Protein
MCA_02361_1
Length
962 amino acids
Gene name: MKK1
Description: MAP kinase kinase MKK1/SSP32; in S. cerevisoae involved in the protein kinase C signaling pathway and control of cell integrity.
Browser: contigB:1056864-1059753-
RNA-seq: read pairs 2182, FPKM 28.0, percentile rank 50.6% (100% = highest expression)
Protein function
| Annotation: | MKK1 | MAP kinase kinase MKK1/SSP32; in S. cerevisoae involved in the protein kinase C signaling pathway and control of cell integrity. | |
|---|---|---|---|
| KEGG: | K08294 | MKK1_2 | mitogen-activated protein kinase kinase [EC:2.7.12.2] |
| EGGNOG: | 0PGDC | MKK1 | MAP kinase kinase |
| SGD closest match: | S000005757 | MKK1 | MAP kinase kinase MKK1/SSP32 |
| CGD closest match: | CAL0000192384 | MKK2 | Mitogen-activated protein kinase kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05971_1 | 92.28% | 311 | 0.0 | MIA_05971_1 |
| A0A0J9X7Z1_GEOCN | 86.22% | 312 | 0.0 | Similar to Saccharomyces cerevisiae YOR231W MKK1 Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity OS=Geotrichum candidum GN=BN980_GECA04s06764g PE=4 SV=1 |
| A0A167F1P1_9ASCO | 84.97% | 306 | 0.0 | Putative mitogen-activated protein kinase kinase MKK2 OS=Sugiyamaella lignohabitans GN=MKK2 PE=4 SV=1 |
| A0A060T1I8_BLAAD | 80.70% | 316 | 0.0 | ARAD1C25014p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C25014g PE=3 SV=1 |
| A0A1E3PDP9_9ASCO | 80.97% | 310 | 0.0 | Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47947 PE=4 SV=1 |
| Q6CET2_YARLI | 79.17% | 312 | 6e-178 | YALI0B13178p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13178g PE=4 SV=1 |
| UniRef50_Q6CET2 | 79.17% | 312 | 1e-174 | YALI0B13178p n=6 Tax=Saccharomycetales TaxID=4892 RepID=Q6CET2_YARLI |
| A0A1E4TMI5_9ASCO | 75.90% | 307 | 1e-161 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30947 PE=3 SV=1 |
| MKK1_YEAST | 64.94% | 308 | 6e-135 | MAP kinase kinase MKK1/SSP32 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MKK1 PE=1 SV=1 |
| A0A1D8PHG7_CANAL | 52.00% | 300 | 1e-99 | Mitogen-activated protein kinase kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MKK2 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.6883
Predicted cleavage: 40
Protein family membership
None predicted.
Domains and repeats
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Domain
1
100
200
300
400
500
600
700
800
900
962
Detailed signature matches
no IPR
Unintegrated signatures
-
-
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cd06621 (PKc_Pek1_like)
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mobidb-lite (disord...)
Residue annotation
-
ATP binding site c...
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active site cd06621
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polypeptide substr...
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activation loop (A...
Protein sequence
>MCA_02361_1 MYHSPNPTNIIKSPVSATKSRFPSLSIPQSPSVGPISRPDGTVVIASPSIDSSLINYISSSSKNLFNSLENNSQTTLSSN INNNPPESAVSTCSNLSTCSNSIYTCDSSSSSVVITSSDLSNNSSSNNNNINSNKNKLSTLSSSSSSSLSSSSTKPYDNF ITMKNSLDHSVVESESSINISNAEPVPTKSATTTISSNNTVPGGPSIPPCIPVPSSQQQRKPQLTMNTFIQNPSDSSFSS SSFNNTTNNTLGMSSSNSTSSTSSSTPSSTTISNIDNDTNNSTSTLVNPLTSINNSSSSSITNNTNNNKTQQPSLHTSYS SLPNHFNQLNIQTSTQQSTNLKLSIPSIEVPSPDKSETIKSTPNLSLNVSVNKSTTNDLSTTIPFPDYSNSSTITSSSST TSSSSTTANLSASPFPFPVRKSPSKSFLTSLSIPTNPNIPQKSYVPVPETCQKPSYYHHQPTSSSSSSSSYSDDSFHSTS NPSSTHSSTTPSKLLVNTSSLFPTENENLMIPTETSGGFTTDKTITAISYASSYTNSNSVISSTSCENITNESLSLQLNT GTKAASSGQITYIGPSTTSNGTINNLESSNNISSTPQPTDSNGTLSNEYTSSSSRIPDLPQSSFSASYSSFSSTYSSAPT PMVGFPPKYAKYANVDVQDLDEEGWQIVAAAGDIEQLGRLGEGAGGSVTRCRLKHRGPASKVFALKTITSNPNPEVQKQI LRELQFNRTCNSPHIVKYYGTFLSEETASIFIAMEYCGGGSLEAIYKRVKARGGRIGEKVLGKIAEGVLSGLSYLHERRI IHRDIKPQNILLDSQGQVKLCDFGVSGEVVNSLATTFTGTSYYMAPERIQGQPYTVTSDVWSLGLTIMEVAQHRFPFLPE NHEPLMPIELLSVIVNMPAPELQDEPEEGIKWSDSFRHFLKSCLEKDPQKRASPRQMLGHPWIVGQRNKTVKMAKFVKEC WS
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.