Protein

MIA_06063_1

Length
384 amino acids

Browser: contig10:111938-113093-

Protein function

EGGNOG:0PI5TCKA1casein kinase ii
SGD closest match:S000001297CKA1Casein kinase II subunit alpha
CGD closest match:CAL0000178518CKA1Casein kinase 2 catalytic subunit

Protein alignments

%idAln lengthE-value
A0A0J9X6R2_GEOCN67.539%3828.21e-169Similar to Saccharomyces cerevisiae YOR061W CKA2 Alpha' catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation OS=Geotrichum candidum GN=BN980_GECA03s02683g PE=3 SV=1
MCA_04560_182.996%2473.54e-155MCA_04560_1
UniRef50_R9P6T460.422%3795.27e-139Serine/threonine protein kinase n=1 Tax=Pseudozyma hubeiensis (strain SY62) TaxID=1305764 RepID=R9P6T4_PSEHS
A0A161HHJ2_9ASCO76.543%2433.15e-141Casein kinase 2 catalytic subunit CKA2 OS=Sugiyamaella lignohabitans GN=CKA2 PE=3 SV=1
A0A060T2F3_BLAAD73.750%2401.54e-133ARAD1C28204p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28204g PE=3 SV=1
A0A1E4TLZ5_9ASCO72.385%2391.50e-133Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_92635 PE=3 SV=1
A0A1E3PNU0_9ASCO72.016%2436.85e-132Casein kinase II OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81701 PE=3 SV=1
Q6C8U8_YARLI70.782%2434.51e-128YALI0D16863p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D16863g PE=3 SV=1
CSK21_YEAST66.250%2408.58e-117Casein kinase II subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CKA1 PE=1 SV=1
A0A1D8PUA2_CANAL63.374%2433.85e-116Casein kinase 2 catalytic subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CKA1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3963

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 384

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd14132 (STKc_CK2_a...)
  4. mobidb-lite (disord...)

Residue annotation

  1. tetramer interface...
  2. CK2 beta interface...
  3. allosteric inhibit...
  4. active site cd14132
  5. ATP binding site c...
  6. polypeptide substr...
  7. activation loop (A...

Protein sequence

>MIA_06063_1
MVKSVARVYANYNKDMPSSYWDYEHVKINWGSLNYYEILRKVGRGKYSEAFEGINIGSLNMGSNSKSNNSSSNNKGTPDK
ASGSAAAGSSSSASSSPSSSSSSSATDIPEFETCVIKVLKPVRKKKIKREIKILQNLAGGTNIVTLLDVVRDPTSKTPSL
IFEYINNVDFRILYPKFTNYDIQYYMFELLKALDYCHSKGIMHRDVKPHNIMIDHPNRKLRLIDWGLAEFYHPEIEYNVR
VASRCYKGPELLVDFQMYDYSLDLWSLGAVLAAMIFKIDPFFHGSSNTNQLIKIAQVLGTDELFRYLAKYDTPLPPEYDN
ILGVYPRQPWSSFINKTNEQFATPRAIDFIDKLLRYDHQERLTAQEAMAHPYFDDVRPILAPSV

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.