Protein
MIA_06139_1
Length
446 amino acids
Browser: contig10:355599-357172-
Protein function
| EGGNOG: | 0PIDE | TUB2 | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain |
|---|---|---|---|
| SGD closest match: | S000001857 | TUB2 | Tubulin beta chain |
| CGD closest match: | CAL0000176403 | TUB2 | Tubulin beta chain |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_04907_1 | 92.558% | 430 | 0.0 | MCA_04907_1 |
| A0A1E3PFH7_9ASCO | 84.055% | 439 | 0.0 | Tubulin beta chain OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47457 PE=3 SV=1 |
| TBB1_GEOCN | 86.047% | 430 | 0.0 | Tubulin beta-1 chain OS=Geotrichum candidum PE=3 SV=2 |
| A0A1D8PC97_CANAL | 79.730% | 444 | 0.0 | Tubulin beta chain OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TUB2 PE=3 SV=1 |
| UniRef50_A0A063C9B7 | 81.206% | 431 | 0.0 | Beta-tubulin n=1990 Tax=Eukaryota TaxID=2759 RepID=A0A063C9B7_9HYPO |
| Q6C7H8_YARLI | 80.587% | 443 | 0.0 | Tubulin beta chain OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00726g PE=3 SV=1 |
| A0A060T354_BLAAD | 80.899% | 445 | 0.0 | Tubulin beta chain OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A06952g PE=3 SV=1 |
| TBB_YEAST | 80.137% | 438 | 0.0 | Tubulin beta chain OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TUB2 PE=1 SV=2 |
| A0A1E4TEH0_9ASCO | 75.632% | 435 | 0.0 | Tubulin beta chain (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_60471 PE=3 SV=1 |
| A0A161HF60_9ASCO | 85.632% | 348 | 0.0 | Tubulin beta chain OS=Sugiyamaella lignohabitans GN=TUB2 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0323
Protein family membership
- Tubulin (IPR000217)
- Beta tubulin (IPR002453)
Domains and repeats
-
Domain
-
Domain
-
Domain
1
50
100
150
200
250
300
350
400
446
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
cd02187 (beta_tubulin)
Residue annotation
-
beta/alpha domain ...
-
nucleotide binding...
-
Taxol binding site...
-
alpha/beta domain ...
Protein sequence
>MIA_06139_1 MREIIHLSTGQCGNQIGSAFWQTISDEHGIDPSGNYVGDNPLQLERLNVYYNEASHRKYVPRAVLVDLEPGTMDAVRSGP FGNLFRPDNFVFGQSSAGNNWAKGHYTEGAELVDQVLDVIRREAEGCDSLQGFQVSHSLGGGTGSGMGTLLISKMREEYP DRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENADETFCIDNEALYDICQKTLKLQHPTLLDLNQLVSAVMSGITTCL RFPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLSAASTQSFRALSVPELTQQIFDPKNMMAASDPRHGRYLTVATFFRGK VSVKEVEDQMRQVQQRNADFFVEWIPNNVQTAICSIPPKDAKMSATFVANSTSIQELFKRVGDQFSAMFRRKAFLHWYTN EGMEESEFTEAESNMTDLVSEYQQYQEATVEDDYEYDDEMQLEPEQ
GO term prediction
Biological Process
GO:0007017 microtubule-based process
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Cellular Component
GO:0005874 microtubule