Protein

MIA_05971_1

Length
788 amino acids

Browser: contig09:853610-855977+

Protein function

EGGNOG:0PGDCMKK1MAP kinase kinase
SGD closest match:S000005757MKK1MAP kinase kinase MKK1/SSP32
CGD closest match:CAL0000192384MKK2Mitogen-activated protein kinase kinase

Protein alignments

%idAln lengthE-value
MCA_02361_192.283%3110.0MCA_02361_1
A0A167F1P1_9ASCO79.939%3290.0Putative mitogen-activated protein kinase kinase MKK2 OS=Sugiyamaella lignohabitans GN=MKK2 PE=4 SV=1
A0A0J9X7Z1_GEOCN84.839%3100.0Similar to Saccharomyces cerevisiae YOR231W MKK1 Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity OS=Geotrichum candidum GN=BN980_GECA04s06764g PE=4 SV=1
A0A060T1I8_BLAAD80.782%3073.80e-179ARAD1C25014p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C25014g PE=3 SV=1
A0A1E3PDP9_9ASCO80.386%3111.95e-175Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47947 PE=4 SV=1
Q6CET2_YARLI79.487%3121.76e-172YALI0B13178p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13178g PE=4 SV=1
UniRef50_Q6CET279.487%3124.07e-169YALI0B13178p n=6 Tax=Saccharomycetales TaxID=4892 RepID=Q6CET2_YARLI
A0A1E4TMI5_9ASCO76.547%3073.59e-166Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30947 PE=3 SV=1
MKK1_YEAST63.924%3162.01e-129MAP kinase kinase MKK1/SSP32 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MKK1 PE=1 SV=1
A0A1D8PHG7_CANAL52.667%3001.33e-97Mitogen-activated protein kinase kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MKK2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2680

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 788

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd06621 (PKc_Pek1_like)
  4. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd06621
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MIA_05971_1
MSSQFPSLIPPQTSSQRKYPSLAIPKSPASSQSPASSSSSLQTPIPVPYASSTPPSATIPTLATSPAINPIDLTAAPPPS
RTDPSPSGGLFSPEIYAALGMKTPVPSAQAPLTAPTTFISVPHKQQPSPLGPIDAPTYTPNILTAASAPPQSSSQGLSLS
TLSINDNPTTPQPSLSSIASSIKPPAVPQQFPLPSSPSLPPDLNPGPLPANSNNPFLSIINPPPSAEQQPSLTINPPQIS
TRVSNPSYNEDINVNLNNINPTYTPPSAPIPSTLSPFPFPVKKSASKTILTSLAIPTNPNAPAPKTYTAVSYQNPPSLSQ
DSLLQQPPSSTIFNRHHHSSSSSSSSTITSTSEASSSLSVPSSDLSQTCDPFIPPVKPPPSPKHPSIFLDTTKVKATASQ
RDPNDNPSLKIEDTLVLTIERKKTASPSPSSMSSPPSNSSSSTDLTAAITSTTIEPPNDLIPTSTSTPHFDKNYNDHYAQ
LDVADLDEDGWRAVAEAGDIEELGKLGEGAGGSVTRCRLKNRGPNSKVFALKAITTNPNPEVQKQILRELQFNRTCNSPH
IVKYFGTFLSEETASIFIAMEYCGGGSLEAIYKRVKARDGRIGEKVLGKIAEGVLSGLSYLHERKIIHRDIKPQNILLDS
EGQVKLCDFGVSGEVVNSLATTFTGTSYYMAPERIQGQPYTVTSDVWSLGLTIMEVAQHRFPFLPENHEPLTPIELLSVI
VNMPAPELKDEPDEGIKWSESFRHFLKSCLEKDPKKRASPRQMLMHPWIVGQRNKSVKMAKFVKECWS

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.