Protein
MIA_05923_1
Length
834 amino acids
Browser: contig09:717269-720238-
Protein function
EGGNOG: | 0PGJ0 | SEC12 | Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein SAR1. Required for autophagy |
---|---|---|---|
SGD closest match: | S000005309 | SEC12 | Guanine nucleotide-exchange factor SEC12 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_01726_1 | 63.478% | 115 | 1.69e-26 | MCA_01726_1 |
A0A1E3PHK5_9ASCO | 47.059% | 102 | 4.14e-13 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46725 PE=4 SV=1 |
UniRef50_A0A1E3PHK5 | 47.059% | 102 | 1.12e-09 | Uncharacterized protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PHK5_9ASCO |
A0A0J9X2L7_GEOCN | 49.123% | 114 | 6.98e-12 | Similar to Saccharomyces cerevisiae YNR026C SEC12 Guanine nucleotide exchange factor (GEF) OS=Geotrichum candidum GN=BN980_GECA01s03739g PE=4 SV=1 |
A0A167F9I3_9ASCO | 46.729% | 107 | 3.19e-11 | Sar family guanine nucleotide exchange factor SEC12 OS=Sugiyamaella lignohabitans GN=SEC12 PE=4 SV=1 |
A0A060TA45_BLAAD | 53.333% | 105 | 1.08e-10 | ARAD1C42306p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C42306g PE=4 SV=1 |
Q6CHH9_YARLI | 42.056% | 107 | 3.86e-08 | YALI0A08646p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A08646g PE=4 SV=1 |
SEC12_YEAST | 38.835% | 103 | 3.17e-07 | Guanine nucleotide-exchange factor SEC12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC12 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0015
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
834
Detailed signature matches
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Protein sequence
>MIA_05923_1 MTNKDNATIDVKFPVFTAKFLCDERLIIGGGGGEGKNGIKNKISIVDIDFAEPSDNKILRQATEICLHDNEDNPTSLDVT QTGTIFAGVNRASSKVKAKENDHLRVFQIVTESEESVKARQKKAEEEKKKAAEEKKKALEEKLKKKKKAAEEKKKAAEEK KAKEAKKKGKKKGKKDDEKKEKEEEEEEKEEEEEEEEEEEEQEPEVEIFEREESIEQVASKSIFKSGDTEEYQKCTVTNP TSKIVAISNSLSGKKSKLSILKYDPNAPATPPTLVYTISSADELAINDIDISPNGQSIVHITDSTIAISLATSSTILCKA KLPKSETDEIAPAGSIFAKVKFIDNETLIVAANHPKRAGASLIKLAIISNNKKDSLVITDYKKVIDKSSITSLDAVKLTP KIKPAPPKKTEKKVEKKAEKKAEKKAEKKAEKKKGKKGKGKGKKSGKSKKVEKKTEKKDVEEKVEEEVEEEEPEEKIEEQ IEEQIEEEVEKEAEREAEAEKEVDEDDDIELVEKAEAEEAEREYEKESEKSDDKESEKSDEKESEKSDEKESEKDDKEES EKDEKEGSEKKTKQESEKTPEKDTKKETEISEKPEKKTEKSKKSEKSKKKDEPIEIPTFPEVHGFAAFATADLSAYDENE LVFDEEEVDDMDEFDQYDDDPQDEEDPDDDLADYADDEDEEKDEDDEDGDEDDDEDDEDDEDDEDDEDDEDDEDDEDDED DEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDEDDDDDD DDEDDEDDEDDEDDEDDEEDDDDEDDDEEDEDED
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005515 protein binding
Cellular Component
None predicted.