Protein

MIA_05916_1

Length
336 amino acids

Browser: contig09:698126-699241-

Protein function

EGGNOG:0PI5TCKA1casein kinase ii
SGD closest match:S000005587CKA2Casein kinase II subunit alpha'
CGD closest match:CAL0000178518CKA1Casein kinase 2 catalytic subunit

Protein alignments

%idAln lengthE-value
MCA_00483_175.235%3191.17e-172MCA_00483_1
A0A0J9XJC9_GEOCN70.312%3207.80e-162Similar to Saccharomyces cerevisiae YOR061W CKA2 Alpha' catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation OS=Geotrichum candidum GN=BN980_GECA21s01330g PE=3 SV=1
Q6C8U8_YARLI69.620%3162.17e-158YALI0D16863p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D16863g PE=3 SV=1
A0A1E3PNU0_9ASCO66.456%3164.24e-153Casein kinase II OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81701 PE=3 SV=1
UniRef50_Q6BXZ666.458%3191.77e-149DEHA2A13662p n=33 Tax=Eukaryota TaxID=2759 RepID=Q6BXZ6_DEBHA
A0A060TGD1_BLAAD66.144%3197.38e-153ARAD1D22660p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22660g PE=3 SV=1
A0A1D8PUA2_CANAL65.517%3195.17e-148Casein kinase 2 catalytic subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CKA1 PE=3 SV=1
A0A161HHJ2_9ASCO65.031%3265.57e-146Casein kinase 2 catalytic subunit CKA2 OS=Sugiyamaella lignohabitans GN=CKA2 PE=3 SV=1
A0A1E4TLZ5_9ASCO64.000%3251.16e-144Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_92635 PE=3 SV=1
CSK22_YEAST60.377%3182.13e-131Casein kinase II subunit alpha' OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CKA2 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4782

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 336

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd14132 (STKc_CK2_a...)

Residue annotation

  1. CK2 beta interface...
  2. tetramer interface...
  3. allosteric inhibit...
  4. active site cd14132
  5. ATP binding site c...
  6. polypeptide substr...
  7. activation loop (A...

Protein sequence

>MIA_05916_1
MDSKDPRFISRVYADANEKFPQSYWDYEHAAINWGYQEKYEIIKRVGRGKYSEVFESIDIETKELVIIKVLKPVKHKKIK
REIKILSNLEGGPNIISFLNVVHDTESKTTSLVFERVQNIDFRTLYPTFTPYDIKFYMYQLLLALDYAHSMGIMHRDVKP
HNVMIDHEAKRLRLIDWGLAEFYHKGVDYNVRVASRYFKGPELLVEYQRYDYSLDIWSFGAMFASLIFKREPFFHGNSNT
DQLVKIARVLGTSDLYEYLRKYHIKLGSEFDDLGSFARRPWSKFITEANSAFATDVTVDFLDKLLVYDHQKRLTAKEAMA
HPYFDELTPLERQKGK

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.