Protein

MIA_05930_1

Length
598 amino acids

Browser: contig09:741619-743416+

Protein function

EGGNOG:0QDYJFG02865.1resistance protein
SGD closest match:S000000212FLR1Fluconazole resistance protein 1
CGD closest match:CAL0000173998MDR1Multidrug resistance protein 1

Protein alignments

%idAln lengthE-value
MCA_01586_159.968%6170.0MCA_01586_1
A0A0J9XL11_GEOCN53.512%5980.0Similar to Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter of the major facilitator superfamily OS=Geotrichum candidum GN=BN980_GECA27s00021g PE=4 SV=1
UniRef50_A0A0J9X5S851.311%6100.0Similar to Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter of the major facilitator superfamily n=3 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5S8_GEOCN
A0A1E3PJA3_9ASCO41.983%6052.84e-147SCR1 protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47140 PE=4 SV=1
A0A060T943_BLAAD40.391%6149.89e-140ARAD1D12672p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D12672g PE=4 SV=1
MDR1_CANAL45.860%4716.56e-129Multidrug resistance protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDR1 PE=1 SV=2
Q6C0D8_YARLI39.130%5986.07e-125YALI0F25597p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F25597g PE=4 SV=1
A0A167CAG3_9ASCO43.162%4687.22e-115Flr1p OS=Sugiyamaella lignohabitans GN=FLR1 PE=4 SV=1
FLR1_YEAST40.899%4672.32e-102Fluconazole resistance protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FLR1 PE=1 SV=1
A0A1E4TIX5_9ASCO33.613%4766.45e-66Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14557 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6628

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 598

Detailed signature matches

  1. Family IPR011701
    Major facilitator superfamily
    1. PF07690 (MFS_1)
  2. Domain IPR020846
    Major facilitator superfamily domain
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.12...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Residue annotation

  1. putative substrate...

Protein sequence

>MIA_05930_1
MAPDLIRDSVAGNLLNWLSNGKLFPYPEQRPGFVVPDRYLGLPPQEIMQEKLASLSSSSLQHPPPAAIISSSSQDSLSIS
SNSSSSLRKTQDDLPPRVYEAPDDEEQQLAILPQKSQDPLAQPDDSKSIDHGQFIVVDWYAPDDPDNPQNWSNLKKCWII
FSVAFLTVCMYMGSSIYVSGAAQMMHDLNTSRVMVTLPLTTFIIGYGVAPMVLSPLSEHPPMGRTLLYLLSVAFFCVIQV
PTALVDTIEKIIGLRLLAGMAASPSLSTGGATIGDVVSLDHLPAALVFWAAGALAGPALGPFIGSLFVVKVNWRWTFWFL
CIISGFLLAVISFLLPETNHATILHRRAIRLRKLTGNTNIRSPYEVQEKQSTWQFIKETLWRPIFIAFFEPIVLALNVYI
AFIYIILNSWFESLPIVFNEFYHFTTIEGGLVYLAVLVGGYLGGLCYLLLINRIIKSQHPAIEKFLIPGMVGSFFLPIAL
FIFSWGSSSHTHWMAPVISIAIFTFGALFIFQSTFAYLGRGFYRFLASVFAGNCLMRSIFASIFPIFTPPMYNNLAIKDY
PVAWGGTIWACVGVILIAIPFTIYHFGVQLRGRSKYAN

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane