Protein
MIA_06108_1
Length
1,485 amino acids
Browser: contig10:250938-255446+
Protein function
EGGNOG: | 0PFX4 | CFT1 | RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4 CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation |
---|---|---|---|
SGD closest match: | S000002709 | CFT1 | Protein CFT1 |
CGD closest match: | CAL0000179267 | CFT1 | Protein CFT1 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_02702_1 | 53.182% | 707 | 0.0 | MCA_02702_1 |
A0A0J9X2I9_GEOCN | 45.429% | 700 | 0.0 | Similar to Saccharomyces cerevisiae YDR301W CFT1 RNA-binding subunit of the mRNA cleavage and polyadenylation factor OS=Geotrichum candidum GN=BN980_GECA01s02353g PE=4 SV=1 |
UniRef50_A0A0J9X2I9 | 45.429% | 700 | 0.0 | Similar to Saccharomyces cerevisiae YDR301W CFT1 RNA-binding subunit of the mRNA cleavage and polyadenylation factor n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2I9_GEOCN |
A0A060TES3_BLAAD | 40.181% | 662 | 2.44e-156 | ARAD1D10230p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D10230g PE=4 SV=1 |
A0A167CXI4_9ASCO | 46.693% | 499 | 2.75e-160 | Cft1p OS=Sugiyamaella lignohabitans GN=CFT1 PE=4 SV=1 |
A0A1E3PEB4_9ASCO | 39.028% | 679 | 1.47e-141 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84410 PE=4 SV=1 |
A0A1E4TBU3_9ASCO | 26.465% | 1587 | 1.64e-132 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3763 PE=4 SV=1 |
CFT1_CANAL | 35.906% | 596 | 1.16e-110 | Protein CFT1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFT1 PE=3 SV=2 |
CFT1_YARLI | 39.529% | 425 | 3.07e-97 | Protein CFT1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CFT1 PE=3 SV=1 |
CFT1_YEAST | 34.798% | 569 | 2.59e-96 | Protein CFT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CFT1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.5085
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
200
400
600
800
1000
1200
1485
Detailed signature matches
Protein sequence
>MIA_06108_1 MQIIKQLTAPSTVTHALYCAFTGAPDLDLLVVRGSNLLQLYHTVRTQTQVVETPENDEKTSIEKNEDAAAMEDRRLEGED TFIGSETALEVAREEFSAKLVLVAEWNLQGQITGLAAINTYADIAATKKSGGIEKRSLIVSFKYAKMSIVAWDPFQHNII TQSLHYYERDFFELDFVDPTFQPKLAVDPLSAAATLLYQHDMLVFLPFVRDELLDDPIATAPQLASSATSDFAQLLQQAQ KETGSFQSQSGLQQQQQPPLPPISQPSFMIRATEMHESITNIIDITYLYEYREPTIAILYEPIRTWAGRLQLEKDTVSYL VLSVDLQAHTFTSIFSVNNLPYNVRTIIPLRDPIGGSLLVGTNEFIHVDSQGRVNGVFVNPLHSISSELELKDQSSLSLF LEGCQAHQLDGGADDQVVVVLESGELLTLRFHIESRKVYELTVSKLPKDIRIPNPTLIASLKTRYLFVGSATADSRLIQW KRQGEITADDDTKTAVLTSQPAPKETATESTHDDIDDIYGNLADQPVKQTSSAINSGFSDLPIVIRVTDKLSNYGPINDM VACRAPEEYDAGDETSLDIVAATGTGADKSLTVFTRKLRPQVASTLKLKNSFKRIWTLRPASLSSDSYTADEEGLFDTYL VGSNDKSTFIFQIGQEFVDITSKVSKLRSCGPTLACSTVFNGRIVVFVCEAGIVLYDSELTYITRKRLKSPPANIVFADE YIVVNFDENTQAIYHVKKKKKVISVEVSKIKEESLPAADTTPATPAELDGTPNPETEELESTPIATPATTSVITWDITER APSSKLPPPSGLFAGTSSVFSSALIGDSKRVKRKLDEKEVEHPQKEPSVPILYSVGKEGTLYAVYLTDSSVRFDMSALMH LPNVLRLKDRTFVDDSIAQAPQATSSQIPTVKIHQISHFTIKNGIEEGEYLALLTSDSFHLIIYQFLQTPNGEIVLIKSR DSLGIPTLSNAKTNFLPKIIPFTNISGYAGIFVVGPVPLIIFKPPQSPIMYHKLAVPDNSPAIGFTQFNTAAVYSGLAYI DNSFVLRIATLPNDVDFGCAWPARRINLSAPVLSIAYHETSNILAVALLTSHEFEALDPEGNPIPDLNLKMPRPTAYQSS LKLLSPESWKVIDSVEYQTNESIMTLKSVMLEVSEKTHQKKEFIVAGTSVIRGEDLAAQGGFYIYEIIEVVPEPGRPETS HKLKQISFEVSKGAVTSICEVSGNLLIAQAQKVVVRNIQEDNSVVPVAFMDMNTYVSSCKSIKYMVLLSDAIRSVWLVGF GKEPYRMTLFGKDYQNVEVTSCDFIVFDKTLHILVADTQQRLHVLQYDPEDPSPFSGQKLLRRSEMFLGRDIDTMLLLPY TSSQTPLPGFIPLCGARDGSLLTIVPVTEATYRALYVIQQQISDREEHTLGLNPRMHHAMGVSAGGPVSGQGQAQSRQLL DYNLVRRFIDLPVERRSQYVRRLGKTGYDDVWKALRVVDEVLEYL
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0005515 protein binding
Cellular Component
GO:0005634 nucleus