Protein

MCA_05789_1

Length
776 amino acids

Gene name: NPR1B

Description: Putative serine/threonine protein kinase Npr1; in S. cerevisiae stabilizes several plasma membrane amino acid transporters.

Browser: contigD:2341618-2344377+

RNA-seq: read pairs 8195, FPKM 130.3, percentile rank 83.0% (100% = highest expression)

Protein function

Annotation:NPR1BPutative serine/threonine protein kinase Npr1; in S. cerevisiae stabilizes several plasma membrane amino acid transporters.
EGGNOG:0PGRBHRK1HAL protein kinase
SGD closest match:S000005127NPR1Nitrogen permease reactivator protein
CGD closest match:CAL0000199299NPR1Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MIA_06115_177.98%3770.0MIA_06115_1
A0A0J9XE04_GEOCN69.23%3772e-176Similar to Saccharomyces cerevisiae YBR274W CHK1 Serine/threonine kinase and DNA damage checkpoint effector OS=Geotrichum candidum GN=BN980_GECA10s00153g PE=4 SV=1
UniRef50_A0A1E3QER958.82%4423e-156Uncharacterized protein n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3QER9_LIPST
A0A1E3PL28_9ASCO60.31%3933e-155Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46672 PE=4 SV=1
A0A060T731_BLAAD63.64%3748e-157ARAD1B19822p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19822g PE=4 SV=1
A0A1E4TB75_9ASCO58.09%3466e-141Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_53340 PE=4 SV=1
A0A167FYC5_9ASCO62.81%3203e-119Putative serine/threonine protein kinase HRK1 OS=Sugiyamaella lignohabitans GN=HRK1 PE=4 SV=1
Q6CG49_YARLI73.84%2376e-118YALI0B00880p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B00880g PE=4 SV=1
A0A1D8PDY7_CANAL48.61%3608e-114Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NPR1 PE=4 SV=1
NPR1_YEAST47.85%3492e-109Nitrogen permease reactivator protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPR1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1338

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 776

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. mobidb-lite (disord...)

Protein sequence

>MCA_05789_1
MPSLSNSSSSEKRSDSNPEVFSNSITNASTAATDPDLASHQEEPSSDGKNANINSLSEKLSEVALGQKRFLSTDTHHYEH
FSLPATRAHTNENIHKSNTTSTQGSKSPRNASATCSPIPTTPSKTPSAISETAVQNQNLIPKLIKENSNSSSGNIAAASP
VSTIKETSNASSSTRPSAVYLSAAQDPYNKPPEQSDSSTSPPKVNRSKFTVGSRDSSPAHSRESSPSRSAQQKQQPSSTP
SSGAITPKSPTTPTANVSSSLLLPPPKDTHAKQPTPEKPHKSSRFSFSKFKKAAHRDHSNEATPVSTNSSIFSKHHRTHE
SDNATPSTTNASKNPNKHGSSMMELKRFFKVSNKSKKDKEKEKERRAGASSTTAASTQRTERSTDIVGAGFHSSSSSTSL
KNMPFAEEGFKKYGKLGRLLGSGAGGSVRLMKRASDGTTFAIKEFRPRHPNESQKEYAKKVTAEFCIGSTLHHPNIIETL
DIIQDDGKFFEVMEYCPFDFFAIVMSGKMTKGEIGCTFKQIINGVTYLHKMGLAHRDLKLDNCVVTAEGIVKIIDFGSAS
VFRYPFENEIVKAKGVVGSDPYLAPEVFSQPNYDPRPTDVWSLAVIYCCMTLRRFPWKVPKMSDTSFKLFATKPTKEEEE
QYLEMSHSSHHHHHKKTEESSSEKKDASSTTSSQPKESAQKSAEKPTEKPAAPQQKIVIKGPWRLLRLLPHESRHIIGRM
LELDPKKRADLEEIWQDEWIKKIHMCTLDKDGKFVKAGTHEHTLVNEEEAHLESYK

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.