Protein

MCA_00987_1

Length
395 amino acids

Gene name: OYE2A

Description: NADPH dehydrogenase 2; NADH flavin oxidoreductase NADH oxidase family protein

Browser: contigA:3142340-3143528-

RNA-seq: read pairs 2018, FPKM 63.0, percentile rank 70.3% (100% = highest expression)

Protein function

Annotation:OYE2ANADPH dehydrogenase 2; NADH flavin oxidoreductase NADH oxidase family protein
KEGG:K00354E1.6.99.1 NADPH2 dehydrogenase [EC:1.6.99.1]
EGGNOG:0PGTGFG03210.1NADH flavin oxidoreductase NADH oxidase family protein
SGD closest match:S000001222OYE2NADPH dehydrogenase 2
CGD closest match:CAL0000199513EBP1Ebp1p

Protein alignments

%idAln lengthE-value
MIA_00225_158.99%3786e-166MIA_00225_1
A0A0J9XEE0_GEOCN48.01%3771e-115Similar to Saccharomyces cerevisiae YHR179W OYE2 Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) OS=Geotrichum candidum GN=BN980_GECA12s03805g PE=4 SV=1
A0A167DHV9_9ASCO46.13%3751e-108Oye2p OS=Sugiyamaella lignohabitans GN=OYE2 PE=4 SV=1
UniRef50_A0A1E3NVC345.34%3862e-104Uncharacterized protein n=6 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3NVC3_WICAO
Q6C0L5_YARLI46.19%3818e-106YALI0F23661p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23661g PE=4 SV=1
A0A060TGC2_BLAAD44.30%3774e-105ARAD1D22440p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22440g PE=4 SV=1
OYE2_YEAST41.50%4008e-97NADPH dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OYE2 PE=1 SV=3
A0A1E3PIH8_9ASCO40.66%3962e-95NADH:flavin oxidoreductase/NADH oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46861 PE=4 SV=1
A0A1D8PPK1_CANAL41.10%3829e-80Ebp1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EBP1 PE=4 SV=1
A0A1E4TKU7_9ASCO40.58%3777e-75Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22517 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0232
Predicted cleavage: 56

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 395

Detailed signature matches

  1. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  2. Domain IPR001155
    NADH:flavin oxidoreductase/NADH oxidase, N-terminal
    1. PF00724 (Oxidored_FMN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF51395 (FMN-linke...)
  2. cd02933 (OYE_like_FMN)

Residue annotation

  1. active site cd02933
  2. FMN binding site c...
  3. substrate binding ...
  4. catalytic residue ...

Protein sequence

>MCA_00987_1
MSKAENIANTALFTPLKVGNFEIKQRMAMSAMTRCRADAQSVPTPRMVTYYSQRSSAPGTLVITEGTMITERGGGQKYVP
GIWSKEQIEGWKKVTDAVHKNKSFIFLQLWAVGRQACYQYLTKELGHDLVSASALRDETDAQAGISRLPNSEEEGTPRPL
TVKEIKEYVADFAQAAKNAIEAGFDGVEIHNANGYLLEQFNKLSTNKRTDEYGGSIPNLARFSLEVVDAVIEAVGPERTA
IRLSPYETYGGMTNGPETLPTYAYLLYQLELRGLANKRLAYVHTIENLVKKTAVDGSPVVLHPMDFVRFIWSGVWMRTQH
YSREDAIKMTNNDDKLIIGFAKLFLANPDLVRRFKENLPVTHWNYKYFYTQTEEGYIDYPFYDEEKNKNDDDSKK

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.