Protein

MIA_06354_1

Length
561 amino acids

Browser: contig11:173133-174819-

Protein function

EGGNOG:0PFF1PGUG_05629Asparaginyl-tRNA synthetase
SGD closest match:S000001061DED81Asparagine--tRNA ligase, cytoplasmic
CGD closest match:CAL0000197236DED81Asparagine--tRNA ligase

Protein alignments

%idAln lengthE-value
MCA_05843_180.179%5600.0MCA_05843_1
A0A0J9XDT3_GEOCN76.148%5660.0Similar to Saccharomyces cerevisiae YHR019C DEB81 Cytosolic asparaginyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA11s01099g PE=4 SV=1
A0A167BXP5_9ASCO74.382%5660.0Asparagine--tRNA ligase DED81 OS=Sugiyamaella lignohabitans GN=DED81 PE=4 SV=1
A0A1E3PER5_9ASCO68.142%5650.0Asparaginyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52791 PE=4 SV=1
A0A060TCI7_BLAAD70.018%5670.0ARAD1D42702p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42702g PE=4 SV=1
Q6C6Z7_YARLI70.018%5670.0YALI0E05005p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E05005g PE=4 SV=1
UniRef50_A0A109V01667.636%5500.0HGL199Wp n=3 Tax=Ascomycota TaxID=4890 RepID=A0A109V016_9SACH
SYNC_YEAST67.029%5520.0Asparagine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DED81 PE=1 SV=1
Q59R18_CANAL64.610%5510.0Asparagine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DED81 PE=4 SV=1
A0A1E4T9Z8_9ASCO62.316%5440.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57723 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0631

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 561

Detailed signature matches

  1. Family IPR002312
    Aspartyl/Asparaginyl-tRNA synthetase, class IIb
    1. PR01042 (TRNASYNTHASP)
  2. Family IPR004522
    Asparagine-tRNA ligase
    1. TIGR00457
  3. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  4. Domain IPR004365
    OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
    1. PF01336 (tRNA_anti-...)
  5. Domain IPR006195
    Aminoacyl-tRNA synthetase, class II
    1. PS50862 (AA_TRNA_LI...)
  6. Domain IPR004364
    Aminoacyl-tRNA synthetase, class II (D/K/N)
    1. PF00152 (tRNA-synt_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:2.40.50...
  3. G3DSA:3.30.93...
  4. SSF55681 (Class II ...)
  5. cd00776 (AsxRS_core)
  6. cd04323 (AsnRS_cyto...)

Residue annotation

  1. putative dimer int...
  2. putative anticodon...
  3. homodimer interfac...
  4. motif 1 cd00776
  5. motif 2 cd00776
  6. active site cd00776
  7. motif 3 cd00776

Protein sequence

>MIA_06354_1
MSELEKKVAEVTLAEGPTLYVNDATGADEASATGTQDKPYKTPAYALYVAPTASILVFKEDAYEPISPSAFKKAKKGADG
LAKKAEKAKKLEEQQAAREAEEQKKIEASKAIVIEQDKSLPEALKIKIKDATENRGKRIKVSGWIHRFRPQKGMAFIVLR
DGSGLLQAVLSGNLANAYQTSTLTRESTVTLYGVISPVPEGQSAPNGHELAVDYYEIVGLAPSGDEAFSNRIQENADPSI
LLDQRHLTLRGDTLSAVMKVRAGLLRAIRDVYYDEGLTEVTPPCIVQTQVEGGSTLFGFKYYGEDAYLTQSSQLYLETCV
PALGDVYCIQESFRAEKSHTRRHLSEYTHIEAELGFLTFDDMLDHIERVICGTIDKLLADPTTSALIKELNPTFEPPSRP
FMRMKYEDALVWLNEHEIPNEEGEKFKFGDDIAEAAERKMTDTIGVPIFLTQFPVEIKSFYMKKVPGNPTVTESVDVLMP
NVGEITGGSMRIDNTEELLAGFKREGINPEPYYWFIDQRKYGTYPHGGYGLGTERILAWLCNRYTVRECSLYPRFTGRAK
P

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006421 asparaginyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004816 asparagine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm