MIA_06187_1

Protein

Length

1,959 amino acids

Protein function

EGGNOG:	0PFZJ	KIN1	serine threonine protein kinase
SGD closest match:	S000002529	KIN1	Serine/threonine protein kinase KIN1
CGD closest match:	CAL0000177153	KIN2	Non-specific serine/threonine protein kinase

Protein alignments

	%id	Aln length	E-value
MCA_00992_1	71.52%	453	0.0	MCA_00992_1
A0A0J9XIB4_GEOCN	71.36%	440	0.0	Non-specific serine/threonine protein kinase OS=Geotrichum candidum GN=BN980_GECA16s01583g PE=4 SV=1
UniRef50_A0A0J9XIB4	71.36%	440	0.0	Non-specific serine/threonine protein kinase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIB4_GEOCN
A0A161HLG9_9ASCO	61.68%	475	2e-175	Non-specific serine/threonine protein kinase OS=Sugiyamaella lignohabitans GN=KIN2 PE=4 SV=1
W0TYN3_YARLI	61.54%	442	3e-175	Non-specific serine/threonine protein kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D22770g PE=4 SV=1
A0A060TDK3_BLAAD	61.21%	446	2e-171	Non-specific serine/threonine protein kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D44594g PE=4 SV=1
A0A1E3PRX9_9ASCO	56.95%	453	1e-162	Non-specific serine/threonine protein kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81218 PE=4 SV=1
A0A1D8PRN8_CANAL	54.07%	455	1e-143	Non-specific serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KIN2 PE=4 SV=1
A0A1E4THD0_9ASCO	51.72%	437	1e-135	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20657 PE=3 SV=1
KIN1_YEAST	47.27%	440	6e-121	Serine/threonine protein kinase KIN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIN1 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0137

Protein family membership

None predicted.

Domains and repeats

Domain
685 - 965
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
1,172 - 1,199
Protein kinase-like domain (IPR011009)
1,694 - 1,753
KA1 domain/Ssp2, C-terminal (IPR028375)
1,910 - 1,959
KA1 domain/Ssp2, C-terminal (IPR028375)
Kinase associated domain 1 (KA1) (IPR001772)

1 200 400 600 800 1000 1200 1400 1600 1800 1959

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  685 - 965
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  1,172 - 1,199
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  688 - 964
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. SM00220 (serkin_6)
  
  688 - 964
  
  SMART
  SM00220 (serkin_6)
3. PF00069 (Pkinase)
  
  746 - 964
  
  Pfam
  PF00069 (Pkinase)
IPR028375

KA1 domain/Ssp2, C-terminal
1. SSF103243 (KA1-like)
  
  1,913 - 1,959
  
  SUPERFAMILY
  SSF103243 (KA1-like)
  
  1,694 - 1,753
  
  SUPERFAMILY
  SSF103243 (KA1-like)
IPR001772

Kinase associated domain 1 (KA1)
1. PF02149 (KA1)
  
  1,916 - 1,959
  
  Pfam
  PF02149 (KA1)
2. PS50032 (KA1)
  
  1,910 - 1,959
  
  PROSITE profiles
  PS50032 (KA1)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  694 - 717
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  831 - 843
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

Coil

1,954 - 1,959

COILS
Coil (Coil)

1,143 - 1,166

COILS
Coil (Coil)
G3DSA:1.10.51...

808 - 1,184

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

678 - 807

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
G3DSA:3.30.31...

1,690 - 1,959

GENE3D
G3DSA:3.30.310.80 (G3DSA:3.30.310.80)
cd14077 (STKc_Kin1_2)

686 - 964

CDD
cd14077 (STKc_Kin1_2)
mobidb-lite (disord...)

