Protein

MCA_01984_1

Length
743 amino acids

Browser: contigA:6026840-6029072-

RNA-seq: read pairs 2567, FPKM 42.6, percentile rank 61.8% (100% = highest expression)

Protein function

EGGNOG:0PH6UFG08539.1Type I phosphodiesterase nucleotide pyrophosphatase family protein
SGD closest match:S000000621NPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1
CGD closest match:CAL0000198423orf19.4409Nucleotide diphosphatase/phosphodiesterase

Protein alignments

%idAln lengthE-value
MIA_06353_155.01%7690.0MIA_06353_1
A0A0J9XGR9_GEOCN53.24%7250.0Similar to Saccharomyces cerevisiae YCR026C NPP1 Nucleotide pyrophosphatase/phosphodiesterase family member OS=Geotrichum candidum GN=BN980_GECA16s00318g PE=4 SV=1
UniRef50_A0A0J9XGR953.24%7250.0Similar to Saccharomyces cerevisiae YCR026C NPP1 Nucleotide pyrophosphatase/phosphodiesterase family member n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XGR9_GEOCN
A0A167CPG1_9ASCO44.95%7630.0Npp1p OS=Sugiyamaella lignohabitans GN=NPP1 PE=4 SV=1
A0A060TA95_BLAAD48.17%6290.0ARAD1B05654p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B05654g PE=4 SV=1
A0A1E3PFT7_9ASCO55.48%4383e-172Phosphodiest-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_4351 PE=4 SV=1
Q6C6J4_YARLI51.10%5014e-168YALI0E09042p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E09042g PE=4 SV=1
A0A1D8PMG4_CANAL41.98%6365e-142Nucleotide diphosphatase/phosphodiesterase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4409 PE=4 SV=1
NPP1_YEAST37.89%4462e-84Ectonucleotide pyrophosphatase/phosphodiesterase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPP1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0226

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 743

Detailed signature matches

  1. Family IPR002591
    Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
    1. PF01663 (Phosphodiest)
  2. Domain IPR017850
    Alkaline-phosphatase-like, core domain
    1. SSF53649 (Alkaline ...)
  3. Domain IPR017849
    Alkaline phosphatase-like, alpha/beta/alpha
    1. G3DSA:3.40.72...
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. cd16018 (Enpp)
  6. mobidb-lite (disord...)

Residue annotation

  1. substrate binding ...
  2. Zn binding site cd...
  3. active site cd16018
  4. homodimer interfac...

Protein sequence

>MCA_01984_1
MSNNRYSIDNPILENEDIEEDIVLGSFHPTPQDRDLLRADEAVLDHIQKQGHGSRTSKFFNGKGLLKKYKKLASESSSSR
KKVGFASGTSDPGNKGYSKLDNSSAYTENNSMNENHTDSDSDEYQSDIEIEIQEGLSRSELRKRTRKLHGILLLFICFIG
VWFFYNKVFTHYHIPGNSAIPNRSPKKSIILSNGTHEFHPTTLAISLDGFHPHYVSPELTPNLHMLMTQNSGSPYMIPSF
PSSTFPNHWTMVTGLYPSNHGIIGNTFWDEKLNKQFFNTKPGQSLDRVWWGGQPIWQTASKQGLKTAVHMWPGSEVDWND
DGSFEYDKFNGSEILEKKSKRVFEWLDRSFDQRPELILSYVPNVDSVGHTNGINGKELKETLKYVDRLIGDIINGLDARN
LTDIVNLVVVSDHGMAPTSNDRLIYLDDLVETNNIEHVDGWPLIGLRPFPSLNLQALYKNLKDAQTQFGKGKWDVYLRED
IPEEFHFAGKKFNKYRHRIAPLWLIPKVGYAFTTKEQMKKLNGDYRPHGIHGYNNTEVLMRALFLARGPYFANDFFLPIP
NTGLYNILCDTLGIKPSKNDGPPLSQLLQLLPSNWTDSRSYPDVNFSTELLDVNSTYDYLFGQDDLSSSSVSADLNEIKE
PHDDANMSGSGKLSSIELHKNSSSASTAFEAGTSTLSVSSIPSNTSTVVQPSKTGTSQSSSLWADWYDYIAGKAQKVGSW
VGEKIKQILPNEKNDSQGHNEKF

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.