Protein

MIA_06406_1

Length
192 amino acids


Browser: contig11:369215-370221+

Protein function

EGGNOG:0PIRJRAC1cell division control protein 42
SGD closest match:S000004219CDC42Cell division control protein 42
CGD closest match:CAL0000192612CDC42Cell division control protein 42 homolog

Protein alignments

%idAln lengthE-value
MCA_06283_196.111%1802.52e-132MCA_06283_1
A0A0J9XAH6_GEOCN90.104%1923.77e-127Similar to Saccharomyces cerevisiae YLR229C CDC42 Small rho-like GTPase OS=Geotrichum candidum GN=BN980_GECA07s00087g PE=3 SV=1
F2Z658_YARLI85.938%1921.35e-122YALI0E25845p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E25845g PE=3 SV=1
A0A167F9W5_9ASCO87.709%1795.89e-122Rho family GTPase CDC42 OS=Sugiyamaella lignohabitans GN=CDC42 PE=3 SV=1
A0A060TBT1_BLAAD85.417%1925.14e-122ARAD1D34452p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D34452g PE=3 SV=1
A0A1E3PDI1_9ASCO84.916%1791.42e-117Structural basis of promiscuous guanine nucleotide exchange By the T-cell essential Vav1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84150 PE=3 SV=1
UniRef50_P6300080.208%1923.94e-110Ras-related C3 botulinum toxin substrate 1 n=1427 Tax=Opisthokonta TaxID=33154 RepID=RAC1_HUMAN
A0A1E4TBM5_9ASCO75.393%1911.59e-108Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_53613 PE=3 SV=1
CDC42_CANAL67.598%1792.89e-92Cell division control protein 42 homolog OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC42 PE=3 SV=1
CDC42_YEAST67.039%1792.46e-92Cell division control protein 42 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC42 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1080

Protein family membership

Domains and repeats

1 20 40 60 80 100 120 140 160 180 192

Detailed signature matches

    1. PF00071 (Ras)
    1. PS51420 (RHO)
    1. SSF52540 (P-loop co...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00449 (RASTRNSFRMNG)
  2. SM00173 (ras_sub_4)
  3. SM00174 (rho_sub_3)
  4. SM00175 (rab_sub_5)
  5. SM00176 (ran_sub_2)
  6. cd01871 (Rac1_like)

Residue annotation

  1. GEF (guanine nucle...
  2. G1 box cd01871
  3. GTP/Mg2+ binding s...
  4. p67PhoxTPR effecto...
  5. Switch I region cd...
  6. GAP (GTPase-activa...
  7. G2 box cd01871
  8. Arfaptin/Por effec...
  9. GDI (guanine nucle...
  10. G3 box cd01871
  11. Switch II region c...
  12. G4 box cd01871
  13. G5 box cd01871

Protein sequence

>MIA_06406_1
MRSIKCVVTGDGAVGKTCMLISYTTNAFPGEYIPTVFDNYSANVMVDNKPINLGLWDTAGQEDYDRLRPLSYPQTGVFLI
CFSLVSPSSFENVKTKWFPEVTHHAPDTPIILVGTKLDLREDRETLEKLKEKRQAPITYAQGVQCAKEIGAVKYLECSAL
TQKGLKAVFDEAIHVALTPQLPKKKKKKCLIV

GO term prediction

Biological Process

GO:0007264 small GTPase mediated signal transduction

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0005622 intracellular