MCA_06130_1
Gene name: PRS5
Description: Ribose-phosphate pyrophosphokinase 5
Browser: contigD:3321913-3323311+
RNA-seq: read pairs 1578, FPKM 41.8, percentile rank 61.3% (100% = highest expression)
Protein function
| Annotation: | PRS5 | Ribose-phosphate pyrophosphokinase 5 | |
|---|---|---|---|
| KEGG: | K00948 | PRPS | ribose-phosphate pyrophosphokinase [EC:2.7.6.1] |
| EGGNOG: | 0PGS4 | PRS5 | ribose-phosphate pyrophosphokinase |
| SGD closest match: | S000005422 | PRS5 | Ribose-phosphate pyrophosphokinase 5 |
| CGD closest match: | CAL0000197367 | PRS5 | Ribose phosphate diphosphokinase subunit |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_06116_1 | 69.51% | 469 | 0.0 | MIA_06116_1 |
| A0A0J9XJJ9_GEOCN | 65.16% | 465 | 0.0 | Similar to Saccharomyces cerevisiae YKL181W PRS1 5-phospho-ribosyl-1(Alpha)-pyrophosphate synthetase OS=Geotrichum candidum GN=BN980_GECA25s00703g PE=4 SV=1 |
| A0A1E3PLI9_9ASCO | 60.43% | 465 | 0.0 | Phosphoribosyl pyrophosphokinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46675 PE=4 SV=1 |
| A0A167FYD6_9ASCO | 60.68% | 468 | 0.0 | Ribose phosphate diphosphokinase subunit PRS5 OS=Sugiyamaella lignohabitans GN=PRS5 PE=4 SV=1 |
| UniRef50_A0A167FYD6 | 60.68% | 468 | 5e-180 | Ribose phosphate diphosphokinase subunit PRS5 n=36 Tax=Fungi TaxID=4751 RepID=A0A167FYD6_9ASCO |
| A0A060T6L9_BLAAD | 57.67% | 463 | 1e-173 | ARAD1B19866p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19866g PE=4 SV=1 |
| Q5A2L2_CANAL | 53.44% | 479 | 2e-167 | Ribose phosphate diphosphokinase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRS5 PE=4 SV=1 |
| KPR5_YEAST | 47.87% | 516 | 9e-153 | Ribose-phosphate pyrophosphokinase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRS5 PE=1 SV=1 |
| Q6CG51_YARLI | 70.04% | 257 | 1e-121 | YALI0B00836p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B00836g PE=4 SV=1 |
| A0A1E4T9D4_9ASCO | 61.96% | 255 | 2e-104 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58695 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1400
Protein family membership
- Ribose-phosphate diphosphokinase (IPR005946)
Domains and repeats
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Domain
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Domain
Detailed signature matches
no IPR
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SM01400 (Pribosyltr...)
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mobidb-lite (disord...)
Residue annotation
-
active site cd06223
Protein sequence
>MCA_06130_1 MRDVVVLGGSSHPALVERICRYLNIDPCAATLSKFSNGETSITVKESVREKDVYVVQSGCGHVNDNFMELLIMISACKTA SAKKVTVVLPLFPYSRQPDAPYAKRGAPLRKNGKSSETISPTNGVSSSAAAASLANGNNKFTFESVPSSPRPHANGGPHP SSSLTPLALSASLGRLAVNGSNGTTASNRPTLGRSDSWQPTSKKSLETNTGYKEWVAQAGTLIASLLTCAGADHIITMDL HDPQFQGYFDIPVDNLYGKPLLQHYIVSSIPNFQEAVIVSPDAGGAKRATAIADALRMPFALIHKERRRQPQHTPTASNG SVVAAAEAHSPNANSSEIYGSGSSRRLATTMLVGNVRDRVAILVDDLIDTANTVTRAAKLLKDKGAVKVYAIITHGIFSG DAIERINASAIDKIITTNTTPQVEHMKQLLPGKLEVLDVGRVFAEAIRRIHNGESVSMLFDHVGI
GO term prediction
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0044249 cellular biosynthetic process
Molecular Function
GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity
Cellular Component
None predicted.