Protein

MIA_06413_1

Length
1,653 amino acids

Browser: contig12:52-5378-

Protein function

EGGNOG:0QDZFReverse transcriptase (RNA-dependent DNA polymerase)
CGD closest match:CAL0000185137orf19.2669Uncharacterized protein

Protein alignments

%idAln lengthE-value
UniRef50_A5DXY547.894%4516.74e-125Uncharacterized protein n=2 Tax=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) TaxID=379508 RepID=A5DXY5_LODEL
MCA_01665_139.414%4447.13e-88MCA_01665_1
YCH4_YEAST38.380%2841.68e-61Putative transposon Ty5-1 protein YCL074W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TY5A PE=5 SV=2
A0A161HJI4_9ASCO30.709%3814.43e-55Gag-pol fusion protein OS=Sugiyamaella lignohabitans GN=AWJ20_4398 PE=4 SV=1
A0A1D8PLS1_CANAL25.646%5038.27e-39Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2669 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1036
Predicted cleavage: 15

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1653

Detailed signature matches

  1. Domain IPR025724
    GAG-pre-integrase domain
    1. PF13976 (gag_pre-in...)
  2. Domain IPR012337
    Ribonuclease H-like domain
    1. SSF53098 (Ribonucle...)
    2. G3DSA:3.30.42...
  3. Domain IPR001584
    Integrase, catalytic core
    1. PF00665 (rve)
    2. PS50994 (INTEGRASE)
  4. Domain IPR013103
    Reverse transcriptase, RNA-dependent DNA polymerase
    1. PF07727 (RVT_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. SSF56672 (DNA/RNA p...)
  5. TRANSMEMBRANE (Tran...)
  6. cd09272 (RNase_HI_R...)
  7. mobidb-lite (disord...)

Residue annotation

  1. RNA/DNA hybrid bin...

Protein sequence

>MIA_06413_1
MTTRVTVQQVMGRTSAYINLTSSEKLNPLNYHAWATKILLGLRAMNNGVHLYVEAGTVSPGPNESLDDLTASLDTVVHDV
ILNNISPELIEQVNDVAIRGRDLWLYLHQEYSQLQPADVISLMKSLYAVNIESGPKLVSSIRTHVATWRSIYQSLSPDSV
VAFNILASMSPNCERLIQYALEHRFDGNNADNLDINNFVRNADKWAKLLKLTDDRPRLFRPKPSLPHRRDTVIDLETIWD
EAQAAQQDKDKDDKESKDGKSSRAWFAEAVDGFTQIVDDDSFVSYAFESKTSDVCEKFGIDCSESDDDSESELFDSSEPY
NGDEDYFDYQVSESCSNSELDVVPAADPFLGCTEDPCFVPNHALVRVMILVILNHLLVPYYFIFVDPSPCDIICLADPAV
DPCSSVVDSLVDSVVEPFPSDVTSLADPVVDSCSFDIDSMADPIVDPSSSVTHPTDTKKSRLSPLLYLFSVHQAFVAESA
ASAEAHLVVGPDTFDFIHDTGATSHICNNISYFTNLRPTSTTIRGLGSSSAKAVGDIVVDVLGQDGNPFDRVVLRDVLYV
PNIPRNLFAARRAIAGGCQFIENLDHISAVENGTTRVHAIAMGDLYFCRFRVVLPSKPVHEVFAIEPSANLWHQRLGHAS
VEVLKKLSKSLSVKPTHFEVVDSHKCDACLGGKATSLPFTGTTEKATRPLELLVSDLSGPHVATPVGHRYVLTIMDFYSR
YSYVELLVKKSDASLAIRNYIARCESYFSGDSRGNHLEQFFVSKGIKHTFTVPHTPQQNGVAERLNRTLFEKAKSMLLYS
HAPDYLNRLPSRTTGGVCPLQLWTGKPPSYQHMRVFGCRANVVIADAKRESKLSSNIDPGVFVGYSLDRTAYRVLVDSSI
VEARDVYFDESQFPFMKSDKELSSNASGIAFGIGCGSGSMSGPRADCNDSVRVLVLGLVGLYRTSLLFLVLVLVRLAHLV
LLVPRRLRRCLSSPRSSSSLVVHKPRSVRRILPSSSAPLESPTLPSLPSSPILPSSDQDPSVSSPIGPSQSDLLQVGSPA
GESDNSGDSGISQRGGDIGFHPDVIASSPSPPSVELEIVPLDQEPPSSDLVKSLDQAGVSVDTKDDTQAILPKSRSRVIA
VRLPSVTPAKRPSSHDFVAPPSKHRCDDSAKQAASSVVPAKRRAEQESISYRRLKSLRFEYDDVALLVFTDPTTFEQAIC
VLEMSSLNRNRTWDLVDLPPGRKAINSKWVFKIKRKADGSIERYKARLVCIGFSQVEGIDYTETFAPVVRYETVRIVLAI
AAQFGFQVHHMDVETAFLNGDLKEDIYMRQPKGFIVKGQESKVCHLNKSLYGLKQAPLCWNEKIHGALVKLGFVRNESDY
GVYTKGRGSAMVIIALYVDDLLIAGSSTHAIANTKSSLSSMFKMKDLGLVEQFLGMRVKQSPYHITVDVCRYIVDMLEEF
GMQNCSSVKTPLPTRDLSDFSESDAAADPSLYRSIIGKLIYAANCARPDLAVAVSFLCRYMQNPKSMHMEAAKHTLRYLK
GSAQLGLEYRAQKVYKLVGYSDADYAQDKQDRKSFTGYVFILSGGPITWACRKQVSPASSSVESEYMSLSDASKECFWIN
QLLSLCQIPVPLPVTMFEDNQGCIALAQNPVFHRPHQHIDVRYHVVRTIFAVE

GO term prediction

Biological Process

GO:0015074 DNA integration

Molecular Function

GO:0003676 nucleic acid binding

Cellular Component

None predicted.