Protein

MIA_05852_1

Length
835 amino acids

Browser: contig09:519327-521887-

Protein function

EGGNOG:0PIINSPB1rRNA methyltransferase spb1
SGD closest match:S000000559SPB127S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase
CGD closest match:CAL0000201177SPB1AdoMet-dependent rRNA methyltransferase SPB1

Protein alignments

%idAln lengthE-value
MCA_05470_168.258%8380.0MCA_05470_1
A0A167CBA4_9ASCO59.826%5750.0AdoMet-dependent rRNA methyltransferase SPB1 OS=Sugiyamaella lignohabitans GN=SPB1 PE=3 SV=1
UniRef50_A0A167CBA459.826%5750.0AdoMet-dependent rRNA methyltransferase SPB1 n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CBA4_9ASCO
A0A0J9X5H0_GEOCN68.095%4202.01e-180AdoMet-dependent rRNA methyltransferase SPB1 OS=Geotrichum candidum GN=SPB1 PE=3 SV=1
A0A1E3PRG9_9ASCO56.649%5799.62e-177AdoMet-dependent rRNA methyltransferase SPB1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=SPB1 PE=3 SV=1
A0A060TAL0_BLAAD58.767%5191.06e-168AdoMet-dependent rRNA methyltransferase SPB1 OS=Blastobotrys adeninivorans GN=SPB1 PE=3 SV=1
SPB1_YEAST52.159%5793.69e-16127S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPB1 PE=1 SV=2
SPB1_CANAL55.744%5318.39e-160AdoMet-dependent rRNA methyltransferase SPB1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPB1 PE=3 SV=1
SPB1_YARLI59.823%4536.84e-156AdoMet-dependent rRNA methyltransferase SPB1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SPB1 PE=3 SV=1
A0A1E4TBK1_9ASCO61.947%3397.98e-142Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_15225 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0268

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 835

Detailed signature matches

  1. Family IPR015507
    Ribosomal RNA large subunit methyltransferase E
    1. MF_01547 (RNA_methy...)
  2. Family IPR028589
    AdoMet-dependent rRNA methyltransferase, Spb1
    1. MF_03163 (RNA_methy...)
  3. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  4. Domain IPR002877
    Ribosomal RNA methyltransferase FtsJ domain
    1. PF01728 (FtsJ)
  5. Domain IPR024576
    Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381
    1. PF11861 (DUF3381)
  6. Domain IPR012920
    Ribosomal RNA methyltransferase, Spb1, C-terminal
    1. PF07780 (Spb1_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd02440 (AdoMet_MTases)
  4. mobidb-lite (disord...)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MIA_05852_1
MGKAQKKHGKGRLDKYYRTAKEKGYRARSSFKIIQINDKFGHFLEKSRCVIDLCAAPGSWCQVAAERCPANSLIIGVDLD
RIKPIPNVITFQSDITTEHCRSELRAYMKTWKADAVLHDGAPNVGKDWSQDAFTQSELVLQSLKLAIEFLRPNGIFVTKV
FRSKDYNKLMWIFQQFFEKVEATKPPSSRNVSAEIFVVCRNFKAPKKIDPKLLDSSYVFEDIQQVNNESFEKLLNPEKKK
RKREGYEEGDYTQFHEVPVMEYIKTKDPVQLLGTKSAFSFDKKDPELKPVYALESTTPELLECIKDLKVLGRREFRLLLK
WRKEARKAIGLDAKPEAEETQEEEPEVDEETRIDNELDNLKEKVQQKQKREKRKLNEKKQKEIVKMQLDMVSDMRMGTEV
DDQGKSLFDLTAAERTGKVGTLLKGKKALLDSGETRDDLEVDGIEKASDLAQFQYDDRSDAEIIDDMEDEMDAMYEEFKE
RQAQKSSAYRSKKARESGYDDEWYGIKENGSDDDNDDKDGVRLEDDSDSEGFESDEEGYSKNIINTLKPKTTASGLSSKA
ALFFTDPLFRDVDLTASPETSSSSKSDSSKTQDSSETDDGDEVEEKEQGEGDESEDEIDYLSDSGEDQNQEGKEWDEDDD
EEGSPAPEIVTAQAMTIAHDLALGNINKHRLVDEGFNRLAFNDREGLPSWFLEDEEKHNRVLKPVTKEAAEAIKAKLKAL
NARPIKKIAEAKARKQMRRVRRLEKLRKKTDLINEDEALSERDKADEISKLTKKLTASKKSKKSDKPKVKLVVAKGGNRG
LKGRPKGIKGKYKMVDGTLKKEQRALKRIQKSRKK

GO term prediction

Biological Process

GO:0001510 RNA methylation
GO:0006364 rRNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation

Molecular Function

GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity

Cellular Component

GO:0005634 nucleus