Protein

MCA_06137_1

Length
1,075 amino acids

Gene name: PRP2

Description: Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

Browser: contigD:3336436-3339735-

RNA-seq: read pairs 1218, FPKM 14.0, percentile rank 32.4% (100% = highest expression)

Protein function

Annotation:PRP2Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2
KEGG:K12813DHX16 pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13]
EGGNOG:0PH2KFG10391.1RNA helicase
SGD closest match:S000005294PRP2Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2
CGD closest match:CAL0000186259orf19.5865DEAH-box RNA-dependent ATPase

Protein alignments

%idAln lengthE-value
MIA_06123_179.81%8370.0MIA_06123_1
A0A0J9XIY3_GEOCN73.33%8400.0Similar to Saccharomyces cerevisiae YNR011C PRP2 RNA-dependent ATPase in the DEAH-box family OS=Geotrichum candidum GN=BN980_GECA17s02375g PE=4 SV=1
A0A060TCL8_BLAAD70.95%8400.0ARAD1D00572p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D00572g PE=4 SV=1
A0A167FAH5_9ASCO70.73%8440.0DEAH-box RNA-dependent ATPase PRP2 OS=Sugiyamaella lignohabitans GN=PRP2 PE=4 SV=1
A0A1E3PNS0_9ASCO66.59%8350.0ATP-dependent RNA helicase DHX8 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40141 PE=4 SV=1
UniRef50_K0KMX363.69%8510.0Pre-mRNA-splicing factor n=68 Tax=Fungi TaxID=4751 RepID=K0KMX3_WICCF
Q6C9M4_YARLI63.22%8510.0YALI0D09955p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D09955g PE=4 SV=1
A0A1E4TFZ5_9ASCO54.92%8340.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_108233 PE=4 SV=1
Q5ANN5_CANAL57.02%6910.0DEAH-box RNA-dependent ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5865 PE=4 SV=1
PRP2_YEAST53.80%7100.0Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRP2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0693

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1075

Detailed signature matches

  1. Domain IPR002483
    PWI domain
    1. PF01480 (PWI)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  4. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  5. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  6. Domain IPR007502
    Helicase-associated domain
    1. SM00847 (ha2_5)
    2. PF04408 (HA2)
  7. Domain IPR011709
    Domain of unknown function DUF1605
    1. PF07717 (OB_NTP_bind)
  8. SITE IPR002464
    DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    1. PS00690 (DEAH_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.13...
  3. G3DSA:3.40.50...
  4. cd00046 (DEXDc)
  5. cd00079 (HELICc)
  6. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MCA_06137_1
MSALNFWISDNLQEILGVSDDNTVDFCIASAKSAKSQSALYSTLNDAGFPSNAQSRSFVNELYKRTHPESLSTSAANKPV
KKTKQVISKYELLLDNEDDENDNRQNSQVPKTKSSNMKKLKKTEFKKSSHSRKRRSVSEDESTSEESEYESESEHGSESS
HGYRRDLEAKSSTLRKPENAKKAEKETDGDDDDERDRRERDELAEKLKLKDSKSEKSKQSEERRKRKEIEDDVENHQEEI
GHLRKAARQRYLNVREGQQLQLLETEVALLEEDIKRYGWEGLSERERQDYKYKKEILDISNERKRSKNENAQEYQLPDDY
FTKQGKIDKRKKESVLYQRYKPTEENQQRKEAEAWEAEQQRRALSLTKGKSKKQNGKDTTTEEEYDYVFDKSQFIDFMED
SKTTAADEDELLARRIEEEKKRIKTIDETRKSLPVYKHRDQLLDAIRENQVLIVVGETGSGKTTQLPQYLYEAGYCKNGM
KVGCTQPRRVAAMSVAARVADEMGTRLGGQVGYTIRFEDKSSEKTVIKYMTDGMLLREFLTDPELSTYSVIMIDEAHERT
LHTDILFGLIKDIAKFRPELRLLISSATLNAQKFSEYFDGAPIYYVPGRRFPVDIHYTKNPEANYLHAAITTVFQIHVTQ
KTGDILVFLTGQEEIEMAAENLAETARKLGKKIPDMIICPIYANLPSELQSKIFEPTPQGARKVVLATNIAETSITIDGI
AFVIDPGYVKENVYNPKTGMESLVVTPCSRASADQRAGRAGRVGPGKCFRLYTKWAFYNELPANTTPEILRTNLGSVVLL
LMSLGINDILNFDFLDSPPSDALIKALEQLYSLGALNDKGELTKIGRQMAEFPTDPMIAKAILASDKYGCVEEVLSIVSM
LGEASALFFRPKEKRMFADQAREAFTRPGGDHLTLLEIWNQWVETDYSYQWTQENFLQYRSLSRARDVREQLERLCDRVE
IEVRSLEEGSSEGMEKIQKSIVSGFFANTAKMSRSGDSYQVIKTKQTVHIHPSSVLFSHKPRWLLYHELVLTSKEFMRNC
MPLKPEWLIEVAPHFYKTREIEELDSSTKKMPKKV

GO term prediction

Biological Process

GO:0006397 mRNA processing

Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding

Cellular Component

None predicted.