Protein

MCA_00243_1

Length
1,344 amino acids

Gene name: ECM16

Description: Probable ATP-dependent RNA helicase DHR1; Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP

Browser: contigA:746532-750631-

RNA-seq: read pairs 1009, FPKM 9.3, percentile rank 24.8% (100% = highest expression)

Protein function

Annotation:ECM16Probable ATP-dependent RNA helicase DHR1; Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP
KEGG:K14780DHX37 ATP-dependent RNA helicase DHX37/DHR1 [EC:3.6.4.13]
EGGNOG:0PFRVECM16RNA helicase
SGD closest match:S000004735ECM16Probable ATP-dependent RNA helicase DHR1
CGD closest match:CAL0000195316orf19.2090ATP-dependent RNA helicase

Protein alignments

%idAln lengthE-value
MIA_05751_174.60%9410.0MIA_05751_1
A0A0J9XA79_GEOCN64.65%9590.0Similar to Saccharomyces cerevisiae YMR128W ECM16 Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP OS=Geotrichum candidum GN=BN980_GECA07s03541g PE=4 SV=1
A0A161HLG4_9ASCO62.50%9520.0Ecm16p OS=Sugiyamaella lignohabitans GN=ECM16 PE=4 SV=1
A0A1E3PK94_9ASCO61.96%9410.0p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_34104 PE=4 SV=1
A0A060T2C7_BLAAD59.13%9470.0ARAD1C27764p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C27764g PE=4 SV=1
Q6C7N7_YARLI56.05%9580.0YALI0D26620p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26620g PE=4 SV=1
UniRef50_Q6C7N756.05%9580.0YALI0D26620p n=7 Tax=Saccharomycetales TaxID=4892 RepID=Q6C7N7_YARLI
A0A1D8PG31_CANAL55.32%9020.0ATP-dependent RNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2090 PE=4 SV=1
DHR1_YEAST52.28%9660.0Probable ATP-dependent RNA helicase DHR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM16 PE=1 SV=1
A0A1E4TLI0_9ASCO49.06%9070.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22192 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0774

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1344

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  5. Domain IPR007502
    Helicase-associated domain
    1. SM00847 (ha2_5)
    2. PF04408 (HA2)
  6. Domain IPR011709
    Domain of unknown function DUF1605
    1. PF07717 (OB_NTP_bind)
  7. SITE IPR002464
    DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    1. PS00690 (DEAH_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00046 (DEXDc)
  4. cd00079 (HELICc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MCA_00243_1
MGTYRKRFNEKAKTGMLAKHEKLRRARQKRFLQQPDGTEKNELENEIQKEEEFDPNAEILLPMTESEKLEHKKKLQEQLR
KPEESSMSRKKRKRLEKYIEKQIDKEEKKVLFEKLKQTKIDTTVLKSMKTLGVAHETKKDKIAEAIKLEQKGISNEETQR
LLYAEHEVKDWQEDEEMVQAFSKPTEEAQESDQESDKEKDEHFSTFIDNRPRSTGNNNGFGFQGLKKIPKIEKKSYTWRT
KLALKKAKKHGIDLAAIDGETDDSEESEEDSEEESEEEPEEESEEESEEDAGPQRKKFKITTTKKSGRKESDSASDKDGE
EEEEEIWEGFSDEPKIESNSDSDNNSDSKDKNNVDAEEDEAEDSEEDDDQEEEEEDNDNDDDDDDDDDDDDDDDDDDDED
DESSKKSKGKEFAEWAKTMNDQGYEKYETPIYKGEYTPLDRAEDKEELPAEMTMPSKDPNRKAYFVEVERDEEIQASRIK
LPVVGEEQRIMEAIFNNDAVIICGETGSGKTTQVPQFLFEAGYGSPNSNTPGMIGITQPRRVAAVSMAKRVGQELGNHGH
KVAHQIRFDANVTEDTSIKFMTDGVLLRELSQDFVLSKYSALIIDEAHERNVNTDILIGVLTRVLRLRNGGSNNRYKPLK
LIIMSATLRVSDFSENKALFLTPPPILKVDARQFPVSVHFNRRTPFDYLDEIFRKTKKIHQRLPRGGILIFLTGQNEITA
LCKKLRRAFPFKKQTTTKNIKGLKESKEDGDDKDDTEKRVVVSSKDTTTEIEDIDFGVERGDIDAEVDDFDEELEEEEEE
GFDETLEEGQDMNDPLYVLPLYSLLPTSEQMKVFQDPPAGARLCVVATNVAETSLTIPGIRYVVDSGRAKERIYDEDTNV
QKFEINWISKASAEQRAGRAGRTGPGHCYRIFSSAVYDRDFEQFSKPEILRMPIEGLVLQMKSMGIDKIVNFPFPTPPEK
SSLERGLKLLNYLGAIDSSEKLTTLGKSMSFFPLSPRFAKMLIIGNQFDCLPYIVAIVAGLSVGEPFLQPHEIGINANNK
DDSDDEQEEEDDVETKEFKRQLRSNYHKTQAKFSALDPKSDALKLLSAICSYDWAKNREDFANQHFLRYKIMEEIRKLRQ
QIAYIVAVNTKIDAIDATTHKLSTKLPPPNTTQVKAIKQMITSGFVDQIAVRADIITTELKLKPKTRIISYPYSTLFPSS
VRRGNKNWNLREELDRYVYIHPSSVLNMMGSNDDLPPDYLVFNALQMSQNKNTTDAKSKVRMKLLTNVTAKQLANVAKST
ALITYSKPIGTPKYLDPAMTKRECYLVPRMGADIGTGGVGWDLPVVKAIQYKKQGTWVNESVKY

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding

Cellular Component

None predicted.