Protein

MIA_06092_1

Length
443 amino acids

Browser: contig10:204510-205842+

Protein function

EGGNOG:0PISDINT6Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity)

Protein alignments

%idAln lengthE-value
MCA_05147_171.267%4420.0MCA_05147_1
A0A0J9X3J2_GEOCN65.596%4360.0Eukaryotic translation initiation factor 3 subunit E OS=Geotrichum candidum GN=INT6 PE=3 SV=1
UniRef50_A0A0J9X3J265.596%4360.0Eukaryotic translation initiation factor 3 subunit E n=18 Tax=Fungi TaxID=4751 RepID=A0A0J9X3J2_GEOCN
A0A060T492_BLAAD60.538%4460.0Eukaryotic translation initiation factor 3 subunit E OS=Blastobotrys adeninivorans GN=INT6 PE=3 SV=1
A0A167FIQ2_9ASCO61.573%4450.0Eukaryotic translation initiation factor 3 subunit E OS=Sugiyamaella lignohabitans GN=INT6 PE=3 SV=1
A0A1E3PJ91_9ASCO54.054%4442.41e-171Eukaryotic translation initiation factor 3 subunit E OS=Nadsonia fulvescens var. elongata DSM 6958 GN=INT6 PE=3 SV=1
EIF3E_YARLI55.083%4233.26e-162Eukaryotic translation initiation factor 3 subunit E OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=INT6 PE=3 SV=1
A0A1E4TI80_9ASCO42.273%4407.03e-109Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_15354 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0924

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 400 443

Detailed signature matches

  1. Family IPR016650
    Eukaryotic translation initiation factor 3 subunit E
    1. PIRSF016255 (Transl...)
    2. MF_03004 (eIF3e)
  2. Domain IPR019010
    Eukaryotic translation initiation factor 3 subunit E, N-terminal
    1. SM01186 (eIF3_N_2)
    2. PF09440 (eIF3_N)
  3. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
  4. Domain IPR000717
    Proteasome component (PCI) domain
    1. SM00088 (PINT_4)
    2. PF01399 (PCI)
  5. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
    2. SSF46785 ("Winged h...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SM00753 (PINT)

Protein sequence

>MIA_06092_1
MSTAKTSPEALELARKYDLTQKILPFLDPHLVYPIAEFLGKKGIYSSKTLDQLQYDLFQNSCMFDFISDLWKKLHPNETA
PSLDDRKADLEARIATYERDQNTVSEVFENPEVQANLKADKVQNLRMLEKYNITVDLINSFYYFGKANFSRGDYAAASRK
LQQFLLLSTDAKLIASAHWGKFASDLLAGETEAALEDQQSLRDIVDQRSFADPLTQLHNRTWIIHWSLFLLQNPNFNKEG
LVDLFFSASYISTIQASCPWIIRYLAAAVISLNTKGRNNSSNQRRLKDLVRVVGQELYEYQDPITDFVRALYIDYDFAEA
QSKLLEAESILANDFFLHNLTDSFLDSARHLVSELYCRIHQRIDVKQLSARLNLSPEQGEKWIANLIKDTKMDAKINESD
GTVIMNHPVTSVYQQVIEKTKGLTFRSNQILAQALNKNESVVA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003743 translation initiation factor activity
GO:0005515 protein binding

Cellular Component

GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex