Protein

MIA_05787_1

Length
708 amino acids

Browser: contig09:321564-323691+

Protein function

EGGNOG:0PG9WATG7E1-like activating enzyme involved in cytoplasm to vacuole transport (Cvt) and autophagy (By similarity)
SGD closest match:S000001214ATG7Ubiquitin-like modifier-activating enzyme ATG7
CGD closest match:CAL0000178896APG7Ubiquitin-like modifier-activating enzyme ATG7

Protein alignments

%idAln lengthE-value
MCA_05942_162.465%7220.0MCA_05942_1
A0A0J9X9J9_GEOCN51.863%6710.0Similar to Saccharomyces cerevisiae YHR171W ATG7 Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes OS=Geotrichum candidum GN=BN980_GECA06s02122g PE=4 SV=1
UniRef50_A0A0J9X9J951.863%6710.0Similar to Saccharomyces cerevisiae YHR171W ATG7 Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X9J9_GEOCN
A0A060T8J7_BLAAD51.982%6810.0ARAD1C37598p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37598g PE=4 SV=1
A0A1E3PLZ6_9ASCO47.184%6578.83e-172Autophagy-related protein 7 (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8780 PE=4 SV=1
ATG7_CANAL44.211%6655.41e-167Ubiquitin-like modifier-activating enzyme ATG7 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APG7 PE=3 SV=2
ATG7_YARLI43.093%6664.24e-163Ubiquitin-like modifier-activating enzyme ATG7 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ATG7 PE=3 SV=1
A0A1E4THN2_9ASCO44.055%6569.71e-160Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14939 PE=4 SV=1
ATG7_YEAST43.459%6652.01e-158Ubiquitin-like modifier-activating enzyme ATG7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG7 PE=1 SV=1
A0A167F2I2_9ASCO61.022%3138.17e-124Atg7p OS=Sugiyamaella lignohabitans GN=ATG7 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0141

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 708

Detailed signature matches

  1. Family IPR006285
    Ubiquitin-like modifier-activating enzyme Atg7
    1. TIGR01381
  2. Domain IPR032197
    Ubiquitin-like modifier-activating enzyme Atg7, N-terminal
    1. PF16420 (ATG7_N)
  3. Domain IPR000594
    THIF-type NAD/FAD binding fold
    1. PF00899 (ThiF)
    2. SSF69572 (Activatin...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd01486 (Apg7)
  3. mobidb-lite (disord...)

Residue annotation

  1. putative ATP bindi...

Protein sequence

>MIA_05787_1
MDNLLNTQDLNQQTPSSSGSETSQHVVSSLKFATFRSFVDSAFFHELSAHKLDHIKLDETPIPVLGSYSEAPSTAVSYAS
FSVTRTSLKATDYTPLTYTAPPAVGAPGRLLDLNTIESFKSYDRAGLLRTRMQEIASAVLSGGALQDPSLLCTFQILMFS
DLKKYNFYYWFAFPAPLIDWRAEKVETSFKVTNEVMAAIEGWRSEVDPRQWGFFLLKKDLSSENEGGWKVGQLNEYSSFL
RLEAEEVYLAFVDPSPHELVAGWPLRNLLLLAFHYNLFKKFPNLKVLAYRGRPGANKPQSFVLSGLESPLDDKDLTAYLE
AVPKATGWERLPTTNKLAPKYTNLGALIDPVQLADQAVDLNLKLMKWRVAPDLNLDIVKNTRCLLLGAGTLGSYIARGLL
GWGVRKITLVDSGRVSYSNPVRQPLYTFKDCADGGKPKAECAAAALREIYPSVDASGIQLEIPMAGHAVHDEPSQKKDYE
KLEELIKSHDVVFLLMDSRESRWLPTVMCAAQSKLVINAALGFDSYVVMRHGIVAEGAPTPNLGCYFCNDVVAPLDSLSN
RTLDQMCTVTRPGVAMLASANAVELLVSVLQHPSKGLVPSTEYSGQDTQPSETPSANGAFGNRIPHQIRGFLGSFDSLKV
TGAAYPSCSACSAPVREEWATRGWEFVKDALNNPKYVEELSGLAEVQRKTEELNLGDEDDGDDWALSD

GO term prediction

Biological Process

GO:0006914 autophagy

Molecular Function

GO:0008641 small protein activating enzyme activity

Cellular Component

GO:0005737 cytoplasm