Protein

MIA_05851_1

Length
798 amino acids

Browser: contig09:516250-518647-

Protein function

EGGNOG:0PIZRubiquitin carboxyl-terminal hydrolase
SGD closest match:S000005130UBP10Ubiquitin carboxyl-terminal hydrolase 10
CGD closest match:CAL0000187993DOT4Ubiquitin-specific protease

Protein alignments

%idAln lengthE-value
MCA_05469_162.982%3894.64e-174MCA_05469_1
A0A0J9X489_GEOCN47.989%3483.23e-114Similar to Saccharomyces cerevisiae YNL186W UBP10 Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties OS=Geotrichum candidum GN=BN980_GECA02s04536g PE=3 SV=1
A0A060TA42_BLAAD48.295%3521.92e-116ARAD1D20394p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D20394g PE=3 SV=1
UniRef50_A0A060TA4248.295%3524.74e-113ARAD1D20394p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060TA42_BLAAD
A0A1E3PFP8_9ASCO44.571%3501.95e-104Cysteine proteinase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_12288 PE=4 SV=1
A0A1D8PLU4_CANAL42.559%3835.77e-89Ubiquitin-specific protease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DOT4 PE=3 SV=1
Q6C7Z0_YARLI43.109%3411.58e-89YALI0D24211p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D24211g PE=3 SV=1
A0A167CB96_9ASCO52.381%1895.87e-55Ubp10p OS=Sugiyamaella lignohabitans GN=UBP10 PE=3 SV=1
A0A1E4TC85_9ASCO32.849%3447.00e-54Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138945 PE=3 SV=1
UBP10_YEAST46.875%1926.84e-47Ubiquitin carboxyl-terminal hydrolase 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBP10 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2462

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 798

Detailed signature matches

  1. Domain IPR028889
    Ubiquitin specific protease domain
    1. PS50235 (USP_3)
  2. Domain IPR001394
    Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    1. PF00443 (UCH)
  3. SITE IPR018200
    Ubiquitin specific protease, conserved site
    1. PS00973 (USP_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.90.70.10
  2. SSF54001 (Cysteine ...)
  3. mobidb-lite (disord...)

Protein sequence

>MIA_05851_1
MAASSVVLPKRTSDVMEQLKGARLDFVSAKFPEAVSTRPASYIHIKPKIPQGEDSEDEALLKSDESDESCTASDESKRNT
ESEQSDVDMSEFEDAIDFSGPVQKKETHKKKRAITASKKVESEDSQSRSSNETSEEEEESAESDDVDSEDDDEDDHDDED
DTQNRNAADDKSSIEKTEPAESTATVTKEVPNNFEYMTQKEKILSRIQKEDEYFRMVNKKYTFTEPNTDPKDRGSHGEAS
RIMKTFPKNMSPPRGLINNGVTCYMNSAVQALIHVPAMARYLTSVNKGDYKDTISPRSVTRDLAHLFARMTDGSNGHKSI
SPKQLIRRLDEINPLMSEWNQEDAHEYFMSLIGRLQEDSVPKGQKLKSSILHEMFGGTFLQTVVCQECKNKSETHQDFFD
IQVSIDKHELKVMGKSTLRGSLRQYFDQSFIKKSKSEGYDCEKCKKKTSASTIQRIEEAPEYLILSIKRYEYTSNRNSSQ
KIKQHLAIAPTIELTQYAVNEEPMRYQLVAFTVHEGRSASSGHYVAYCMQPDKTWALYDDDYVHQLSANQVYRSKDDVYF
LVYTRVRATLREGEIREATPPVFMNGLVGANDEDAEGDEDDEAGDENTDKLSSVDNSSSSSKKTKKMMKKKKGEISGLSK
KHSGSPPKGHRFPVPRKNSGDSISSASSVRSSGKIKKYGKRHLRKGSFGSAVQSLAPVNNLKKSRSAPAGMNELGSQKDG
EEAASKHLFKSNHHHTSGKNAFSKLAEKFRLNNAGKKRSVAATVNSKEELNRPGSSHSDSSQKKRKLDKDIDDIFNRL

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination

Molecular Function

GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component

None predicted.