Protein

MIA_06422_1

Length
1,140 amino acids

Browser: contig13:7847-11307+

Protein function

EGGNOG:0QDZFReverse transcriptase (RNA-dependent DNA polymerase)
CGD closest match:CAL0000185137orf19.2669Uncharacterized protein

Protein alignments

%idAln lengthE-value
UniRef50_A5DXY548.104%5011.88e-145Uncharacterized protein n=2 Tax=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) TaxID=379508 RepID=A5DXY5_LODEL
MCA_01665_139.315%4961.30e-101MCA_01665_1
A0A161HJI4_9ASCO29.293%4959.32e-58Gag-pol fusion protein OS=Sugiyamaella lignohabitans GN=AWJ20_4398 PE=4 SV=1
YCH4_YEAST38.380%2841.74e-62Putative transposon Ty5-1 protein YCL074W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TY5A PE=5 SV=2
A0A1D8PLS1_CANAL25.893%5607.16e-46Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2669 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3582

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1140

Detailed signature matches

  1. Domain IPR012337
    Ribonuclease H-like domain
    1. SSF53098 (Ribonucle...)
    2. G3DSA:3.30.42...
  2. Domain IPR001584
    Integrase, catalytic core
    1. PF00665 (rve)
    2. PS50994 (INTEGRASE)
  3. Domain IPR013103
    Reverse transcriptase, RNA-dependent DNA polymerase
    1. PF07727 (RVT_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF56672 (DNA/RNA p...)
  2. cd09272 (RNase_HI_R...)
  3. mobidb-lite (disord...)

Residue annotation

  1. active site cd09272
  2. RNA/DNA hybrid bin...

Protein sequence

>MIA_06422_1
MTTRVTVQQAMPKLSKSLSVKPTHFEVVDSHKCDACLGGKATSLPFTGTTEKATRPLELLVSDLSGPHVATPVGHRYVLT
IMDFYSRYSYVELLVKKSDASLAIRNYIARCESYFSGDSRGNRVSYFHSDNGGEYISKDLEQFFVSKGIKHTFTVPHTPQ
QNGVAERLNRTLFEKAKSMLLYSHAPDYLWGEAVKCANYLRNRLPSRTTGGVCPLQLWTGKPPSYQHMRVFGCRANVVIA
DAKRESKLSSNIDPGVFVGYSLDRTAYRVLVDSSIVEARDVYFDESQFPFMKSDKELSSNASGIAFGIGCGSGSMSGPRV
DCNDSGTGSSVGLNSIAGSNSSSGSSFGSRRSLPDVTSVSGSGSSASSTSGFTGSSPSPSLSSSPRSSSSLVVHKPRSVR
RILPSSSAPLESPTLPSLPSSPILPSSDQDPSVSSPIGPSQSDLSQVGSPVVNLITRVILGFRNEGVISGFTRIPPSVEL
EIVPLDQEPPSSDLVKSLDQAGVSVDTKDDTQAILPKSRSRVVAVRLPSVTPAKRPSSHDFVAPPSKHRCDDSAKQPASS
VVPAKRRAEQESISYRRLKSLRFEYDDVALLVFTDPTTFEQAMSSEDAEFWLEACVVEMSSLKRNRTWDLVDLPPGRKAI
NSKWVFKIKRKADGSIERYKARLVCIGFSQVEGIDYTETFAPVVRYETVRIVLAIAAQFGFQVHHMDVETAFLNGDLKED
IYMRQPKGFIVKGQESKVCHLNKSLYGLKQAPLCWNEKIHGALVKLGFVRNESDYGVYTKGRGSAMVIIALYVDDLLIAG
NSTQAIANTKSSLSSMFKMKDLGLVEQFLGMRVKQSPYHITVDVCRYIVDMLEEFGMQNCSSVKTPLPTRDLSDFSESDA
AADPSLYRSIIGKLIYAANCARPDLAVAVSFLCRYMQNPKSMHMEAAKHTLRYLKGSAQLGLEYRAQKVYKLVGYSDADY
AQDKQDRKSFTGYVFILSGGPITWACRKQVSPASSSVESEYMSLSDASKECFWINQLLSLCQIPVPLPVTMFEDNQGCIA
LAQNPVFHRRTKHIDVRYHVVRHYIRSGVIHLEYLDTQVMLADMFTKNLGRVKFETLRGLLGMKAVGDSATRGGVEHAML
SQTSACENCWEIMVDGLCLF

GO term prediction

Biological Process

GO:0015074 DNA integration

Molecular Function

GO:0003676 nucleic acid binding

Cellular Component

None predicted.