Protein

MCA_02359_1

Length
558 amino acids

Gene name: MSS1

Description: tRNA modification GTPase MSS1, mitochondrial

Browser: contigB:1051385-1053141+

RNA-seq: read pairs 865, FPKM 19.1, percentile rank 40.3% (100% = highest expression)

Protein function

Annotation:MSS1tRNA modification GTPase MSS1, mitochondrial
KEGG:K03650mnmE tRNA modification GTPase [EC:3.6.-.-]
EGGNOG:0PFQTMSS1tRNA modification GTPase
SGD closest match:S000004625MSS1tRNA modification GTPase MSS1, mitochondrial
CGD closest match:CAL0000188182orf19.2042Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_05967_163.87%5480.0MIA_05967_1
A0A0J9X666_GEOCN57.22%5330.0Similar to Saccharomyces cerevisiae YMR023C MSS1 Mitochondrial protein, forms a heterodimer complex with Mto1p OS=Geotrichum candidum GN=BN980_GECA04s01968g PE=3 SV=1
UniRef50_A0A0J9X66657.22%5330.0Similar to Saccharomyces cerevisiae YMR023C MSS1 Mitochondrial protein, forms a heterodimer complex with Mto1p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X666_GEOCN
A0A1E3PDT2_9ASCO50.85%5295e-171Mitochondrial protein, forms a heterodimer complex with Mto1p OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71806 PE=3 SV=1
A0A060T7V2_BLAAD46.24%5582e-156ARAD1C24948p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C24948g PE=3 SV=1
A0A170QYB0_9ASCO43.90%5492e-144Mss1p OS=Sugiyamaella lignohabitans GN=MSS1 PE=3 SV=1
Q6CE47_YARLI43.81%5251e-133YALI0B18612p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B18612g PE=3 SV=1
A0A1D8PG79_CANAL41.50%5478e-130Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2042 PE=3 SV=1
MSS1_YEAST40.97%5595e-129tRNA modification GTPase MSS1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSS1 PE=1 SV=2
A0A1E4TBZ0_9ASCO36.64%5542e-102Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58244 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9936
Predicted cleavage: 53

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 558

Detailed signature matches

  1. Family IPR004520
    tRNA modification GTPase MnmE
    1. MF_00379 (GTPase_MnmE)
  2. Domain IPR018948
    GTP-binding protein TrmE, N-terminal
    1. PF10396 (TrmE_N)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR025867
    MnmE, helical domain
    1. PF12631 (MnmE_helical)
  5. Domain IPR006073
    GTP binding domain
    1. PF01926 (MMR_HSR1)
  6. Domain IPR031168
    TrmE-type guanine nucleotide-binding domain
    1. cd04164 (trmE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.12...
  2. G3DSA:3.30.13...
  3. SSF116878 (TrmE con...)

Residue annotation

  1. G1 box cd04164
  2. GTP/Mg2+ binding s...
  3. Switch I region cd...
  4. G2 box cd04164
  5. Switch II region c...
  6. G3 box cd04164
  7. G4 box cd04164
  8. G5 box cd04164

Protein sequence

>MCA_02359_1
MFKFMVRLSKAQLLRSQVRFYSSSFSPVTSYLPTVYALSTRPGKAAIAVIRVTGSQCKSIYKLLTKRSKDPVPRSVLYST
IYDPRKSHKSQETILDKCVILYFQGPHSYTGEDVLELQLHGGNAIVRSVLSALHYLSTNKTSTSFINEEGESQALRYAEA
GEFSLRAFQNGVFDLTQIEGIRDSIDAETEMQRQATLAGSNGLLKEKYESWRNEIVDSMALLTALIDFSEDSGDVAESAS
ELFTQARHKMTSLLSEIKSHQDKVQRSKKLLVDGIKLDLLGPPNAGKSFLVNRLVEKDTAIVSDVPGTTRDILEVPIDIG
GFKLVMGDTAGLRKHESFVKSIDSEIDSEEKSENSVAMSAMKIEMEGIRRAKARFKNSDIILTVIPLSEDSTTLPTISND
IIEEVQTLKSMGKNIIAVLNKSDLLKDDSSQQLKDYVAQKLDISSESIILTSCTKNKGIDQLVDRIESLCKYLYSQGNAG
SDSEDSQPISASQRTMDLLQNDVIAGIENFLSIEDENDVVIATEELRFAAEGIGKITGQGVGIEEILGVVFSSFCIGK

GO term prediction

Biological Process

GO:0006400 tRNA modification

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0005622 intracellular