Protein

MIA_06286_1

Length
593 amino acids

Browser: contig10:789717-791499-

Protein function

EGGNOG:0PGI7RFA1replication
SGD closest match:S000000065RFA1Replication factor A protein 1
CGD closest match:CAL0000199773RFA1Replication factor A subunit protein

Protein alignments

%idAln lengthE-value
MCA_01192_139.667%6001.13e-138MCA_01192_1
UniRef50_A0A1E3NU6137.088%5773.01e-118Uncharacterized protein n=2 Tax=Phaffomycetaceae TaxID=115784 RepID=A0A1E3NU61_WICAO
A0A0J9X3U7_GEOCN43.409%4404.39e-116Similar to Saccharomyces cerevisiae YAR007C RFA1 Subunit of heterotrimeric Replication Protein A (RPA) OS=Geotrichum candidum GN=BN980_GECA01s05851g PE=4 SV=1
A0A167C4L4_9ASCO39.535%4304.04e-111Replication factor A subunit protein RFA1 OS=Sugiyamaella lignohabitans GN=RFA1 PE=4 SV=1
RFA1_YEAST38.702%4471.40e-104Replication factor A protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFA1 PE=1 SV=1
Q6C5S2_YARLI32.594%5865.18e-102YALI0E15642p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E15642g PE=4 SV=1
A0A1E3PKU4_9ASCO37.986%4371.33e-100Replication factor-a protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24167 PE=4 SV=1
A0A060TDG7_BLAAD30.298%6047.60e-91ARAD1D43714p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D43714g PE=4 SV=1
Q5ACX4_CANAL28.947%6461.56e-90Replication factor A subunit protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RFA1 PE=4 SV=1
A0A1E4TAA8_9ASCO29.630%4323.26e-59Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_15260 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0310
Predicted cleavage: 29

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 593

Detailed signature matches

  1. Family IPR004591
    Replication factor A protein 1
    1. TIGR00617
  2. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  3. Domain IPR031657
    Replication protein A, OB domain
    1. PF16900 (REPA_OB_2)
  4. Domain IPR013955
    Replication factor A, C-terminal
    1. cd04476 (RPA1_DBD_C)
    2. PF08646 (Rep_fac-A_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.50...
  2. cd04474 (RPA1_DBD_A)
  3. cd04475 (RPA1_DBD_B)
  4. mobidb-lite (disord...)

Residue annotation

  1. generic binding su...
  2. DBD-A/DBD-B interf...
  3. ssDNA binding site...
  4. DBD-B/DBD-A interf...
  5. ssDNA binding site...
  6. generic binding su...
  7. generic binding su...
  8. RPA1 DBD-C/RPA2 DB...
  9. trimerization core...
  10. Zinc binding site ...
  11. RPA1 DBD-C/RPA3 in...

Protein sequence

>MIA_06286_1
MSDPQISYGVLSNIISHSNEQGWFAPRGVVLQILKYKRDDKNIRFLLHDGKNSAPGFCTEAPEGLDLSDIENVPNSLIRI
QNYSIRPLKGKYYVLIRSAEYIGKGEFPSEAPTALPVASNSTEIFSFVNDQNKSTKKEDHTVSTDNRYSAPHQKKTSNEL
FTEISALTPFTTKWRICARVEYRSDIRTFKSKTSGNDGSLFNVTFVDKSGEIRATGFNEIVEKYYNMLEPGSVFVIAGAR
INTANKRYSNLKHDYEITLDRNTTIEPADGFSESVPKMIADFTPLDKLPDIESESVINVIGVAHNVYDATSQMSKSGREY
TKRDIILVDKSLFMVRVTLWSETATKFDDSKQGHVVAIKGARVSDFNGKSLSVLASGLVINDPEIDEAYNLQGWYQNGGH
DSNFKWISTSSGDGTFETTEKYLTLQEVTENRLGMSDTPDFFVTMAVVNRILQREPYYPACTQTNCNKKVTQQTNEKWRC
EKCDMEIEKPNYRYVLSVPANDYTDQIWVSCFDETAQVFLGVSANELYEYHHSDEEAYKHVMEDYNHNEYIFRIKARKDF
FNNVERVRYQVVNIHQADFVTESRKLLDNIQEY

GO term prediction

Biological Process

GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination

Molecular Function

GO:0003677 DNA binding

Cellular Component

GO:0005634 nucleus