Protein

MIA_05982_1

Length
267 amino acids


Browser: contig09:890411-891264-

Protein function

EGGNOG:0PINWPOL30This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity)
SGD closest match:S000000292POL30Proliferating cell nuclear antigen
CGD closest match:CAL0000174634POL30Proliferating cell nuclear antigen

Protein alignments

%idAln lengthE-value
MCA_03601_166.275%2551.28e-132MCA_03601_1
A0A0J9X4H9_GEOCN58.366%2571.27e-116Proliferating cell nuclear antigen OS=Geotrichum candidum GN=BN980_GECA02s05334g PE=3 SV=1
UniRef50_A0A0J9X4H958.366%2572.61e-113Proliferating cell nuclear antigen n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X4H9_GEOCN
A0A1E3PF65_9ASCO53.696%2571.46e-103Proliferating cell nuclear antigen OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_37443 PE=3 SV=1
A0A060T0G1_BLAAD51.550%2581.61e-97Proliferating cell nuclear antigen OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07392g PE=3 SV=1
Q6C9K1_YARLI48.235%2559.19e-90Proliferating cell nuclear antigen OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D10571g PE=3 SV=1
Q5AMN0_CANAL42.248%2586.40e-80Proliferating cell nuclear antigen OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=POL30 PE=3 SV=1
PCNA_YEAST43.580%2573.12e-79Proliferating cell nuclear antigen OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POL30 PE=1 SV=1
A0A167DE24_9ASCO47.482%1395.72e-44Proliferating cell nuclear antigen OS=Sugiyamaella lignohabitans GN=POL30 PE=4 SV=1
A0A1E4TD23_9ASCO26.894%2642.37e-36Proliferating cell nuclear antigen OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4296 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2044

Protein family membership

Domains and repeats

1 50 100 150 200 267

Detailed signature matches

    1. MF_00317 (DNApol_cl...)
    2. PR00339 (PCNACYCLIN)
    1. PF00705 (PCNA_N)
    1. PF02747 (PCNA_C)
    1. PS01251 (PCNA_1)
    2. PS00293 (PCNA_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF55979 (DNA clamp)
  2. cd00577 (PCNA)

Residue annotation

  1. putative DNA bindi...
  2. PCNA/WAF1-CIP1 pro...
  3. PCNA/FEN-1 protein...
  4. trimer interface c...
  5. PCNA/RFCL protein ...

Protein sequence

>MIA_05982_1
MFEAKLTEASIFKKIVESVKDGFKNCNFDCSEEGISMESMDDAHIALVSMKLGVETFSSYRCDRSISLGLNIESLLKVLR
TANNNDVLTMRAEDDGDLLTLVFEDASNPDRISEYNLKLLNIDQEHMSIPEQEYTATVTLPSAEYQRIIRDLTQLGDSIT
IDAAKDGVRFTAEGDIGSGSVSLKANTNIGEDEKSIDIAVEEPVALSFNSKYLTQTCKAGALAPRVSLNLCKRIPIFISY
KLQAGHFSFFLAPQISEGDDEEDDDED

GO term prediction

Biological Process

GO:0006275 regulation of DNA replication

Molecular Function

GO:0003677 DNA binding
GO:0030337 DNA polymerase processivity factor activity

Cellular Component

None predicted.