726 - 755

MobiDB Lite
mobidb-lite (disorder_prediction)

1,378 - 1,496

MobiDB Lite
mobidb-lite (disorder_prediction)

549 - 684

MobiDB Lite
mobidb-lite (disorder_prediction)

1,293 - 1,350

MobiDB Lite
mobidb-lite (disorder_prediction)

1,039 - 1,098

MobiDB Lite
mobidb-lite (disorder_prediction)

1,640 - 1,698

MobiDB Lite
mobidb-lite (disorder_prediction)

1,540 - 1,592

MobiDB Lite
mobidb-lite (disorder_prediction)

226 - 291

MobiDB Lite
mobidb-lite (disorder_prediction)

1,852 - 1,883

MobiDB Lite
mobidb-lite (disorder_prediction)

1,605 - 1,625

MobiDB Lite
mobidb-lite (disorder_prediction)

1,166 - 1,269

MobiDB Lite
mobidb-lite (disorder_prediction)

443 - 514

MobiDB Lite
mobidb-lite (disorder_prediction)

81 - 213

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 35

MobiDB Lite
mobidb-lite (disorder_prediction)

1,756 - 1,800

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

694V

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

695G

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

696A

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

697G

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

702V

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

715A

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

717K

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

773C

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

789F

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

790E

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

791Y

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

792V

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

796Q

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

839E

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

840N

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

842L

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

852I

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)

853D

ATP binding site
694V, 695G, 696A, 697G, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 839E, 840N, 842L, 852I, 853D
CDD
cd14077 (STKc_Kin1_2)
active site cd14077

694V

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

695G

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

696A

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

697G

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

698S

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

702V

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

715A

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

717K

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

773C

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

789F

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

790E

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

791Y

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

792V

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

796Q

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

798L

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

799D

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

801I

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

834R

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

835D

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

837K

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

839E

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

840N

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

842L

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

852I

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

853D

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

856L

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

870C

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

871G

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

872S

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

873L

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

874Y

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

876A

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

906G

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

907K

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

908V

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

909P

active site
694V, 695G, 696A, 697G, 698S, 702V, 715A, 717K, 773C, 789F, 790E, 791Y, 792V, 796Q, 798L, 799D, 801I, 834R, 835D, 837K, 839E, 840N, 842L, 852I, 853D, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)
polypeptide substr...

796Q

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

798L

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

799D

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

801I

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

835D

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

837K

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

839E

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

856L

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

870C

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

871G

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

872S

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

873L

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

874Y

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

876A

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

906G

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

907K

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

908V

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)

909P

polypeptide substrate binding site
796Q, 798L, 799D, 801I, 835D, 837K, 839E, 856L, 870C, 871G, 872S, 873L, 874Y, 876A, 906G, 907K, 908V, 909P
CDD
cd14077 (STKc_Kin1_2)
activation loop (A...

852I

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

853D

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

854F

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

855G

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

856L

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

857S

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

858N

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

859L

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

860Y

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

861S

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

862S

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

863D

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

864H

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

865L

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

866L

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

867R

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

868T

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

869Y

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

870C

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

871G

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

872S

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

873L

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

874Y

activation loop (A-loop)
852I, 853D, 854F, 855G, 856L, 857S, 858N, 859L, 860Y, 861S, 862S, 863D, 864H, 865L, 866L, 867R, 868T, 869Y, 870C, 871G, 872S, 873L, 874Y
CDD
cd14077 (STKc_Kin1_2)

