Protein

MIA_05711_1

Length
599 amino acids

Browser: contig09:122337-124184+

Protein function

EGGNOG:0PFSRFG02056.1Dihydroxy-acid dehydratase
SGD closest match:S000003777ILV3Dihydroxy-acid dehydratase, mitochondrial
CGD closest match:CAL0000180914ILV3Dihydroxy-acid dehydratase

Protein alignments

%idAln lengthE-value
MCA_05850_182.203%5900.0MCA_05850_1
A0A0J9XAB3_GEOCN78.866%5820.0Similar to Saccharomyces cerevisiae YJR016C ILV3 Dihydroxyacid dehydratase OS=Geotrichum candidum GN=BN980_GECA05s06643g PE=3 SV=1
Q5AJY2_CANAL72.366%5790.0Dihydroxy-acid dehydratase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ILV3 PE=3 SV=1
A0A1E3PFY4_9ASCO69.360%5940.0Dihydroxy-acid dehydratase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47535 PE=3 SV=1
A0A161HI10_9ASCO71.226%5630.0Dihydroxy-acid dehydratase ILV3 OS=Sugiyamaella lignohabitans GN=ILV3 PE=3 SV=1
ILV3_YEAST69.430%5790.0Dihydroxy-acid dehydratase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ILV3 PE=1 SV=2
UniRef50_P3952269.430%5790.0Dihydroxy-acid dehydratase, mitochondrial n=275 Tax=cellular organisms TaxID=131567 RepID=ILV3_YEAST
A0A060SXB1_BLAAD69.097%5760.0ARAD1A07964p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A07964g PE=3 SV=1
Q6CAY2_YARLI71.528%5760.0YALI0C23408p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23408g PE=3 SV=2
A0A1E4TC72_9ASCO65.404%5810.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138909 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9592

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 599

Detailed signature matches

  1. Family IPR000581
    Dihydroxy-acid/6-phosphogluconate dehydratase
    1. PF00920 (ILVD_EDD)
  2. Family IPR004404
    Dihydroxy-acid dehydratase
    1. TIGR00110
    2. MF_00012 (IlvD)
  3. Domain IPR015928
    Aconitase/3-isopropylmalate dehydratase, swivel
    1. SSF52016 (LeuD/IlvD...)
  4. SITE IPR020558
    Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site
    1. PS00886 (ILVD_EDD_1)
    2. PS00887 (ILVD_EDD_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF143975 (IlvD/EDD...)

Protein sequence

>MIA_05711_1
MLAFQRAKSNQMLGKRLARSFQTGAIRCKDNQLNKVSATITKALDQGPSQAMLYGTGFKKADFDKAQVGISSVWWTGNTC
NMHLLDLNFKVKEGVEKAGLKGMQFNTIGVSDGMSNGTEGMRYSLQSRDIIADSIETMMMAQYYDANISIPGCDKNMPGV
LMAMGRVNRPSIMVYGGTIDPGVGTCGKFKDQPLDIISVFQSYGQILAKEISEEEREDVIEHACPGEGACGGMYTANTMA
SAAELLGMSLPGSSSNPARSAAKYQECIEAGEAIKNLLRIGLTPRDIMTKTAFENAITYIIVTGGSTNAVLHMIAIAKSV
GVDLTVDDFQKISDKTPFLADFKPSGKYAMADLPKIGGTPAVVKFLLEEGLIDGSTITCTGKTLAENVEKLPGFPAGQKI
IRPLSNPIKPTGHLQILRGTLAPGSAVAKITGKEGTYFKGKARVYNDEVEFIHSLERGEIKKGEKTVAVIRYEGPKGGPG
MPEMLKPSSALMGYGLGKDVALLTDGRFSGGSHGFLIGHIVPEAAEGGPIALVEDGDEIVIDSDNNKIDLNVDEAVLAER
KSKWTPPKPRYTRGTLAKYSRLVSDASHGCVTDLARDEY

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009082 branched-chain amino acid biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004160 dihydroxy-acid dehydratase activity

Cellular Component

None predicted.