Protein
MCA_04907_1
Length
448 amino acids
Gene name: TUB2A
Description: Tubulin beta chain
Browser: contigC:4387542-4389191+
RNA-seq: read pairs 14278, FPKM 392.9, percentile rank 93.4% (100% = highest expression)
Protein function
Annotation: | TUB2A | Tubulin beta chain | |
---|---|---|---|
KEGG: | K07375 | TUBB | tubulin beta |
EGGNOG: | 0PIDE | TUB2 | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain |
SGD closest match: | S000001857 | TUB2 | Tubulin beta chain |
CGD closest match: | CAL0000176403 | TUB2 | Tubulin beta chain |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_06139_1 | 92.56% | 430 | 0.0 | MIA_06139_1 |
TBB1_GEOCN | 86.05% | 430 | 0.0 | Tubulin beta-1 chain OS=Geotrichum candidum PE=3 SV=2 |
A0A1E3PFH7_9ASCO | 84.65% | 430 | 0.0 | Tubulin beta chain OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47457 PE=3 SV=1 |
A0A1D8PC97_CANAL | 82.33% | 430 | 0.0 | Tubulin beta chain OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TUB2 PE=3 SV=1 |
Q6C7H8_YARLI | 81.63% | 430 | 0.0 | Tubulin beta chain OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00726g PE=3 SV=1 |
A0A060T354_BLAAD | 81.63% | 430 | 0.0 | Tubulin beta chain OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A06952g PE=3 SV=1 |
UniRef50_P68371 | 80.56% | 427 | 0.0 | Tubulin beta-4B chain n=276 Tax=Eukaryota TaxID=2759 RepID=TBB4B_HUMAN |
TBB_YEAST | 80.23% | 430 | 0.0 | Tubulin beta chain OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TUB2 PE=1 SV=2 |
A0A1E4TEH0_9ASCO | 75.58% | 430 | 0.0 | Tubulin beta chain (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_60471 PE=3 SV=1 |
A0A161HF60_9ASCO | 87.07% | 348 | 0.0 | Tubulin beta chain OS=Sugiyamaella lignohabitans GN=TUB2 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0425
Protein family membership
- Tubulin (IPR000217)
- Beta tubulin (IPR002453)
Domains and repeats
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Domain
-
Domain
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Domain
1
50
100
150
200
250
300
350
400
448
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
cd02187 (beta_tubulin)
Residue annotation
-
beta/alpha domain ...
-
nucleotide binding...
-
Taxol binding site...
-
alpha/beta domain ...
Protein sequence
>MCA_04907_1 MREIIHLSAGQCGNQIGSSFWQTISDEHGIDPSGNYVGDNPLQLERLNVYYNEATHGKYVPRAVLVDLEPGTMDAVRGGP FGNLFRPDNFVFGQSSAGNNWAKGHYTEGAELVDNVLDVVRREAEGCDSLQGFQVSHSLGGGTGSGMGTLLISRMREEYP DRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENADETFCIDNEALYDICQKTLKLPQPTLTDLNQLVSAVMSGITTCL RFPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLSASGSKSFRSLTVPELTQQMFDPKNMMAASDPRHGRYLTVASFFRGQ VSVKEVEDQMRIVQEKNAGYFVEWIPNNVQTAICSIPPKDVSMSATFVANSTSIQELFKRVGDQFSAMFRRKAFLHWFTS EGMEESEFTEAESNMADLVSEYQQYQDATIDDEEYEYEDEQLIDQSLQ
GO term prediction
Biological Process
GO:0007017 microtubule-based process
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Cellular Component
GO:0005874 microtubule