MIA_06062_1

Protein

Length

1,972 amino acids

Protein function

EGGNOG:	0PGS1	CYR1	Adenylate cyclase
SGD closest match:	S000003542	CYR1	Adenylate cyclase
CGD closest match:	CAL0000178292	CYR1	Adenylate cyclase

Protein alignments

	%id	Aln length
MCA_04561_1	67.699%	1582	MCA_04561_1
A0A0J9X5K6_GEOCN	58.227%	1489	Similar to Saccharomyces cerevisiae YJL005W CYR1 Adenylate cyclase OS=Geotrichum candidum GN=BN980_GECA03s02672g PE=4 SV=1
UniRef50_A0A0J9X5K6	58.227%	1489	Similar to Saccharomyces cerevisiae YJL005W CYR1 Adenylate cyclase n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5K6_GEOCN
A0A060T8C0_BLAAD	53.436%	1557	ARAD1C28182p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28182g PE=4 SV=1
A0A167FNF3_9ASCO	53.092%	1520	Adenylate cyclase OS=Sugiyamaella lignohabitans GN=CYR1 PE=4 SV=1
Q6CE40_YARLI	52.197%	1502	YALI0B18759p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B18759g PE=4 SV=1
A0A1E3PLW2_9ASCO	54.274%	936	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82247 PE=4 SV=1
A0A1D8PR83_CANAL	45.714%	910	Adenylate cyclase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CYR1 PE=4 SV=1
A0A1E4THH8_9ASCO	45.222%	900	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2922 PE=4 SV=1
CYAA_YEAST	42.809%	890	Adenylate cyclase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CYR1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0151

Protein family membership

None predicted.

Domains and repeats

Domain
429 - 519
Ras-associating (RA) domain (IPR000159)
1,194 - 1,494
PPM-type phosphatase domain (IPR001932)
Domain
500 - 813
Leucine-rich repeat domain, L domain-like (IPR032675)
796 - 918
Leucine-rich repeat domain, L domain-like (IPR032675)
986 - 1,221
Leucine-rich repeat domain, L domain-like (IPR032675)
1,456 - 1,785
Nucleotide cyclase (IPR029787)
Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054)
Repeat
569 - 590
Leucine-rich repeat (IPR001611)
616 - 684
Leucine-rich repeat (IPR001611)
686 - 707
Leucine-rich repeat (IPR001611)
709 - 777
Leucine-rich repeat (IPR001611)
821 - 842
Leucine-rich repeat (IPR001611)
844 - 911
Leucine-rich repeat (IPR001611)
1,016 - 1,085
Leucine-rich repeat (IPR001611)
1,088 - 1,109
Leucine-rich repeat (IPR001611)
Repeat
638 - 660
Leucine-rich repeat, typical subtype (IPR003591)
661 - 683
Leucine-rich repeat, typical subtype (IPR003591)
684 - 707
Leucine-rich repeat, typical subtype (IPR003591)
731 - 752
Leucine-rich repeat, typical subtype (IPR003591)
753 - 776
Leucine-rich repeat, typical subtype (IPR003591)
819 - 841
Leucine-rich repeat, typical subtype (IPR003591)
842 - 864
Leucine-rich repeat, typical subtype (IPR003591)
865 - 888
Leucine-rich repeat, typical subtype (IPR003591)
1,038 - 1,061
Leucine-rich repeat, typical subtype (IPR003591)
1,062 - 1,085
Leucine-rich repeat, typical subtype (IPR003591)
1,086 - 1,109
Leucine-rich repeat, typical subtype (IPR003591)

1 200 400 600 800 1000 1200 1400 1600 1800 1972

Detailed signature matches

IPR000159

Ras-associating (RA) domain
1. PS50200 (RA)
  
  429 - 519
  
  PROSITE profiles
  PS50200 (RA)
IPR032675

Leucine-rich repeat domain, L domain-like
1. SSF52058 (L domain-...)
  
  796 - 910
  
  SUPERFAMILY
  SSF52058 (L domain-like)
  
  1,013 - 1,189
  
  SUPERFAMILY
  SSF52058 (L domain-like)
  
  545 - 813
  
  SUPERFAMILY
  SSF52058 (L domain-like)
2. G3DSA:3.80.10.10
  
  644 - 801
  
  GENE3D
  G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
  
  802 - 918
  
  GENE3D
  G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
  
  986 - 1,069
  
  GENE3D
  G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
  
  1,070 - 1,221
  
  GENE3D
  G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
  
  500 - 643
  
  GENE3D
  G3DSA:3.80.10.10 (G3DSA:3.80.10.10)
IPR001932

PPM-type phosphatase domain
1. SM00332 (PP2C_4)
  
  1,194 - 1,488
  
  SMART
  SM00332 (PP2C_4)
2. G3DSA:3.60.40.10
  
  1,222 - 1,494
  
  GENE3D
  G3DSA:3.60.40.10 (G3DSA:3.60.40.10)
3. PF00481 (PP2C)
  
  1,239 - 1,483
  
  Pfam
  PF00481 (PP2C)
4. PS51746 (PPM_2)
  
  1,214 - 1,490
  
  PROSITE profiles
  PS51746 (PPM_2)
5. SSF81606 (PP2C-like)
  
  1,195 - 1,490
  
  SUPERFAMILY
  SSF81606 (PP2C-like)
IPR029787

Nucleotide cyclase
1. SSF55073 (Nucleotid...)
  
  1,757 - 1,778
  
  SUPERFAMILY
  SSF55073 (Nucleotide cyclase)
  
  1,551 - 1,721
  
  SUPERFAMILY
  SSF55073 (Nucleotide cyclase)
IPR001054

Adenylyl cyclase class-3/4/guanylyl cyclase
1. PS50125 (GUANYLATE_...)
  
  1,560 - 1,697
  
  PROSITE profiles
  PS50125 (GUANYLATE_CYCLASE_2)
2. G3DSA:3.30.70...
  
  1,544 - 1,785
  
  GENE3D
  G3DSA:3.30.70.1230 (G3DSA:3.30.70.1230)
3. PF00211 (Guanylate_cyc)
  
  1,555 - 1,730
  
  Pfam
  PF00211 (Guanylate_cyc)
4. SM00044 (cyc_6)
  
  1,456 - 1,734
  
  SMART
  SM00044 (cyc_6)
IPR001611

Leucine-rich repeat
1. PF13855 (LRR_8)
  
  1,017 - 1,075
  
  Pfam
  PF13855 (LRR_8)
  
  709 - 766
  
  Pfam
  PF13855 (LRR_8)
  
  844 - 901
  
  Pfam
  PF13855 (LRR_8)
  
  619 - 674
  
  Pfam
  PF13855 (LRR_8)
2. PS51450 (LRR)
  
  1,016 - 1,039
  
  PROSITE profiles
  PS51450 (LRR)
  
  616 - 637
  
  PROSITE profiles
  PS51450 (LRR)
  
  1,040 - 1,061
  
  PROSITE profiles
  PS51450 (LRR)
  
  1,088 - 1,109
  
  PROSITE profiles
  PS51450 (LRR)
  
  663 - 684
  
  PROSITE profiles
  PS51450 (LRR)
  
  867 - 888
  
  PROSITE profiles
  PS51450 (LRR)
  
  890 - 911
  
  PROSITE profiles
  PS51450 (LRR)
  
  640 - 661
  
  PROSITE profiles
  PS51450 (LRR)
  
  821 - 842
  
  PROSITE profiles
  PS51450 (LRR)
  
  755 - 777
  
  PROSITE profiles
  PS51450 (LRR)
  
  733 - 754
  
  PROSITE profiles
  PS51450 (LRR)
  
  1,064 - 1,085
  
  PROSITE profiles
  PS51450 (LRR)
  
  569 - 590
  
  PROSITE profiles
  PS51450 (LRR)
  
  844 - 865
  
  PROSITE profiles
  PS51450 (LRR)
  
  686 - 707
  
  PROSITE profiles
  PS51450 (LRR)
IPR003591

Leucine-rich repeat, typical subtype
1. SM00369 (LRR_typ_2)
  
  731 - 752
  
  SMART
  SM00369 (LRR_typ_2)
  
  684 - 707
  
  SMART
  SM00369 (LRR_typ_2)
  
  819 - 841
  
  SMART
  SM00369 (LRR_typ_2)
  
  842 - 864
  
  SMART
  SM00369 (LRR_typ_2)
  
  1,086 - 1,109
  
  SMART
  SM00369 (LRR_typ_2)
  
  661 - 683
  
  SMART
  SM00369 (LRR_typ_2)
  
  753 - 776
  
  SMART
  SM00369 (LRR_typ_2)
  
  1,062 - 1,085
  
  SMART
  SM00369 (LRR_typ_2)
  
  865 - 888
  
  SMART
  SM00369 (LRR_typ_2)
  
  1,038 - 1,061
  
  SMART
  SM00369 (LRR_typ_2)
  
  638 - 660
  
  SMART
  SM00369 (LRR_typ_2)

no IPR

Unintegrated signatures

G3DSA:3.10.20.90

387 - 499

GENE3D
G3DSA:3.10.20.90 (G3DSA:3.10.20.90)
SM00364 (LRR_bac_2)

1,086 - 1,105

SMART
SM00364 (LRR_bac_2)

638 - 657

SMART
SM00364 (LRR_bac_2)

661 - 680

SMART
SM00364 (LRR_bac_2)

753 - 776

SMART
SM00364 (LRR_bac_2)

614 - 633

SMART
SM00364 (LRR_bac_2)

842 - 861

SMART
SM00364 (LRR_bac_2)

888 - 907

SMART
SM00364 (LRR_bac_2)
SM00365 (LRR_sd22_2)

638 - 669

SMART
SM00365 (LRR_sd22_2)

1,062 - 1,083

SMART
SM00365 (LRR_sd22_2)

865 - 890

SMART
SM00365 (LRR_sd22_2)

842 - 860

SMART
SM00365 (LRR_sd22_2)

684 - 712

SMART
SM00365 (LRR_sd22_2)

731 - 749

SMART
SM00365 (LRR_sd22_2)

614 - 635

SMART
SM00365 (LRR_sd22_2)

753 - 771

SMART
SM00365 (LRR_sd22_2)
cd00143 (PP2Cc)

1,232 - 1,488

CDD
cd00143 (PP2Cc)
cd01775 (CYR1_RA)

431 - 524

CDD
cd01775 (CYR1_RA)
cd07302 (CHD)

1,558 - 1,727

CDD
cd07302 (CHD)
mobidb-lite (disord...)

174 - 313

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 115

MobiDB Lite
mobidb-lite (disorder_prediction)

366 - 409

MobiDB Lite
mobidb-lite (disorder_prediction)

325 - 350

MobiDB Lite
mobidb-lite (disorder_prediction)

1,527 - 1,549

MobiDB Lite
mobidb-lite (disorder_prediction)

1,939 - 1,972

MobiDB Lite
mobidb-lite (disorder_prediction)

983 - 1,008

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative ras inter...

432C

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

434R

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

442F

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

443G

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

445L

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

446F

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

450D

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

451V

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

459L

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

462K

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

463K

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

465Y

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)

467G

putative ras interaction surface
432C, 434R, 442F, 443G, 445L, 446F, 450D, 451V, 459L, 462K, 463K, 465Y, 467G
CDD
cd01775 (CYR1_RA)
Active site cd00143

1,250D

Active site
1,250D, 1,251G, 1,252R, 1,441K, 1,481D
CDD
cd00143 (PP2Cc)

1,251G

Active site
1,250D, 1,251G, 1,252R, 1,441K, 1,481D
CDD
cd00143 (PP2Cc)

1,252R

Active site
1,250D, 1,251G, 1,252R, 1,441K, 1,481D
CDD
cd00143 (PP2Cc)

1,441K

Active site
1,250D, 1,251G, 1,252R, 1,441K, 1,481D
CDD
cd00143 (PP2Cc)

1,481D

Active site
1,250D, 1,251G, 1,252R, 1,441K, 1,481D
CDD
cd00143 (PP2Cc)
nucleotidyl bindin...

1,563F

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,565D

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,566I

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,567K

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,568N

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,569S

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,570T

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,604K

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,606E

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,607G

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,608D

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,611V

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,684D

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,685Y

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,686F

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,690V

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,691N

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,694A

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)

1,695R

nucleotidyl binding site
1,563F, 1,565D, 1,566I, 1,567K, 1,568N, 1,569S, 1,570T, 1,604K, 1,606E, 1,607G, 1,608D, 1,611V, 1,684D, 1,685Y, 1,686F, 1,690V, 1,691N, 1,694A, 1,695R
CDD
cd07302 (CHD)
metal binding site...

1,565D

metal binding site
1,565D, 1,608D
CDD
cd07302 (CHD)

1,608D

metal binding site
1,565D, 1,608D
CDD
cd07302 (CHD)
dimer interface cd...

1,570T

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,581R

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,584I

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,585K

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,588N

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,592R

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,604K

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,605T

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,673V

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,676T

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,685Y

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,686F

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,687G

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,688P

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

1,691N

dimer interface
1,570T, 1,581R, 1,584I, 1,585K, 1,588N, 1,592R, 1,604K, 1,605T, 1,673V, 1,676T, 1,685Y, 1,686F, 1,687G, 1,688P, 1,691N
CDD
cd07302 (CHD)

