Protein

MIA_06115_1

Length
742 amino acids

Browser: contig10:296143-298533+

Protein function

EGGNOG:0PGRBHRK1HAL protein kinase
SGD closest match:S000005127NPR1Nitrogen permease reactivator protein
CGD closest match:CAL0000199299NPR1Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MCA_05789_177.719%3770.0MCA_05789_1
A0A0J9XE04_GEOCN78.324%3460.0Similar to Saccharomyces cerevisiae YBR274W CHK1 Serine/threonine kinase and DNA damage checkpoint effector OS=Geotrichum candidum GN=BN980_GECA10s00153g PE=4 SV=1
A0A060T731_BLAAD70.349%3444.47e-180ARAD1B19822p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19822g PE=4 SV=1
UniRef50_A0A060T73170.349%3441.10e-176ARAD1B19822p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A060T731_BLAAD
A0A1E3PL28_9ASCO61.480%3921.43e-174Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46672 PE=4 SV=1
Q6CG49_YARLI68.615%3251.92e-167YALI0B00880p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B00880g PE=4 SV=1
A0A1E4TB75_9ASCO65.361%3323.00e-163Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_53340 PE=4 SV=1
A0A167FYC5_9ASCO76.496%2344.89e-135Putative serine/threonine protein kinase HRK1 OS=Sugiyamaella lignohabitans GN=HRK1 PE=4 SV=1
A0A1D8PDY7_CANAL49.741%3861.78e-124Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NPR1 PE=4 SV=1
NPR1_YEAST51.567%3511.95e-117Nitrogen permease reactivator protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPR1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0363

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 742

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd13994 (STKc_HAL4_...)
  4. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd13994
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MIA_06115_1
MPEETLPDHHPVMSTDSQDSGSANAASSPSTATTTAESIVEPSSKPLASSSIPPNDAKAADASSPEHAQDLADRLSQVAL
GQSRLLPPDTNSYEHFSLPTTRVPTNETEGPGSTASSRHASVAEPAESSPATSNSQGTSAASQHDDNSPHDFPHPPTTAP
TQLSERPVLASRPSAAFLTAAADPYSSSSPSSSEPSSPKLGSRPGSPDPHASTAGPASSTIPKITHSPIHSRDASPAGRL
VPPPTNSSIKSSSTAAPLEKHKSSRFKLSSKFKKATHWDLHSSPTQQLQSNTHQSSSRASLDPHHPPHLHHHHDSDDNST
LASKHKSHGSMMELKRFFKSSSKKSDEKKRSGSFLSSNRSSSHITPAVPLDPAQAEAHHRAEIAAASSAFLSKSGSSASL
KDMPFAEDGFKKYGKIGRVLGSGAGGSVRLMKRNSDGTTFAIKEFRPRHPNESQKDYAKKVTAEFCIGSTLHHPNIIETL
DIIQDDGKYFEVMEYCPFDFFAIVMSGKMSRGEIGCTFKQILNGVTYLHSMGLAHRDLKLDNCVVTTEGIVKIIDFGSAS
VFKYPFENDVVRARGVVGSDPYLAPEVLTQPTYDPQPTDIWSLAVIYCCMTLRRFPWKVPRMSDNSFKLFATKPTKEEED
SYFQMGHEKEKDQPPAKDAPKIVIKGPWRLLRLLPHESRHIIGRMLEIDPTKRATLTEIWADEWIKKLHMCTLDKNGKFV
KAGTHEHTFVAEEEAHLEAYKK

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.