Protein

MCA_05216_1

Length
2,088 amino acids


Browser: contigD:647073-653340-

RNA-seq: read pairs 1770, FPKM 10.5, percentile rank 26.7% (100% = highest expression)

Protein function

EGGNOG:0PFBFFG01204.1GTPase-activating protein
SGD closest match:S000002399LRG1Rho-GTPase-activating protein LRG1
CGD closest match:CAL0000193549LRG1Lrg1p

Protein alignments

%idAln lengthE-value
MIA_06037_174.57%6450.0MIA_06037_1
A0A0J9X785_GEOCN55.77%7100.0Similar to Saccharomyces cerevisiae YDL240W LRG1 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity OS=Geotrichum candidum GN=BN980_GECA03s04938g PE=4 SV=1
UniRef50_A0A0J9X78555.77%7100.0Similar to Saccharomyces cerevisiae YDL240W LRG1 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X785_GEOCN
A0A060TDS4_BLAAD52.57%5445e-168ARAD1D46398p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D46398g PE=4 SV=1
A0A167F0R4_9ASCO47.78%6534e-162Lrg1p OS=Sugiyamaella lignohabitans GN=LRG1 PE=4 SV=1
Q6C1U9_YARLI41.44%5553e-121YALI0F13211p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13211g PE=4 SV=1
A0A1D8PRQ6_CANAL41.29%5283e-119Lrg1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LRG1 PE=4 SV=1
A0A1E3PN49_9ASCO43.33%5174e-120RhoGAP-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7663 PE=4 SV=1
A0A1E4TBD6_9ASCO39.35%5541e-111Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58101 PE=4 SV=1
LRG1_YEAST31.56%5072e-73Rho-GTPase-activating protein LRG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LRG1 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0196

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1800 2088

Detailed signature matches

    1. PF00412 (LIM)
    2. PS50023 (LIM_DOMAIN_2)
    3. PS00478 (LIM_DOMAIN_1)
    4. SM00132 (lim_4)
    1. SSF48350 (GTPase ac...)
    1. SM00324 (RhoGAP_3)
    2. PF00620 (RhoGAP)
    3. PS50238 (RHOGAP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF57716 (Glucocort...)
  2. cd09391 (LIM1_Lrg1p...)
  3. cd09392 (LIM2_Lrg1p...)
  4. mobidb-lite (disord...)

Residue annotation

  1. Zn binding site cd...
  2. Zn binding site cd...

Protein sequence

>MCA_05216_1
MQNPSGKSSLMTSTSQQQQQQQPPQQQQSQQQHQILSSSSSSSTLKIQNSTENNSNSPIQSPRQPDNSNNPQLNQHSSLY
STKEQDENSQTNNLMSNNNSNNNTTKPSPHHTYSHSFGHIALHHHHHHHNDEPKSPQLFSPIPQKSDIHGNNNKNINEPS
LEISSELAQSKSHSPQPQSSADTSPTEEHTKNPSLQRYRNNHMHLHLHQQQQPDYSKVPHRSLSPPTFIHSRPSSRGSGV
NFSRPSTFYKLENISPLDSPTGQIPMPSSTTSATFHGHPLSPALRQNSFSSSNSSEDNFYSPGTSPVKPVHQDPHSQKHF
TTSTSALDNAGVEKNGIILDSSFPSRNISSSSATTSSSSSSTSSVSSKSSKKEFESGSDRLNANASFSYLPSFQQNQPLR
RSSDLLLTRHASFSSYPRKSAQQQQQQQQQQQQQQQQTHSRSFSIRRVDTNSSFQSLNNQDPFDDSLQPPIIKSASNQSL
PASPTTILYPPPAPPLSQIRIASDPLHNNTTTTNSNITHNNFHHNSDTATTTTSTTNQSNPTTTSSSTPNWQAFIASQQN
MKPRQQSYSSESTNQIVSSNSSSSDYKNNNASQTDTNTLKYKQSNNIDSSPFNKTPTMTPQHSGRSNLQNNDSIHPSSSH
NLDPTSTKSSSSSDSIEQETSSQSITIKSQVIDKHKSVAVLTGTIDDITEPVPMPPTDYIYQNGTNDPSISSNTNNVIQV
SSQSTNSSLSPSNKQQQQQQQQQIDDNNDSNQTNEDTTLGRENNEDKSLVKPKKKQKTCFTCKQPISGHFVRALGCIYHM
ECFCCYDCGTQCSAKFFPFESPTEIPETNNVIPLCEHDYFRRQDLLCCVCDSALRGSYITALGKKYHVEHFTCSLCSTVF
GTDDSYYEHEDNIYCRYHYSTLYAAKCEGCKTAILKQFVEVFRGGREQQWHPECYMINKFWNVMISPTKLKVYENDDQLL
ITKEETFSNNKQITNGIDFDKPLASPDAETRERVLQTEQEAEKKAFHIWSVLCGYEEASAACISDMLQYATSSRFNDALL
ATARLVAKIEVLLSAIDTLVAHIDPLLSALSSIEESTPEELAEETPEFLNLMEIVRNAGFTQLRKEPKTLCKKIVSYMSI
LSKSRDKSITEPGPSHDLLDSVTSMAHYLKLLIRYGLSNSLRYDRAFETGNLVVTFLDKVATHDQIPANPLETLSVSGKA
NDKCLKCDDSTEDDCAILDDNKLWHLDCLACSRCQKALGSIVKDARYIPAEKAVVCKSCLRPTDEFVDGFVVVTKLNQFI
YLVKIALARLQLVLKTFDKRDASKSVTSSVGSAKPQQRPQLESRKSGNVVLTTEPSQPLSPSKNLHTTASQTSTASHTTG
STNAADSNYMTTLKDIRKLRSTRLSKRLSESSRRARRSRILDIPDSEHGLLGKNDSSTSLPNHGEPQTPQQIAKSHSNYY
NPLQQQHQLQQIHQQQQQLQPHSTASSINQGLKPPSSTGSSSRRGSTSKDGYILDVVTSGDEMVSSPPSNKDSFSKPSSQ
QRSNNQSSVSTVPSGPSSGSSFSKGGKGKKFGGPKRRRKLTIEEDPINNKPGYSQLDRTTDLLKSDKSLILDDIPRIVAA
EQARELRPNAYRHHQQDRSADEDVTVQNVSRKKSTDKYISALTPQESFLVRHIALALLYPLVSQWYSMDDLLELIEVRKA
PSIWEKFGKALNLNGGDRSASSDQKKKKTGVFGVSLEQQVENYGVDSTFGVGLTPLKIPAFVDECISAMRQMDMSVEGVF
RKNGNIRRSKELATLVDNNPDYAGLFTDENPIQLAALFKRYLRELPDSLMTFKLHKLWVNSQEISDINERIRLMHLACCI
LPPAHRDVMEVLFFFLFWTASFSHIDEESGSKMDIHNLSTVITPNILYANRKESSSPESSEGYFLAIEAIDILIKEYDRF
SKVPAEVLDILQNEFMKNNNPTELSQLTSKEIFSRIEQYRAKNPYNGPSNDAYRSSSISSTVDPRSYNDSKNPLGLIKNE
DTNNNNNNNSNNNNNINKDGNDDDMSDDDNSRSASPAGGTLATTQLPTMVIPLPSNAQINKSLPPTPKDSDFEGNSSIKS
SVTLTKEK

GO term prediction

Biological Process

GO:0007165 signal transduction

Molecular Function

None predicted.

Cellular Component

None predicted.