Protein

MIA_06350_1

Length
489 amino acids

Browser: contig11:166216-167686+

Protein function

EGGNOG:0PI3YSLM5Asparaginyl-tRNA synthetase
SGD closest match:S000000618SLM5Asparagine--tRNA ligase, mitochondrial
CGD closest match:CAL0000182802orf19.6698Asparagine--tRNA ligase

Protein alignments

%idAln lengthE-value
MCA_05845_164.575%4940.0MCA_05845_1
A0A0J9XEU9_GEOCN65.361%4850.0Similar to Saccharomyces cerevisiae YCR024C SLM5 Mitochondrial asparaginyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA11s01088g PE=4 SV=1
A0A167CL17_9ASCO53.992%4764.00e-178Asparagine--tRNA ligase SLM5 OS=Sugiyamaella lignohabitans GN=SLM5 PE=4 SV=1
UniRef50_A0A167CL1753.992%4761.10e-174Asparagine--tRNA ligase SLM5 n=6 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CL17_9ASCO
A0A1E3PEG7_9ASCO51.837%4902.86e-172Asparaginyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52794 PE=4 SV=1
A0A060SZ00_BLAAD49.278%4858.93e-167ARAD1A15752p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A15752g PE=4 SV=1
Q6C700_YARLI47.423%4852.31e-150YALI0E04939p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E04939g PE=4 SV=1
Q59R23_CANAL41.379%4935.90e-122Asparagine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6698 PE=4 SV=1
SYNM_YEAST39.831%4722.18e-119Asparagine--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLM5 PE=1 SV=1
A0A1E4TMF3_9ASCO39.540%4782.83e-110Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147718 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9878
Predicted cleavage: 16

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 489

Detailed signature matches

  1. Family IPR002312
    Aspartyl/Asparaginyl-tRNA synthetase, class IIb
    1. PR01042 (TRNASYNTHASP)
  2. Family IPR004522
    Asparagine-tRNA ligase
    1. TIGR00457
  3. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  4. Domain IPR004365
    OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
    1. PF01336 (tRNA_anti-...)
  5. Domain IPR006195
    Aminoacyl-tRNA synthetase, class II
    1. PS50862 (AA_TRNA_LI...)
  6. Domain IPR004364
    Aminoacyl-tRNA synthetase, class II (D/K/N)
    1. PF00152 (tRNA-synt_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.50...
  2. G3DSA:3.30.93...
  3. SSF55681 (Class II ...)
  4. cd00776 (AsxRS_core)
  5. cd04318 (EcAsnRS_li...)

Residue annotation

  1. putative dimer int...
  2. putative anticodon...
  3. homodimer interfac...
  4. motif 1 cd00776
  5. motif 2 cd00776
  6. active site cd00776
  7. motif 3 cd00776

Protein sequence

>MIA_06350_1
MIRSIRALGRRYASTLPLTNRQFLTAPPPESSRVTLSGWIKSVRKSKNVAFADLSDGTFGVPVSVVLAPEDAKSLLTGAC
IQVSGTVQRAPPKKNGNPAEPVYEIAADKVNLLGPATKDYPLQKKYHTQEFLRSIPEYRWKTNTGAAVLRYRSQAIAFFS
KYFASSGFTQVSSPLITASDCEGGGEVFQLSGGKEGPLFFGNDKKAYLSVSSQLHLEVFAGALSRVWNIAPAFRAEDSDT
NRHLSEFWIVEAEIAFVDEMAQVMDVVENMVRSAVTPLLDEKDVEGQFCARDLLAVKRDPDAKEALRERWEMLAGSPEAW
PRVSYTEALDILAKEYARDPTCFGGPANPPPQWGDSIASVHEKYLAGIYFKRPVFVTDYPVEQKPFYMLLNESEAGRQTV
KCFDLLIPDIGELVGGSMRENDLARLKSAMERKGMDPADLEWYVKLREHGSFPHGGYGMGFERFLAFVTGQENVREVIGF
PRWAGSCVC

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006421 asparaginyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004816 asparagine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm