Protein

MIA_06037_1

Length
1,498 amino acids

Browser: contig10:54034-58531+

Protein function

EGGNOG:0PFBFFG01204.1GTPase-activating protein
SGD closest match:S000002399LRG1Rho-GTPase-activating protein LRG1
CGD closest match:CAL0000193549LRG1Lrg1p

Protein alignments

%idAln lengthE-value
A0A0J9X785_GEOCN56.522%11960.0Similar to Saccharomyces cerevisiae YDL240W LRG1 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity OS=Geotrichum candidum GN=BN980_GECA03s04938g PE=4 SV=1
UniRef50_A0A0J9X78556.522%11960.0Similar to Saccharomyces cerevisiae YDL240W LRG1 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X785_GEOCN
MCA_05216_174.198%6550.0MCA_05216_1
A0A060TDS4_BLAAD52.244%5574.14e-177ARAD1D46398p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D46398g PE=4 SV=1
A0A167F0R4_9ASCO51.769%5371.44e-168Lrg1p OS=Sugiyamaella lignohabitans GN=LRG1 PE=4 SV=1
Q6C1U9_YARLI43.144%5477.06e-131YALI0F13211p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13211g PE=4 SV=1
A0A1E3PN49_9ASCO44.031%5111.37e-124RhoGAP-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7663 PE=4 SV=1
A0A1D8PRQ6_CANAL41.143%5255.42e-118Lrg1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LRG1 PE=4 SV=1
A0A1E4TBD6_9ASCO41.098%5284.79e-116Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58101 PE=4 SV=1
LRG1_YEAST42.742%3721.08e-77Rho-GTPase-activating protein LRG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LRG1 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0093
Predicted cleavage: 97

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1498

Detailed signature matches

  1. Domain IPR001781
    Zinc finger, LIM-type
    1. PF00412 (LIM)
    2. PS50023 (LIM_DOMAIN_2)
    3. PS00478 (LIM_DOMAIN_1)
    4. SM00132 (lim_4)
  2. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  3. Domain IPR000198
    Rho GTPase-activating protein domain
    1. SM00324 (RhoGAP_3)
    2. PF00620 (RhoGAP)
    3. PS50238 (RHOGAP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.55...
  2. G3DSA:2.10.11...
  3. SSF57716 (Glucocort...)
  4. cd09391 (LIM1_Lrg1p...)
  5. cd09392 (LIM2_Lrg1p...)
  6. mobidb-lite (disord...)

Residue annotation

  1. Zn binding site cd...
  2. Zn binding site cd...

Protein sequence

>MIA_06037_1
MATSPSPALSSRDSYPPAAIKQPTVAQQELLMNTQNISHKVSQLPSGSIPASPAQSPSKPTLSLNTTSPLTSQQTHPCLK
EQHPAFRPLPNCCHHQNTHHHHHAHSYSGLPSPDTFYTPAEPAPPVVSVCRPQATRSVNFSRPSAHHTHSTDGQHSPTEL
LSSCSSFQPPPVPSLNPPPKFRGPQASYHRRFSLRKPDDVTNPAHPPKPTPSSDAPATLYRSVSVSPQMTHPAVAPGTTP
PPSSSSASSASSSSFSSTTITTATTLSSLPPEAVQVSADRHKSMAVVTDGRPLDDDDDGNANTNNNSGDGNNNNNNNINN
NNTNNNNNNNNNNNNNNNEKPKRQPKYCFKCKKPIPGHFVRALGCIYHMECFCCYDCNNQCSAKFFPVEAPMEIPETNNL
IPLCEHDYFGRQDLLCCVCDGALRGSYITALGKKYHVEHFTCSLCSTVFGNDDSYYEHEGSIFCRFHYSTLYAANCEGCK
TAILKQFVELFRGGREQQWHPECYMINKFWNVMISPTRLHVYDKQDSKESLDVPKSPNPETRELVLNTEQEAERKAFHIW
SVLCGYEEATAACISDMLQFATSSRYNDALLATARLVAKIEVLLSAIDILIAHVDPLLSALRSIDESLPEELADEDPEFL
NLIEIVRNAGFTQLHKEPKTLCKKVVSFMSLLSKSRDRSVKTSGISHELLDSVTSMAHYLKLLIRYGLSNSLRYDRAFPS
GNLVAIFLDKVATHDQIPANPLETLSISGKANDKCLACEDSTEDDCAVLDDNKLWHLDCLACSKCHKPLGSCVKDARYLT
KEKVVVCTSCLKLDDECLDNFVVVTKLNQFIYLVKIALARLRLVLKSYDKRDANKAAAAAAAAAAAATITAPPPLRIQDS
RPVMSPRRSSNSVPLVSSTSGSSSCSKGKTSSSSSSSSSSKAPPPSDNYMTTLKDIRKLRSTRLSQRLSESSRRARRSRI
LDIPDSEHGLLGKNDSSTSLPSPQQQSPQQLVKMHNQGMPSRVPEAKEDNILENVPMESSPPSGFSKSRGRKFSSGSRRR
RVKIEEDPINREYTQLDRTTDLLKSEKSLILDDIPRIVAAEQARELRPNAYRHRRQELNTDEDVPVQDVHEKKPVAEKFM
SDLTPEEQFIVRHIAVSLLQPLVAGWYSLEELCDIIGVRKAPSLWDKFNKAFSLNDRSAAEDKRRPRKTGVFGVSLEQQV
EQYGVDSSFGVGPNPLRIPAFVDECISAMRQMDMSVEGVFRKNGNIRRSKELATMVDNNPDYAGLFTDENPIQLAALFKR
YLRELPDSLMTFKLQKLWVMSQEIADVEERVRVMHLGCCVLPGAHRDVMEVLFYFLYWTASFSHIDEESGSKMDIHNLST
VITPNILYTRKRENGQADSSEGYFLAIEAVNTLIQEYDRFAKVPAEVLEVLEGGFGEEGTSPNSSASGTSNGTVNLPSKE
IFARIEQYRANQGLAVPGAISVAAVSREAPSTATDGGLVAVRQTVSGGNNGTSAEDGE

GO term prediction

Biological Process

GO:0007165 signal transduction

Molecular Function

None predicted.

Cellular Component

None predicted.