Protein

MIA_06353_1

Length
761 amino acids

Browser: contig11:170477-172763-

Protein function

EGGNOG:0PH6UFG08539.1Type I phosphodiesterase nucleotide pyrophosphatase family protein
SGD closest match:S000000621NPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1
CGD closest match:CAL0000198423orf19.4409Nucleotide diphosphatase/phosphodiesterase

Protein alignments

%idAln lengthE-value
MCA_01984_153.230%7740.0MCA_01984_1
A0A0J9XGR9_GEOCN49.064%7480.0Similar to Saccharomyces cerevisiae YCR026C NPP1 Nucleotide pyrophosphatase/phosphodiesterase family member OS=Geotrichum candidum GN=BN980_GECA16s00318g PE=4 SV=1
UniRef50_A0A0J9XGR949.064%7480.0Similar to Saccharomyces cerevisiae YCR026C NPP1 Nucleotide pyrophosphatase/phosphodiesterase family member n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XGR9_GEOCN
A0A167CPG1_9ASCO54.604%4672.20e-178Npp1p OS=Sugiyamaella lignohabitans GN=NPP1 PE=4 SV=1
A0A060TA95_BLAAD51.663%5114.22e-178ARAD1B05654p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B05654g PE=4 SV=1
A0A1E3PFT7_9ASCO55.955%4451.54e-176Phosphodiest-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_4351 PE=4 SV=1
Q6C6J4_YARLI51.515%4621.00e-164YALI0E09042p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E09042g PE=4 SV=1
A0A1D8PMG4_CANAL48.148%5131.86e-146Nucleotide diphosphatase/phosphodiesterase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4409 PE=4 SV=1
NPP1_YEAST35.685%4962.67e-82Ectonucleotide pyrophosphatase/phosphodiesterase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPP1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0182

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 761

Detailed signature matches

  1. Family IPR002591
    Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
    1. PF01663 (Phosphodiest)
  2. Domain IPR017850
    Alkaline-phosphatase-like, core domain
    1. SSF53649 (Alkaline ...)
  3. Domain IPR017849
    Alkaline phosphatase-like, alpha/beta/alpha
    1. G3DSA:3.40.72...
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. cd16018 (Enpp)
  6. mobidb-lite (disord...)

Residue annotation

  1. Zn binding site cd...
  2. active site cd16018
  3. substrate binding ...
  4. homodimer interfac...

Protein sequence

>MIA_06353_1
MSKRYSIDEPVLSDDDIEEDIVLGSFHPTERDRDLLRADEEIVNSLQKKSSKFYNNSSHNDHDDEDDDDDDDNNLGGRSS
RFFSGKSLLKKYKKLASESTASKKKVGFASDVVDKPSRNNGRYTKLEDYDSPTAIGDAAEHGNLNDSSDSDDFDSDIEID
IREGLSRAELRKRTRKVHGIVLIFAGFIILWLLYNHSFPFHLGHGGGSGSGAEDGWAPRTITNNGTHDFKPTTIVVSLDG
FHPHYVSESLTPHLHTLMTRGGGAPYMIPSFPSSTFPNHFSMVTGKYPANHGIVGNTFWDDKLKKQFFNTNPSESLERVW
WAAQPVWVTAPLQGVRTAVHMWPGSESEWSEVTTSGLFEYDRYNGSEILENKVYRVFNWLDREIESRPELILTYVPTVDT
AGHKYGISGDGLMEALKQVDSLVGELVSGLASRNLTEIVNLVVVSDHGMAPTSNERLIYLDDLIEVDNIEHIDGWPLIGL
RPKASLNLNNLYENLKQAQSLYGEDKWDVYLREDIPSEWRFGGKSYNNFKNRIAPLWLVPKVGWSFTTKDQMEKLNGVYK
PFGVHGYNNTEILMRALFLAQGPYFAAQEFLRPFENIGLYNIMCWSLGIKPVANDAPEKVRDLLVALPENWTDDVVYPGV
KFSAEILQVNSTYDALFGEGQAAYESQKAAANEQKPDAVEEPDPKPTPDADQGFEEDVMEATEAVKDDFSGDDGDSDDDT
TTGGSALKDWYEYFKGKAQDAKAWVGTKIEHLTGSKGQSDE

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.