, 409P, 410A, 413G, 424R, 425L, 428Y, 429F, 432S, 433A, 436C
CDD
cd06174 (MFS)

Protein sequence

>MCA_05713_1
MSTQNDEINRTSLSLDLNNTDFSENEDQGVGERDKDEFPEGGRGWLVIAGTFILLAQTFGIVNVYGQYQIYYEKIFPTVR
LSILSLIGSLQPCIVNLSSVLAVVMFVKYGPRFCLFFATCIVVFGFMMLSLCKEVWQIFLAQGVVIGFGLGFMVFVGFAM
PQQWFKRKRAFAFGLTSSGASIGGLVWPIAFTHLNEKVGFGWTNRIIGFIYIPLLTFAIFAVKSRISISSQQKEIEKSPV
VDVEKEQVKGGSNNDAKKTDNTEQLTEKTFENAPPEIKKKFGIFHKNFILEWEVTKDARFCLLMLANFLVYFGLYPPLFF
MPSYCEKINAPENVVNYILAISNAASIFGRIVPGMIGDRIGRLNTLIPCTLFAGTAILVFWLPSESVPMVIIFGVFYGMA
SGSIFSLYPAVIGQLFGIKGLASRLTLYFFVSAAPCLAGPSIAGQFLPLNAVGTEGFWKLMVFCSVVYMASGLCLIYLRF
TISKKLLVFV

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features