Protein

MIA_06123_1

Length
980 amino acids

Browser: contig10:308726-311727-

Protein function

EGGNOG:0PH2KFG10391.1RNA helicase
SGD closest match:S000000815PRP22Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22
CGD closest match:CAL0000186259orf19.5865DEAH-box RNA-dependent ATPase

Protein alignments

%idAln lengthE-value
MCA_06137_180.435%8280.0MCA_06137_1
A0A0J9XIY3_GEOCN75.607%8240.0Similar to Saccharomyces cerevisiae YNR011C PRP2 RNA-dependent ATPase in the DEAH-box family OS=Geotrichum candidum GN=BN980_GECA17s02375g PE=4 SV=1
A0A167FAH5_9ASCO73.792%8280.0DEAH-box RNA-dependent ATPase PRP2 OS=Sugiyamaella lignohabitans GN=PRP2 PE=4 SV=1
A0A060TCL8_BLAAD70.424%8250.0ARAD1D00572p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D00572g PE=4 SV=1
A0A1E3PNS0_9ASCO58.912%9930.0ATP-dependent RNA helicase DHX8 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40141 PE=4 SV=1
Q6C9M4_YARLI64.891%8260.0YALI0D09955p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D09955g PE=4 SV=1
UniRef50_K0KMX365.588%8340.0Pre-mRNA-splicing factor n=68 Tax=Fungi TaxID=4751 RepID=K0KMX3_WICCF
A0A1E4TFZ5_9ASCO55.650%8230.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_108233 PE=4 SV=1
Q5ANN5_CANAL56.977%6880.0DEAH-box RNA-dependent ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5865 PE=4 SV=1
PRP22_YEAST53.249%6310.0Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRP22 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1895

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 980

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  5. Domain IPR007502
    Helicase-associated domain
    1. SM00847 (ha2_5)
    2. PF04408 (HA2)
  6. Domain IPR011709
    Domain of unknown function DUF1605
    1. PF07717 (OB_NTP_bind)
  7. SITE IPR002464
    DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    1. PS00690 (DEAH_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.13...
  3. G3DSA:3.40.50...
  4. cd00046 (DEXDc)
  5. cd00079 (HELICc)
  6. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MIA_06123_1
MSALNYWISDNLQQILGASDDNTIDFCVAAARAAKSATALITTLGDVGLPSTKEAKHFITELFNKVNPGKSTKQEPSRKK
NAAQYELLLDDEQGDELVIKPRKKRRDFSDEEREKPTKKREQTKQRSESPEKSPKKSNKNESLKSKERSKELEEFSELRK
ISRQRYLSAREEQKLELLAKEVEFLEEDIEKYGWDNLSRREQQDYKYKREILEISRERKLSKDAAEEYHLPEDYFTKQGK
IDKKKKESVLYQRYKPVEKSEAAAENEAWEKEQQQRAKVSSRKKQTSEEKYDYVFDQSQHIDFITDHVSKETEEQKLLEK
RIEEERKRIKTIEDTRKSLPVYAHRKGLLEAIKDHQVLIVVGETGSGKTTQLPQYLHEAGYTKNGMKVGCTQPRRVAAMS
VAARVADEMGCRLGGEVGYTIRFEDKSSDKTVIKYMTDGMLLREFLTDPELSSYSAIMIDEAHERTLHTDILFGLLKDIA
KYRPELRLLISSATLNAEKFSKYFDGAPIYNVPGRRFEVDVYYTKQPEANYLHAAITTVFQIHVTQKKGDILVFLTGQDE
IETAAENLADTARKLGKKIPDMIICPIYANLPAELQSKIFEPTPEGARKVVLATNIAETSITIDGIVFVIDPGFVKENVY
NPRSGMESLVVTPCSRASADQRAGRAGRVGPGKCFRLYTKWAFYNELPPNTTPEILRTNLGSVVLLLMSLGINDIMNFDF
LDAPPASALIKALELLYALGALNDRGQLTRLGRQMAEFPTDPMLAKAILASDQYGCVDEVLSIVSMLGEASALFYRPKDK
KLYADQAREAFTQQGGDHLTLLEVWRQWVEADYSYQWAQDNFLQFRSLTRARDVRDQLERLCERVEVEVRSLPEGAHEGT
ELIQKAIASGFFAHTAKMSRSGDSYQVVKTRQTVHIHPSSVLFMHKPKWLLYHELVLTSKEFMRNCMPLRPEWLVEVAPH
YYKQKDLDEMGAIPKKMPRQ

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding

Cellular Component

None predicted.