Protein sequence

>MIA_06187_1
MSLSSSPPTALGSQQQQQQEQQRQHKQQHSDKNFQGTFNQSCVAYSSGLEGVNSSLSGCNNNKERFKERLFLDHRALRTT
QETANIPSPALDSPINVASPFDDSNPIEMNTVTQAPKLTSSLSPSSSLSSASSPSRPVSYGSEEGSPTASGKGRKFHGHH
HNSQSQGQNQNYGHGSLPNHAAKHHRSQSYNHGHGICDSLQQPSSSSSFSTSSSFSTGIATTSSLASASDSTAPSSASST
SSHGQHHKTQLHADQIKLPDPASGFRVLGDSNSTLQQVSDGGDNSTGGGVDRSAGGCSSALGSGYARLGNHGNTDNGSYF
GEALLAGSPMAGSLVGSTNANGTTAGNSKSSPAPISVLGGVCKTVDGTAVCGPGEPKVGTPAKCTSHCAGTNTTVPQIAS
AAASQISPTLTSPLSAHINTTPTTANAASATTTATPISTFTTTTTLTSSSSSSPTSPSSSIPTSPLRRYLHIRPPDPVLA
PSTNLKSNLNSHQVTTSISPTSRQTSHSTAASPVAVSSYTVNSNHLNNPLQNKQKQFPLQLSKQQKPLPIQTNKQQSPAE
LQHSSSLDPFRTSTIPPAKQYRHQHSASVPVPPLKSPPSSTSQQANMSASSHPPAQSISATQAQSSSHYRTSSRHSSSNG
VNSNGHATNNGHSNGNTNGNGNTNTANTSSSTTPSQTKVHRRRSIGNWDLIKTVGAGSMGQVKLARNRVTGEYCAVKVVP
RATVEHRRRLQQQAAEGHPPEPQTNNKESDESKDIRTVREAAIGRLLHHKYICQLYEMHVMSSHYYMLFEYVSGGQMLDY
IIAHGSLKEKQARKFSRAIASALDYCHHNSIVHRDLKIENILISQSGDIKIIDFGLSNLYSSDHLLRTYCGSLYFAAPEL
LSAHPYMGPEIDVWSFGVVLYVLVCGKVPFDDQSMPALHAKIKRGFVEYPSTITPDCKDLLSRMLVVDPTNRATLQEVRH
HPWMVKGYDKPPDSHIPNRRPLRLPLDPAVIHDMTGFEFGSEEHITKKLTAILESSRYISACREWYRVRGIDMDSGIPVT
ENNSAAQSSSNHEQARRSRHFSIDFYKRRSLSGDDLNGNSNGEPIGTPIGPMRTQDPTNAYHPLISIYFLVQERQERLRK
AKLEEDFKLSQHLSPQQALSFQQQQQLQQQQQQQQQQQQLQQQQQQPQQLPQQLPQQQPQQFLQPAYQPQPSQQQQQPHT
ASPQIVQAAIASPSLQPQQQQQVPTIQVQDHSATSTSGQQYKEPPQSPPHRQFALQPTSPGAPTPAYNYQPLVPQLQQQQ
HDEKRFLAPSIPAPEAVHTSPPTSYTVSSAYAQSQQSQQGMAPSTSKGRARSRTHGESDSSDKLFIFGGNKNNAAGHTSS
NSGGGGLSFTTNLLRRFSSKRKASREPPQQQPQQQSLLTRPQSRHHHSQSAAPAFNEIRLSEDGSTSPPTNIARTPTAGY
KQQQQQQHPAANVTSPQQSYNPQQQQQQPQNPQQLSRSVSSKPYPKPGYLDPNSYASQSISAATSGGYGTATTTPGNIAI
AASKQGTFTTGSLSRKFHPSARAKSLGHVRHELQQQQGNAPPPRPPRDDLGQVPPVPTVVTSSGTATPADSADIADEFFD
QYYGSNDSDEIGGRNSISNNSSTNQVSNSAAAASATATITSTTTSNTAGIPARSAGAKGSLAPGASIAATGGQALTNQTS
NHSSNHPAPGQPGSMPSIDYPKQVFLKGFFSVQSTSTKPLAYIRSDIIRVLNQLGVEYQEIRGGFSCIHRPSLRDDGNMH
SQQYLAAPGSPAVGGTAHSPPNSPQAGDTPQRGHWRKLSFGSGFFSNRRSRHQNESTNNIFDLSSDLSTDSVSALTNNGL
MITNSSGSNAHIAQPPLSAAGSLGSPQSPSTGGSGGFRSGATNSGNVNGTYNAGGSDLLASTTGAPTSNLSQVRTPLQFE
IWIVLVPILKLHGVQFKKLRGNSWLYKNLATKILSELRL

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component