Protein

MIA_06084_1

Length
622 amino acids

Browser: contig10:175502-177371+

Protein function

EGGNOG:0PFE6FG02869.1MFS multidrug transporter
SGD closest match:S000006360TPO3Polyamine transporter 3
CGD closest match:CAL0000181961orf19.341Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_00877_171.14%5440.0MCA_00877_1
A0A167D3I8_9ASCO60.27%5210.0Tpo3p OS=Sugiyamaella lignohabitans GN=TPO3 PE=4 SV=1
A0A060SYR6_BLAAD59.54%5240.0ARAD1A19096p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A19096g PE=4 SV=1
UniRef50_A0A060SYR659.54%5240.0ARAD1A19096p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060SYR6_BLAAD
Q6C539_YARLI55.64%5320.0YALI0E21241p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21241g PE=4 SV=1
A0A1D8PJQ4_CANAL45.08%5396e-168Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.341 PE=4 SV=1
A0A1E3PPH0_9ASCO33.27%5206e-82MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81829 PE=4 SV=1
A0A0J9X353_GEOCN32.42%5129e-81Similar to Saccharomyces cerevisiae YLL028W TPO1 Polyamine transporter that recognizes spermine, putrescine,and spermidine OS=Geotrichum candidum GN=BN980_GECA01s01011g PE=4 SV=1
A0A1E4TAB0_9ASCO32.81%5064e-77Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_127309 PE=4 SV=1
TPO3_YEAST31.93%5234e-67Polyamine transporter 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4478
Predicted cleavage: 18

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 622

Detailed signature matches

  1. Family IPR011701
    Major facilitator superfamily
    1. PF07690 (MFS_1)
  2. Domain IPR020846
    Major facilitator superfamily domain
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
  3. SITE IPR005829
    Sugar transporter, conserved site
    1. PS00216 (SUGAR_TRAN...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.12...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Residue annotation

  1. putative substrate...

Protein sequence

>MIA_06084_1
MTSPANPSSASPAIKRTESHSSSSSDPISEPTPFHLEHLTPVPDASPAGSLRGKSLSEKPITETSSDNDDNDDYAKFKNG
TLSPALSRASYRSTRSGYSRRDIYGDASDEQVALEREKTIEQVMSRVTTHRHIDDVVPEETENGLPDDGEQYVEIDPELV
TWEGDDDPENPRNWPRKKKWVTTIIVAVYTFISPLASSIIAPAVQNMSENLHVTKQIEQSLTVSIFVLAWAICPLFVAPL
SEVFGRRVVLNIAIVLMTIFNMACALSRNIAQLLVFRFLAGCAGAPPLSIGAGTMADLFNDKERNNALALYAVGPTVGPV
VAPIIAGFIAENTTWRWVIWVLTIFNGVIAFLGCIFYRETYAPVLLKWKAARLRKETGNEHLHTVFELTKEPFLHQLYTA
VTRPLRLLLMHPIVQGLGLYMAFVYGFMYLMLVTFPSLWTQHYGFSLGIAGLMYLSLGIGFCLGLVFWAWSIQWAYLKLT
ERNGGVPKPEYRIPMAPMSGVCLGIGLLWYGWSAQAHIMWLMPCIGAGIFAFGIVAVFQCIQNYLIDMNPRFSASSMASA
QVFRSYLGFGFPLFGKAMYDKLGYGWANTISGLLCFVLGIPFPIFVYLYGERLRNWANKKFS

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016021 integral component of membrane