Protein

MIA_05751_1

Length
1,282 amino acids

Browser: contig09:229646-233540-

Protein function

EGGNOG:0PFRVECM16RNA helicase
SGD closest match:S000004735ECM16Probable ATP-dependent RNA helicase DHR1
CGD closest match:CAL0000195316orf19.2090ATP-dependent RNA helicase

Protein alignments

%idAln lengthE-value
MCA_00243_174.601%9410.0MCA_00243_1
A0A0J9XA79_GEOCN68.657%9380.0Similar to Saccharomyces cerevisiae YMR128W ECM16 Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP OS=Geotrichum candidum GN=BN980_GECA07s03541g PE=4 SV=1
A0A1E3PK94_9ASCO65.770%9290.0p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_34104 PE=4 SV=1
A0A161HLG4_9ASCO64.409%9300.0Ecm16p OS=Sugiyamaella lignohabitans GN=ECM16 PE=4 SV=1
A0A060T2C7_BLAAD60.365%9310.0ARAD1C27764p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C27764g PE=4 SV=1
Q6C7N7_YARLI57.463%9380.0YALI0D26620p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26620g PE=4 SV=1
UniRef50_Q6C7N757.463%9380.0YALI0D26620p n=7 Tax=Saccharomycetales TaxID=4892 RepID=Q6C7N7_YARLI
DHR1_YEAST55.213%9400.0Probable ATP-dependent RNA helicase DHR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM16 PE=1 SV=1
A0A1D8PG31_CANAL55.484%9300.0ATP-dependent RNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2090 PE=4 SV=1
A0A1E4TLI0_9ASCO52.189%8910.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22192 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1676

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1282

Detailed signature matches

  1. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  5. Domain IPR007502
    Helicase-associated domain
    1. SM00847 (ha2_5)
    2. PF04408 (HA2)
  6. Domain IPR011709
    Domain of unknown function DUF1605
    1. PF07717 (OB_NTP_bind)
  7. SITE IPR002464
    DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    1. PS00690 (DEAH_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00046 (DEXDc)
  4. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...

Protein sequence

>MIA_05751_1
MGTYRKRFNEKARTGMLAKNEKLRKVRQRRFLQQPDGTENQQDHDGREENEDDEDNFDPNAEILLPMTDAEKLERKRKMQ
EQLTSKQESSLSRKKRKRLEKYIHQEKQVDKEEKKVLFEKLKQSKINTSALKSMKTLGVGNETKKELITEALKQERQGIV
NDKISDLLYREREIKNWEDDEEMRQFGAAPIPAFKEREAEDEDNESGASDDDLPKVSGIIDQRPRSNEGFGFTGLKKIPK
TPKPETKSYTWRTKLALQKARKHKIDLAEIDGVTSSEDEDDDEDESDNSDEESGEEDSDENEDDGEVWNGFSDEAETAEK
TEAGEDSLEDNQEAESAEDSDEKSGSEAESSNEDDSDEEDSDIEINIEKPSKGKEFLEWAKKQNEPEQERIETPIYKGEY
KPVERPEDKESLPAEMLIKSKDPNRKSYFVDVQRPDEIQEVRMKLPVVAEEQRIMEAIHNNDAVVICGETGSGKTTQVPQ
FLFEAGYGSPNSTTPGMIGITQPRRVAAVSMAKRVGQELGNMGHKVAYQIRFDATVKEDTSVKFMTDGVLLRELSNDFTL
SKYSALIIDEAHERNVNTDILIGVLTRVMRLRNSNPDQYKPLKLIIMSATLRVSDFAENKALFATPPPILKVDARQFPVS
VHFNRRTPYNYLDEIFRKTKKIHQRLPRGGILIFLTGQNEITTMVKRLRKAFPLKKKEQQEESTAKVIISSKETTTEAED
IDFGIDVNNAEADDFDENLEEEEEEEEGFEETLEEGQDENDPLYVLPLYSLLPTAEQMKVFQPPPPGSRLCVIATNVAET
SLTIPGIRYVVDAGRAKERVYDEATNVQKFIVDWISKASAQQRAGRAGRTEAGHCYRIYSSAVYENDFEQFSKPEILRMP
IEGLVLQMKSMGIDKIVNFPFPTPPERSALKKGLKLLNYLGAVDEKERLTALGKSMSLFPLSPRFAKMLIIGNQFECLPY
IVAIVAGLSVGDPFLQQHEVGIAPEAKEEGEEEEDKQEESIEEKERKRKLRTEYFKVQGRFSSLDTNSDALKLLSAIAAY
GWSKAHEDFADKHFLRYKIMEEIHKLRKQIAYIVSVNTRIDSIDATTTKLTAKLKPPSATQIKAIKQMITAGFIDQIAVR
ADVVATDIPLRSKTRIISFPYFTLFPSTLRKSAKEEVDPYVYIHPSSVLNMAGSGEVPPEYLVYNTLQLSQNSSSDKVRM
KVLTNVTPKQLANVGRDTALITYSKPIGVPKYLDANMTKRECILVPRMGAAIGTGGVGWDLPPCKAIQVKNGIHWVNESL
KY

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding

Cellular Component

None predicted.