Protein

MIA_06067_1

Length
375 amino acids

Browser: contig10:117283-118411-

Protein function

EGGNOG:0PGTGFG03210.1NADH flavin oxidoreductase NADH oxidase family protein
SGD closest match:S000006092OYE3NADPH dehydrogenase 3
CGD closest match:CAL0000176070OYE22Oye22p

Protein alignments

%idAln lengthE-value
MCA_00987_155.851%3761.39e-149MCA_00987_1
A0A0J9XEE0_GEOCN48.229%3673.66e-120Similar to Saccharomyces cerevisiae YHR179W OYE2 Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) OS=Geotrichum candidum GN=BN980_GECA12s03805g PE=4 SV=1
A0A167DHV9_9ASCO48.066%3629.35e-117Oye2p OS=Sugiyamaella lignohabitans GN=OYE2 PE=4 SV=1
A0A060TFD9_BLAAD46.649%3733.12e-114ARAD1D22418p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22418g PE=4 SV=1
UniRef50_A0A1E3NVC346.597%3822.63e-105Uncharacterized protein n=6 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3NVC3_WICAO
Q6C0L5_YARLI46.237%3722.04e-105YALI0F23661p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23661g PE=4 SV=1
OYE3_YEAST44.648%3831.00e-103NADPH dehydrogenase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OYE3 PE=1 SV=2
A0A1E3PIH8_9ASCO42.228%3863.90e-95NADH:flavin oxidoreductase/NADH oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46861 PE=4 SV=1
Q5A894_CANAL38.974%3902.44e-84Oye22p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=OYE22 PE=4 SV=1
A0A1E4TKU7_9ASCO38.320%3811.40e-73Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22517 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8187
Predicted cleavage: 34

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 375

Detailed signature matches

  1. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  2. Domain IPR001155
    NADH:flavin oxidoreductase/NADH oxidase, N-terminal
    1. PF00724 (Oxidored_FMN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF51395 (FMN-linke...)
  2. cd02933 (OYE_like_FMN)

Residue annotation

  1. active site cd02933
  2. FMN binding site c...
  3. substrate binding ...
  4. catalytic residue ...

Protein sequence

>MIA_06067_1
MSALKNNLFKPITVGRVQLTQRIAMAPLTRVRADPETAVPTEVMETYYKQRSQAPGTLIVSEATVISERARAYRGVPGVW
SPEQVSGWKKITSTVHQQDSFIFQQLWAVGRAANPKYLSALGNDFVSSSNVPDLTNPYHQEGVIPRALTADEIKEYVKDF
AQAAQNSVEAGFDGIEIHAANGYLLHQFLDDSVNHRTDNYGGSVENRARFTLEVVDAICKAIGADRVAIRLSPYETYGDM
KYGPATLEQYAYLLKELEERGLQPGGRLAYIHTVENTFDATNSVGEPILKWPLEFVRNVWTGVWIRTQHFSRDLALKFAD
VDDKLVIGFGKMFISNPDLVRRIKEDLPLATPDFTKLYTGGASGYTDYPEYGEKN

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.