Protein
MIA_06205_1
Length
90 amino acids
Browser: contig10:561729-562002-
Protein function
EGGNOG: | 0PRY8 | DPH3 | Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L- methionine to a histidine residue. Diphthamide is a post- translational modification of histidine which occurs in elongation factor 2 |
---|---|---|---|
SGD closest match: | S000007587 | KTI11 | Diphthamide biosynthesis protein 3 |
CGD closest match: | CAL0000195342 | KTI11 | Kti11p |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
A0A0J9X4Z0_GEOCN | 80.597% | 67 | 3.87e-37 | Similar to Saccharomyces cerevisiae YBL071W-A KTI11 Zn-ribbon protein that co-purifies with Dph1 and Dph2 in a complex required for synthesis of diphthamide on translation factor eEF2 OS=Geotrichum candidum GN=BN980_GECA02s07292g PE=4 SV=1 |
MCA_03466_1 | 74.286% | 70 | 1.35e-33 | MCA_03466_1 |
A0A060TE89_BLAAD | 72.857% | 70 | 9.47e-33 | ARAD1D49918p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D49918g PE=4 SV=1 |
UniRef50_Q6CMG4 | 73.134% | 67 | 1.25e-27 | Diphthamide biosynthesis protein 3 n=75 Tax=Eukaryota TaxID=2759 RepID=DPH3_KLULA |
DPH3_YEAST | 62.857% | 70 | 1.43e-29 | Diphthamide biosynthesis protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KTI11 PE=1 SV=1 |
A0A1E3PP01_9ASCO | 67.143% | 70 | 6.34e-29 | Zf-CSL-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_57530 PE=4 SV=1 |
DPH3_YARLI | 67.164% | 67 | 2.20e-27 | Diphthamide biosynthesis protein 3 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DPH3 PE=3 SV=1 |
A0A1E4TA65_9ASCO | 73.333% | 60 | 3.93e-27 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29424 PE=4 SV=1 |
A0A1D8PHF7_CANAL | 63.235% | 68 | 1.60e-25 | Kti11p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KTI11 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0018
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
10
20
30
40
50
60
70
80
90
90
Detailed signature matches
Protein sequence
>MIA_06205_1 MSIYDEIEIEDMTFDEDTQLFTYPCPCGDRFQIFIDDLVDGSNNIAVCPSCSLQIEVIFEASDLEKYIKKEDSDAEEADG ITSAPDLICA
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.