Protein

MIA_06278_1

Length
374 amino acids

Browser: contig10:771759-772884-

Protein function

EGGNOG:0PNEUTRP1N-(5'-phosphoribosyl)anthranilate isomerase
SGD closest match:S000002414TRP1N-(5'-phosphoribosyl)anthranilate isomerase
CGD closest match:CAL0000186853TRP1N-(5'-phosphoribosyl)anthranilate isomerase

Protein alignments

%idAln lengthE-value
A0A0J9XFT7_GEOCN41.35%3706e-85Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA12s01748g PE=3 SV=1
UniRef50_A0A0J9XFT741.35%3701e-81Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XFT7_GEOCN
MCA_01637_145.96%3595e-84MCA_01637_1
A0A1E3PNB9_9ASCO55.07%2274e-84Phosphoribosylanthranilate isomerase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_14930 PE=3 SV=1
Q1M2R6_BLAAD52.17%2304e-75ARAD1C20658p OS=Blastobotrys adeninivorans GN=atrp1 PE=3 SV=1
F2Z5Z5_YARLI50.00%2324e-69YALI0B07667p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B07667g PE=3 SV=1
A0A167ET59_9ASCO57.65%1705e-56Phosphoribosylanthranilate isomerase TRP1 OS=Sugiyamaella lignohabitans GN=TRP1 PE=3 SV=1
A0A1E4TFJ6_9ASCO41.15%2432e-43Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106605 PE=3 SV=1
TRPF_YEAST41.20%2334e-45N-(5'-phosphoribosyl)anthranilate isomerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRP1 PE=1 SV=2
TRPF_CANAL43.11%2253e-43N-(5'-phosphoribosyl)anthranilate isomerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TRP1 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1493

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 374

Detailed signature matches

  1. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  2. Domain IPR011060
    Ribulose-phosphate binding barrel
    1. SSF51366 (Ribulose-...)
  3. Domain IPR001240
    N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
    1. PF00697 (PRAI)
    2. cd00405 (PRAI)
    3. MF_00135 (PRAI)

Residue annotation

  1. active site cd00405

Protein sequence

>MIA_06278_1
MTRYTEDDIWNVLFDGVGPLEKTYIRSDDVYSTGVLNARVYVSSPMHIPKVRKAINTLIYRPLLLCEIDLNQEMYFDNLA
LADGIICKKSFECGKSIPKFLKDAENKEDIMFKEDEKNIRISFGNQSINLTDASASQALESIENLPPIVKICGLTTVEAA
KEAITAGANMLGMIMVPNRSRSVPHSVAKEISNLVKSHSSQEFHQDKPLTNMSVFEYNSIKLRNSGPYLVGVFRNQPLKD
VLELQQKFNLDYVQLHGDEPIEWAKEIPVPVIKRFTPNTPGFEQCLTPNYYSLALIDSPLGGEGKLVDRTILDEYANLGA
RFIIAGGLNPENVSSVFSTRGVIGVDVSGGVETNGSKDLEKINKFVVNAKSAFN

GO term prediction

Biological Process

GO:0006568 tryptophan metabolic process
GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004640 phosphoribosylanthranilate isomerase activity

Cellular Component

None predicted.