Protein
MCA_02702_1
Length
1,404 amino acids
Gene name: CFT1
Description: Protein CFT1
Browser: contigB:2095153-2099368+
RNA-seq: read pairs 2030, FPKM 17.9, percentile rank 38.2% (100% = highest expression)
Protein function
| Annotation: | CFT1 | Protein CFT1 | |
|---|---|---|---|
| KEGG: | K14401 | CPSF1 | cleavage and polyadenylation specificity factor subunit 1 |
| EGGNOG: | 0PFX4 | CFT1 | RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4 CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation |
| SGD closest match: | S000002709 | CFT1 | Protein CFT1 |
| CGD closest match: | CAL0000179267 | CFT1 | Protein CFT1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X2I9_GEOCN | 42.02% | 1416 | 0.0 | Similar to Saccharomyces cerevisiae YDR301W CFT1 RNA-binding subunit of the mRNA cleavage and polyadenylation factor OS=Geotrichum candidum GN=BN980_GECA01s02353g PE=4 SV=1 |
| UniRef50_A0A0J9X2I9 | 42.02% | 1416 | 0.0 | Similar to Saccharomyces cerevisiae YDR301W CFT1 RNA-binding subunit of the mRNA cleavage and polyadenylation factor n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2I9_GEOCN |
| A0A060TES3_BLAAD | 35.00% | 1417 | 0.0 | ARAD1D10230p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D10230g PE=4 SV=1 |
| MIA_06108_1 | 53.18% | 707 | 0.0 | MIA_06108_1 |
| A0A1E3PEB4_9ASCO | 35.78% | 1076 | 2e-172 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84410 PE=4 SV=1 |
| CFT1_YARLI | 29.53% | 1412 | 8e-166 | Protein CFT1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CFT1 PE=3 SV=1 |
| CFT1_CANAL | 28.45% | 1399 | 5e-157 | Protein CFT1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFT1 PE=3 SV=2 |
| A0A167CXI4_9ASCO | 47.86% | 514 | 1e-149 | Cft1p OS=Sugiyamaella lignohabitans GN=CFT1 PE=4 SV=1 |
| CFT1_YEAST | 26.85% | 1389 | 1e-124 | Protein CFT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CFT1 PE=1 SV=1 |
| A0A1E4TBU3_9ASCO | 27.73% | 1475 | 4e-123 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3763 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0989
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
200
400
600
800
1000
1200
1404
Detailed signature matches
-
-
PF03178 (CPSF_A)
-
no IPR
Unintegrated signatures
-
PF10433 (MMS1_N)
Protein sequence
>MCA_02702_1 MNAYKSLVPPSVVSHSLPCKFTGSDDLIIVRGSSLLQLYKTVKTQTHVVENKDDEDNENEDLGATGEKKLLEAQDTFIGT EITLQAMREETTPKLVLVKEWPLYGQVTGIKKVNLLAHPKRDCLVISFRYGKISIVSWDAETQSISTQSLHYYEKNISDS HFFDSLFEAKLSVDPNSASATLLFQQDTLVFLPFAQDELLDESTAAPLNGVSNGLQQPNTKPLIPIFRPSFILKALDIDE SISNVIDFTYLFEYRIPTIAILFEPNRTWACRLQLNKDSVCYMVLSLDLSQQTFTSILSVQNLPYSIQKLVPLKDPLGGC LLVGTNELIHIDSQGRVNGASVNPFHKISSDLELKDLSSLNIFLENAVISGLDGADEEAILVTEEGVLYKLNFVIESRKV QEILISKLPTDINVPRPTTLSLLPSRCIFIGSNTSDSKLIQWKRKGEITADDDNKTAVVFEKPTEDENENMEDDHDAIDD IYGDMDPDDSKATLKNQKKMRGAESLAPIVVRLCDTLNNYGPINDIAVCRATDSQTGNPIENQFDIVAASGVGPGRSLTV FNTKLRPAIVSRLKLRSQFSKVWAINPSGISESTQNEESDDSNVFDAFLIGSTSESTSIFRIGEDFEDITSNIPGFKSDI PTISAKVAFNSRIVILVCSKLIALYDSDMSLITETPIEKEPSLVTFADSYVVLHYENSEPSIYNIKELFENKWEIKQLQY SLSGTTYMSAATSTCFYSILSSDAKRIKRKLDEQEVKANAPSPIPVGYSTTSDSVKLFPLNSLSSSVDLTALLNLPNCLK YDDEKRAFIDCGPKLVQTQQQKPIDNTDISISQLQHFKLGNSGESEEYLAILTKTNELYVYHIIQNSYGTFIIKDRDGYN IHTLTKTKEGATSYPPKLIQYESIGEFSGLFVLGEKPMMLLKEKQSSLQYHIFDSINPVVGFTTFNTPSVFGGMAYVDSK FVLNIATLPQDFFLGLPWPAKKVDLGGPVLSLCYHDTGHVLAVSVTTESDYNALDPDDNPIPDLDLEMPRPKAYSSVLKI ISPKSWTAIDEAPCTDPNESIMTMKSVFLEVSEKTKQMKEFLVIGTSIIRGEDLAASGGFYIYDVIEVVPEPGKPETNHK LKLVTSEVSKGAVTSVCEVSGHLLVAQAQKVVVRNIQEDNSVVPVAFLDMNMYVNCTKSIKYMVLLSDAIRSVWLVGFGK EPFRMTLFGKDYRDIQVTSCEFLVFDKHLYIVAADTHQRLHVLQYDPEDPQPFSGQKLIRRSEFFVGSEMNTMIMLPLAK PSKSSPTPPSVSTLVPLCGASDGSISVVLPVSESRFRALYVIQQQIADKEEHYCGLNPRMHRALGIEPANSNSQGKILID FSLVKKFYDLPANRRALYSRRLGVSGQQQAADSIRHINEALEYL
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0005515 protein binding
Cellular Component
GO:0005634 nucleus