Protein sequence

>MIA_06062_1
MPMRSPFELKGASQQSQPPDHRQVLADNLISRPPSPKQQAPPSIYEGCVPISATSSQSSLVNTSHPPSIASSSKRKHRPF
SKLLRKHSNEDDYEEQEPSTPKPKQRVSVRGGGGSAVSQVQYLQLSLQDPSALSTVNTNVSLSTAPSNSSSSLFSASYLE
DDARSIAFPRKVSSGVAGAPTSLVGPNVSGTTSTQTNSSPPVPTTLLGVSQGSSTSSNTTTTTGNPNTNFNTTTNNTSTS
SINSSAPFPSSMPLRKSTTNFSSGNHRPSNVLPTLDTQPPPHKTIHFALNPTEYPQPSPASPPPLSPNTCSPSQFLTIKD
IEDVSPLSSFSGPSKKPHSDSVSSTKTVTGQMDSSVIDQELDQSISHASSVRQNSDPISPLVVPDPDPQSQSTQPQQQTR
ARSTPESWNIVPSFVPGKVSPFPARDPSEKHCVRIFREDDTFGTLFCRVDVTVKELIQLIGKKFYMGSVAGHQLTVRIGG
LTRILNPEETPLVYQSSLLELMGYTEKDRIGEVGREDLSYLCRFKLTRSKIRTVTDNEKAILSRDFSHVQLQHMDLQTIP
VFFYPHASKIEFLDVSENPSISIPSDFIQACHNLREIRYVHNQAYTFPPNVILPPQLGFLDIKDNLIKSLDDVDFLKLSN
LTFIDLQGNLLDHIPDSFSQLQSLRYLNLSSNNIEDFPNAICKIVSLVDFDISFNKIADLPNEIGQLENLEKLAISNSYL
SKRLPDTFVNLVSLKELDLRYNKIQNIDLLARLPKLEVLYVSKNSITSFDAEFPKLKLFYFDRNPITNIDFRGAQSTLTA
INLSKAQMAGVPDALIDRIPLVERLVLDKNHITTLPPKIGMLKNLKYLSVVSNSLDSVPAEIGQLHNLVHLDLHDNNILH
LPSEIWNLSSLVLLNVASNLLDSFPKSPTSHSSISSSDSERREVCAMVSDMLAANSTMPATPEARRPSTLSISSSYDEYK
PQATIKPVNSGAGASANAAAGTATPIIRSPKTSTSTSDSNVYSTGNRRQPSPMALSLLTLILCDNRLTEDCFDELSLLTE
LQILNLSYNDIGEVPYGALRRFSHIVELYLSGNKISSLPGDDLEALQGLQVFHVNSNKLHNLPAELGKIAHLGILDVGSN
ILKYNIHNWPYDWNWRFNHDLKYLNFSGNRRLEVNSPNIPNSSYRREVDMSDFTVLSNIRVLGLMDVTLTALSVPDQSAN
CRVRTYGSEIQSYPYGLADSLGHSNNLSVTDMVLERFRGKDNEIVIGLFDGRGTDIQSGNKVSKLVQETFGSIFQEELKK
LRKEEVVEDALRRAFLNTNKEIGNTILMPTEEVAHTPIGHRSSTAINLEYRDGMTGSCATIVYVADNKLYVANAGDSMAI
IAHVTNEYSVLTTRHDPTSQKELKRIRRSGGIISSTGQLDDLLDVSRAIGFYNLIPHIHASPSVTMWEISDADEMVILAS
KQLWEYVSYQTAVDIARTEKGDLMRAAAKLRDFAIAYGASDKILVMVIGVGLSRKRVRTNKVGAPVYGTNGGDVTVENYD
GTFSRMGDEYSSHKKRRDKGKDSELARLGGEVEPPQGELAIVFTDIKNSTSLWESHAPAMRSAIKLHNGIMRRQMRITGG
YEVKTEGDAFVVSFPTPTSALLWCLNVQQQLLLADWPAEILETEDGCEILDDKGQLMYRGLSVRMGIHWGSPVCETDPIT
RRMDYFGPMVNKAARISAVADGGQISLSSDFVSEMKQIRAALDAVKENKMTLSEVFGGDEVLGWKLEQEMKVLDSIGWEI
KELGEYKLKGLENPEFINLGYPKQLLGRFEHHLLSKKKRSEVRSSRYGSLSLEQLPNLRLCAVRLEHICSSLNPCTTISS
DGAMPPLRAFPNKEPGPTNRTTNQLGIMLPNNEYEYGAFLDNIVTRVENAVTTLTLRTAMDKFKCGSGTAELNELLHQAL
GIISQAGHAGISQASRLQELPQLPPPPPHEHQQQLLTMTPSLSESSFVTAPE

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

Molecular Function

GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0016849 phosphorus-oxygen lyase activity

Cellular Component