Protein

MIA_05967_1

Length
533 amino acids

Browser: contig09:846229-847831+

Protein function

EGGNOG:0PFQTMSS1tRNA modification GTPase
SGD closest match:S000004625MSS1tRNA modification GTPase MSS1, mitochondrial
CGD closest match:CAL0000188182orf19.2042Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_02359_163.504%5480.0MCA_02359_1
A0A0J9X666_GEOCN59.041%5420.0Similar to Saccharomyces cerevisiae YMR023C MSS1 Mitochondrial protein, forms a heterodimer complex with Mto1p OS=Geotrichum candidum GN=BN980_GECA04s01968g PE=3 SV=1
UniRef50_A0A0J9X66659.041%5420.0Similar to Saccharomyces cerevisiae YMR023C MSS1 Mitochondrial protein, forms a heterodimer complex with Mto1p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X666_GEOCN
A0A1E3PDT2_9ASCO52.601%5194.46e-178Mitochondrial protein, forms a heterodimer complex with Mto1p OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71806 PE=3 SV=1
A0A060T7V2_BLAAD51.197%5432.84e-171ARAD1C24948p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C24948g PE=3 SV=1
A0A170QYB0_9ASCO48.571%5256.81e-157Mss1p OS=Sugiyamaella lignohabitans GN=MSS1 PE=3 SV=1
Q6CE47_YARLI48.069%5181.03e-148YALI0B18612p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B18612g PE=3 SV=1
A0A1D8PG79_CANAL41.634%5141.51e-133Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2042 PE=3 SV=1
MSS1_YEAST41.101%5454.22e-126tRNA modification GTPase MSS1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSS1 PE=1 SV=2
A0A1E4TBZ0_9ASCO37.595%5241.04e-96Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58244 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9635
Predicted cleavage: 42

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 500 533

Detailed signature matches

  1. Family IPR004520
    tRNA modification GTPase MnmE
    1. MF_00379 (GTPase_MnmE)
  2. Domain IPR018948
    GTP-binding protein TrmE, N-terminal
    1. PF10396 (TrmE_N)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR025867
    MnmE, helical domain
    1. PF12631 (MnmE_helical)
  5. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
  6. Domain IPR006073
    GTP binding domain
    1. PF01926 (MMR_HSR1)
  7. Domain IPR031168
    TrmE-type guanine nucleotide-binding domain
    1. cd04164 (trmE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.12...
  2. G3DSA:3.30.13...

Residue annotation

  1. G1 box cd04164
  2. GTP/Mg2+ binding s...
  3. Switch I region cd...
  4. G2 box cd04164
  5. Switch II region c...
  6. G3 box cd04164
  7. G4 box cd04164
  8. G5 box cd04164

Protein sequence

>MIA_05967_1
MPFLKAFQTRCYSHLPRTSYLPTIYALSTKPGKAAIAIVRVSGTRAKDVYKLLTRRIKDPTPRSVIYSTLYNPTAPTKSP
AAVLDHAVVLYFQAPHSYTGEDVLELQLHGGNAIVRSVLSALHLLGKTDAVTSQQQSKLNLGLRYAEAGEFSKRAFQNGA
LDLTQIEGIRDSIDAETETQRQAALASSSGHLKRQYDSWRSQIVDSMALLTALIDFSEDSGDVGESASVLFTQAREKVAA
LLTEIGRHRSQIQKSQLIMDGIKLDLLGPPNAGKSYLLNRLAEREAAIVSDVPGTTRDVLEVPMDIGGYKLVLGDTAGLR
NHEHLKNTTDATSTETSIAHSAMRIEMEGIRRARERFKSSDIILAVVPASPTLEIPVDVAQEIRALEGKRIIVVLNKEDL
LDSSADKSLLVEAYAAQLRVPSKHIILTSCVTTSGINELVSAIESECQDLVQSGDDTGSQLPPVAASQRVRDILDHEVVA
GLENFMAIEDERDVVIATEELRFAAEGIGKITGQGVGIEEVLGVVFGNFCIGK

GO term prediction

Biological Process

GO:0006400 tRNA modification

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0005622 intracellular