Protein

MIA_06116_1

Length
436 amino acids

Browser: contig10:299058-300369+

Protein function

EGGNOG:0PGS4PRS5ribose-phosphate pyrophosphokinase
SGD closest match:S000005422PRS5Ribose-phosphate pyrophosphokinase 5
CGD closest match:CAL0000197367PRS5Ribose phosphate diphosphokinase subunit

Protein alignments

%idAln lengthE-value
MCA_06130_166.595%4670.0MCA_06130_1
A0A0J9XJJ9_GEOCN66.055%4360.0Similar to Saccharomyces cerevisiae YKL181W PRS1 5-phospho-ribosyl-1(Alpha)-pyrophosphate synthetase OS=Geotrichum candidum GN=BN980_GECA25s00703g PE=4 SV=1
A0A1E3PLI9_9ASCO62.896%4420.0Phosphoribosyl pyrophosphokinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46675 PE=4 SV=1
A0A060T6L9_BLAAD60.959%4383.09e-180ARAD1B19866p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19866g PE=4 SV=1
Q6CG51_YARLI57.834%4343.96e-174YALI0B00836p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B00836g PE=4 SV=1
A0A167FYD6_9ASCO57.356%4695.88e-170Ribose phosphate diphosphokinase subunit PRS5 OS=Sugiyamaella lignohabitans GN=PRS5 PE=4 SV=1
UniRef50_A0A167FYD657.356%4691.62e-166Ribose phosphate diphosphokinase subunit PRS5 n=36 Tax=Fungi TaxID=4751 RepID=A0A167FYD6_9ASCO
Q5A2L2_CANAL65.182%2475.97e-109Ribose phosphate diphosphokinase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRS5 PE=4 SV=1
A0A1E4T9D4_9ASCO60.079%2534.29e-105Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58695 PE=4 SV=1
KPR5_YEAST50.159%3152.36e-92Ribose-phosphate pyrophosphokinase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRS5 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3110
Predicted cleavage: 12

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 436

Detailed signature matches

  1. Family IPR005946
    Ribose-phosphate diphosphokinase
    1. PF14572 (Pribosyl_s...)
    2. TIGR01251
  2. Domain IPR029057
    Phosphoribosyltransferase-like
    1. SSF53271 (PRTase-like)
  3. Domain IPR029099
    Ribose-phosphate pyrophosphokinase, N-terminal domain
    1. PF13793 (Pribosyltr...)
  4. Domain IPR000836
    Phosphoribosyltransferase domain
    1. cd06223 (PRTases_typeI)
  5. SITE IPR000842
    Phosphoribosyl pyrophosphate synthetase, conserved site
    1. PS00114 (PRPP_SYNTHASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SM01400 (Pribosyltr...)
  8. mobidb-lite (disord...)

Residue annotation

  1. active site cd06223

Protein sequence

>MIA_06116_1
MRNLVVLGGSSHPALVDRVCRNLNISPCEATLSKFANGETSITIKESVREKDVYVLQSASGAVNDHFIELLVMISACKTA
SARKVTAVLPLFPYSRQPDAPYAKRGAPLKKNGSAAPAGPTGSLNASAHNNNKPFTFESVPSSPRPASLPTSSSLTPLAL
SSSLNRLALAQRPALTRTDSWQPEAPSGHIETNSGYKEWVAQPGTLIASLLMAAGADHIITMDLHDPQFQGYFDVPVDNL
YGRPLLQHYISTCVPNYADDAVIVSPDAGGAKRATAVADALGMPFALIHKERRRAVAGSTGTVTPTSGSPGSASGARRLA
TTMLVGNVHGKIAVLVDDLVDTANTITRAAKLLKDQGATTVIAVITHGIFSGDAIERINASAIDKVVTTNTAPQDEHLAQ
LGDKLEVLDVGRVFAEAIRRIHNGESVSMLFDHVGI

GO term prediction

Biological Process

GO:0009116 nucleoside metabolic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0044249 cellular biosynthetic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity

Cellular Component

None predicted.