Protein

MIA_06268_1

Length
389 amino acids

Browser: contig10:752903-754073+

Protein function

EGGNOG:0PFYFIPL1serine threonine-protein kinase
SGD closest match:S000006130IPL1Spindle assembly checkpoint kinase
CGD closest match:CAL0000183313IPL1Spindle assembly checkpoint kinase

Protein alignments

%idAln lengthE-value
A0A0J9XJN3_GEOCN61.229%4233.35e-171Similar to Saccharomyces cerevisiae YPL209C IPL1 Aurora kinase subunit of the conserved chromosomal passenger complex CPC OS=Geotrichum candidum GN=BN980_GECA24s00549g PE=3 SV=1
MCA_05614_185.036%2741.71e-169MCA_05614_1
A0A060THZ4_BLAAD76.493%2682.30e-161ARAD1D42064p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42064g PE=3 SV=1
A0A167EH36_9ASCO74.532%2674.99e-159Aurora kinase OS=Sugiyamaella lignohabitans GN=IPL1 PE=3 SV=1
A0A1E3PQL5_9ASCO73.408%2671.87e-151Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_21761 PE=3 SV=1
UniRef50_W1QGR062.290%2973.52e-135Spindle assembly checkpoint kinase n=16 Tax=Eukaryota TaxID=2759 RepID=W1QGR0_OGAPD
A0A1E4TK36_9ASCO68.462%2602.37e-136Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18595 PE=3 SV=1
IPL1_YARLI51.175%3834.53e-130Spindle assembly checkpoint kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=IPL1 PE=3 SV=1
IPL1_YEAST56.391%2668.72e-111Spindle assembly checkpoint kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IPL1 PE=1 SV=1
IPL1_CANAL50.694%2885.44e-102Spindle assembly checkpoint kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=IPL1 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1135

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 389

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. PIRSF000654 (ILK)
  4. cd14007 (STKc_Aurora)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd14007
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MIA_06268_1
MSVSTLETRLSKVSIGEANPDSHSLTQQPLKINSARNHTSASSTATNRSIHGQQPRKNLKIHTSSIRPPSPQRTFNNTTT
YSNSNFAHKSIIRDSGLTKQISLQDSASSTGTASTQTRNFTLNDFEIGRKLGKGKFGKVYCVKDKATGYICALKVMSKKE
LIDYKVEKQFRREIEIQSNLRHPNISRLYGHFDDDQNVYLLIEYVAKGELFKVLRKKGTFNDVRASKYIYQMANALQYLH
NKHVIHRDIKPENILLGLDGNIKISDFGWSVYAPVSRRTTMCGTLDYLPPEMVEAKEHDYRVDVWSLGILTYEFLVGSPP
FEEPGHVATYKRISKVDLKIPETVSPEAADIIKRFLQHSPEKRFPLDKVGEHPWIIKNRPYWNSIEHLG

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.