Protein

MIA_05961_1

Length
701 amino acids

Browser: contig09:820059-822468+

Protein function

EGGNOG:0PFE5BRF1transcription factor TFIIIB complex subunit Brf1
SGD closest match:S000003478BRF1Transcription factor IIIB 70 kDa subunit
CGD closest match:CAL0000177227TDS4Transcription factor IIIB 70 kDa subunit

Protein alignments

%idAln lengthE-value
MCA_00881_156.206%4271.78e-159MCA_00881_1
A0A0J9XJK6_GEOCN53.571%3086.85e-115Similar to Saccharomyces cerevisiae YGR246C BRF1 TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB OS=Geotrichum candidum GN=BN980_GECA24s00131g PE=4 SV=1
UniRef50_A0A0J9XJK653.571%3081.40e-111Similar to Saccharomyces cerevisiae YGR246C BRF1 TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJK6_GEOCN
A0A167D3M9_9ASCO50.338%2961.13e-93Transcription factor TFIIIB subunit BRF1 OS=Sugiyamaella lignohabitans GN=BRF1 PE=4 SV=1
A0A060T3V2_BLAAD47.561%3284.06e-90ARAD1A19162p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A19162g PE=4 SV=1
A0A1E4TLF8_9ASCO43.333%3001.06e-83Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30706 PE=4 SV=1
Q6C4S8_YARLI41.399%3431.56e-79YALI0E24035p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E24035g PE=4 SV=1
TF3B_YEAST44.674%2917.27e-75Transcription factor IIIB 70 kDa subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BRF1 PE=1 SV=1
TF3B_CANAL39.067%3431.07e-73Transcription factor IIIB 70 kDa subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TDS4 PE=3 SV=1
A0A1E3PMX6_9ASCO60.417%961.01e-32BRF1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45981 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0353

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 701

Detailed signature matches

  1. Family IPR000812
    Transcription factor TFIIB
    1. PR00685 (TIFACTORIIB)
  2. Domain IPR013763
    Cyclin-like
    1. G3DSA:1.10.47...
    2. SSF47954 (Cyclin-like)
    3. SM00385 (cyclin_7)
    4. cd00043 (CYCLIN)
  3. Domain IPR013150
    Transcription factor TFIIB, cyclin-like domain
    1. PF00382 (TFIIB)
  4. Domain IPR011665
    Brf1, TBP-binding domain
    1. PF07741 (BRF1)
  5. SITE IPR023486
    Transcription factor TFIIB, conserved site
    1. PS00782 (TFIIB)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.5.650
  3. mobidb-lite (disord...)

Residue annotation

  1. binding site 1 cd0...
  2. binding site 2 cd0...
  3. binding site 1 cd0...
  4. binding site 2 cd0...

Protein sequence

>MIA_05961_1
MDGRKCKSCGSRLDGGVCTQCGLVWEESTMVNDLTFGESSSGAAVVNGSFVSAEQSGPGRGGLYGNSNGREVTIEKARNR
IYGVAHYLRIPEPAIQAAIANFKLALSMNFIRGRKSKYVTCACLYLGCRIQHTSHMIMEFATFLKVNVYILGNTYSQLLR
LLRPMLGSEQLRRVVTIDPTIYIVKFINRLNFASEDSKKVNEDAFRLIKRMDKDWMAMGRRPGGIAAASILIACRMNNLK
RSKAHIMQIAMISESTIDKRLKEFKATVAGTLSVKDFRATNVESSADPPSFLKNRDMERTKNSLQLLANESEKGDDDNDG
VSSNAEDDFEKYTEEDILEMAEEARQLYQDKDEEEDENGNLPPLEKSFEDRSLGRATLYAIEAAKAEVKRIEERRQKRLE
AKLRQGIVHDGDEENGEEKEEDEDSEGDEGQEKKKSEEDQEVEEEENGTTKDEAEEEEKDNSENEEKSEETKITQVETPK
SDEEKSDEEKSDDENPNKETDKKDLEHESQPGSTDEPSTKRRKLTRQERIDAILRRHNHPLVRMASRDTADAAPESQSKT
WVSKISDDPENLSDVDDDELDRVICSETEVARRQRLWVSLNHDYELDQARRRNKIESDKRAGVYKEPRKRRAAQSRFGWG
NRALGSQQYKQEEDGDGSSGSMNARSVAVNMMMERSKMLKVSKKSKKINYGALDGLLNLGN

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0070897 DNA-templated transcriptional preinitiation complex assembly

Molecular Function

GO:0017025 TBP-class protein binding

Cellular Component

None predicted.