Protein
MCA_05942_1
Length
719 amino acids
Gene name: ATG7
Description: Ubiquitin-like modifier-activating enzyme ATG7
Browser: contigD:2819931-2822091-
RNA-seq: read pairs 3295, FPKM 56.5, percentile rank 68.0% (100% = highest expression)
Protein function
| Annotation: | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7 | |
|---|---|---|---|
| KEGG: | K08337 | ATG7 | ubiquitin-like modifier-activating enzyme ATG7 |
| EGGNOG: | 0PG9W | ATG7 | E1-like activating enzyme involved in cytoplasm to vacuole transport (Cvt) and autophagy (By similarity) |
| SGD closest match: | S000001214 | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7 |
| CGD closest match: | CAL0000178896 | APG7 | Ubiquitin-like modifier-activating enzyme ATG7 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05787_1 | 62.33% | 722 | 0.0 | MIA_05787_1 |
| A0A0J9X9J9_GEOCN | 50.36% | 701 | 0.0 | Similar to Saccharomyces cerevisiae YHR171W ATG7 Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes OS=Geotrichum candidum GN=BN980_GECA06s02122g PE=4 SV=1 |
| UniRef50_A0A0J9X9J9 | 50.36% | 701 | 0.0 | Similar to Saccharomyces cerevisiae YHR171W ATG7 Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X9J9_GEOCN |
| A0A060T8J7_BLAAD | 46.42% | 698 | 0.0 | ARAD1C37598p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37598g PE=4 SV=1 |
| ATG7_CANAL | 40.42% | 720 | 1e-159 | Ubiquitin-like modifier-activating enzyme ATG7 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APG7 PE=3 SV=2 |
| A0A1E3PLZ6_9ASCO | 42.59% | 688 | 1e-158 | Autophagy-related protein 7 (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8780 PE=4 SV=1 |
| ATG7_YEAST | 40.06% | 714 | 2e-154 | Ubiquitin-like modifier-activating enzyme ATG7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG7 PE=1 SV=1 |
| A0A1E4THN2_9ASCO | 39.42% | 690 | 1e-151 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14939 PE=4 SV=1 |
| ATG7_YARLI | 52.28% | 394 | 4e-133 | Ubiquitin-like modifier-activating enzyme ATG7 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ATG7 PE=3 SV=1 |
| A0A167F2I2_9ASCO | 60.61% | 297 | 5e-109 | Atg7p OS=Sugiyamaella lignohabitans GN=ATG7 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0054
Protein family membership
- Ubiquitin-like modifier-activating enzyme Atg7 (IPR006285)
Domains and repeats
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Domain
1
100
200
300
400
500
600
719
Detailed signature matches
-
-
PF16420 (ATG7_N)
-
no IPR
Unintegrated signatures
-
-
cd01486 (Apg7)
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mobidb-lite (disord...)
Residue annotation
-
putative ATP bindi...
Protein sequence
>MCA_05942_1 MTSEPPQQSIKFAPFTSFVDSAFFHELSARKLNDIKLDESQIPVLGSYSLGQPSSSFASFSVSKSSFFTDNYEPYQYTSP PSYVAHGSVLDLNTIESFKSHDRSAMIKEGLKSTVNAIISGEALQDPSLLSTFQILMYSDLKKFNFYYWFAFPVAMVDWT SDNEFSPFTVTPELHSTIEEWRKANAPSQWGFFLLKQNKADSSSSQSWSVACLKEYNELFSSSDEPTCEYYLAFADPSPH ELIPGWPLRPLLLLAYYYKLFDKYPKLKVLAYRGGKVNNGSYIIPHVSVASNGNEMLEKLFKQEGFSYSEIKATGWERIP TTRKLGPKHTNLGALIDPVQLADQAVDLNLKLMKWRIAPDLDLDVIKNSKCLLLGAGTLGSYIARALMGWGVRKITFVDN GTVSYSNPVRQPLYNFEDCKAGGKPKAECAANALKVIYPSMEAEGYQLEIPMAGHAIRDEESQKRDYDNLEKLIREHDVV FLLMDSRESRWLPTVMCSSLSKIVINAALGFDSFVVMRHGISSSSSSSSSVDNNNNNNDEDDKNSPHLGCYFCNDVVAPL DSLSNRTLDQMCTVTRPGVAMLASANAVELLVSLLQHPMKGLAPPPPTPNNNNNSNEEEQIQSKEAAAKAAFGWTIPHQI RGFLSSFDNIKVTGPAYNLCSACSLPIRKEWELRGWEFVKDALNNPKYLEELSGLSEIQKLTEEMAIGDGDEDDWALSD
GO term prediction
Biological Process
GO:0006914 autophagy
Molecular Function
GO:0008641 small protein activating enzyme activity
Cellular Component
GO:0005737 cytoplasm