MIA_03436_1

Protein

Length

546 amino acids

Browser: contig04:1195790-1197431-

Protein function

EGGNOG:	0PJ3T	FG06336.1	mono-carboxylate
SGD closest match:	S000005479	MCH4	Probable transporter MCH4
CGD closest match:	CAL0000180528	orf19.2751	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_02679_1	53.915%	562	3.64e-174	MCA_02679_1
A0A0J9XH20_GEOCN	47.239%	489	2.59e-125	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases OS=Geotrichum candidum GN=BN980_GECA17s00593g PE=4 SV=1
UniRef50_A0A0J9XH20	47.239%	489	5.31e-122	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XH20_GEOCN
A0A060TFW4_BLAAD	49.479%	192	7.63e-56	ARAD1D17842p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17842g PE=4 SV=1
Q6CEH9_YARLI	43.933%	239	2.07e-49	YALI0B15488p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15488g PE=4 SV=1
A0A1E3PKI5_9ASCO	28.362%	409	7.59e-30	MFS general substrate transporter (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83425 PE=4 SV=1
A0A1D8PLJ9_CANAL	23.434%	495	1.04e-17	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2751 PE=4 SV=1
A0A167E6V0_9ASCO	36.628%	172	4.29e-18	Mch5p OS=Sugiyamaella lignohabitans GN=MCH5 PE=4 SV=1
MCH4_YEAST	30.500%	200	2.95e-14	Probable transporter MCH4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCH4 PE=1 SV=1
A0A1E4TLK5_9ASCO	32.544%	169	2.38e-14	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1237 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0150

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
56 - 546
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 500 546

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  78 - 385
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  348 - 546
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  330 - 535
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  56 - 257
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  70 - 535
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

184 - 194

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

463 - 473

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

406 - 411

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

132 - 137

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

539 - 546

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 69

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

248 - 348

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

340 - 538

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

48 - 284

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

375 - 385

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

157 - 161

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

434 - 438

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

497 - 515

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

216 - 226

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

91 - 109

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

412 - 434

TMHMM
TMhelix (TMhelix)

71 - 93

TMHMM
TMhelix (TMhelix)

137 - 156

TMHMM
TMhelix (TMhelix)

516 - 538

TMHMM
TMhelix (TMhelix)

439 - 461

TMHMM
TMhelix (TMhelix)

474 - 496

TMHMM
TMhelix (TMhelix)

108 - 130

TMHMM
TMhelix (TMhelix)

195 - 217

TMHMM
TMhelix (TMhelix)

227 - 249

TMHMM
TMhelix (TMhelix)

349 - 371

TMHMM
TMhelix (TMhelix)

386 - 405

TMHMM
TMhelix (TMhelix)

160 - 182

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

439 - 462

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

110 - 131

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

474 - 496

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

138 - 156

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

195 - 215

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

70 - 90

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

227 - 247

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

386 - 405

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

162 - 183

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

412 - 433

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

516 - 538

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

349 - 374

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

83S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

86M

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

87S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

88S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

90Y

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

91G

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

113G

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

116Q

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

117P

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

120I

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

124A

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

125I

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

127S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

128T

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

175S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

176S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

179V

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

180F

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

183Y

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

184T

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

187Q

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

198I

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

199G

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

202A

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

203S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

209G

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

360F

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

363L

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

364F

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

367L

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

368F

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

371V

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

384E

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

388M

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

392N

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

395S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

399R

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

447G

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

450S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

451G

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

454V

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

458P

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

459A

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

462G

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

473R

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

474L

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

477F

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

478F

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

481C

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

482S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

485S

putative substrate translocation pore
83S, 86M, 87S, 88S, 90Y, 91G, 113G, 116Q, 117P, 120I, 124A, 125I, 127S, 128T, 175S, 176S, 179V, 180F, 183Y, 184T, 187Q, 198I, 199G, 202A, 203S, 209G, 360F, 363L, 364F, 367L, 368F, 371V, 384E, 388M, 392N, 395S, 399R, 447G, 450S, 451G, 454V, 458P, 459A, 462G, 473R, 474L, 477F, 478F, 481C, 482S, 485S
CDD
cd06174 (MFS)

Protein sequence

>MIA_03436_1
MDSQNVPTHQAHLDQNMEAPAITNTTAPSEKSSGSMLPQIPLAETATVTTTNTRNAEKDTEEFPEGGRGWLVVAGTFVLM
GASFGMSSIYGQYQRHYLEAFPTTKQSILILIGSLQPFLIYFFAIPSTIFIKRVGPHIAVATSGFILIFSLMMTSLCRQV
WQYALAQGVLFGIGSSISVFVSYTMPQQWFKKKRATAIGIVASGSSVGGLLWPLALYNLTEQVGFDWANRIMGFIFIPLM
AFATFAVKSREHLIGQNTNNIQQEEPQEEAFFVEYSEPNEEHSVCAQDDLQQETGDKSASEHLENLDNQDNFSSNSSSSC
FIREKHWLRQNVFHSGFLVDWSVLKDYHYALIVLGNFVGFFGLFNPLFFIVTYSEVLGIDPNIEKYIMTITNSGSVLGRI
LPGIIGDKIGRLNMLIMAVLSSGLVVLCLWLPSRNTATVFAAGFGYGMTSGALVSLAPAALGQLFGYHGLQSRLSIFFLA
CSFGSLIGPVIGSSFLPNAEDSYVDGKGSLQGYNKLIIFTGVVLLASAAVLTFVRFSINRKVFAFV

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features