Protein

MCA_05850_1

Length
595 amino acids

Gene name: ILV3

Description: Dihydroxy-acid dehydratase, mitochondrial

Browser: contigD:2536947-2538907-

RNA-seq: read pairs 6869, FPKM 142.4, percentile rank 84.3% (100% = highest expression)

Protein function

Annotation:ILV3Dihydroxy-acid dehydratase, mitochondrial
KEGG:K01687ilvD dihydroxy-acid dehydratase [EC:4.2.1.9]
EGGNOG:0PFSRFG02056.1Dihydroxy-acid dehydratase
SGD closest match:S000003777ILV3Dihydroxy-acid dehydratase, mitochondrial
CGD closest match:CAL0000180914ILV3Dihydroxy-acid dehydratase

Protein alignments

%idAln lengthE-value
MIA_05711_182.20%5900.0MIA_05711_1
A0A0J9XAB3_GEOCN78.01%5820.0Similar to Saccharomyces cerevisiae YJR016C ILV3 Dihydroxyacid dehydratase OS=Geotrichum candidum GN=BN980_GECA05s06643g PE=3 SV=1
Q5AJY2_CANAL71.86%5970.0Dihydroxy-acid dehydratase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ILV3 PE=3 SV=1
A0A1E3PFY4_9ASCO72.05%5760.0Dihydroxy-acid dehydratase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47535 PE=3 SV=1
A0A161HI10_9ASCO72.60%5620.0Dihydroxy-acid dehydratase ILV3 OS=Sugiyamaella lignohabitans GN=ILV3 PE=3 SV=1
A0A060SXB1_BLAAD71.75%5770.0ARAD1A07964p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A07964g PE=3 SV=1
ILV3_YEAST70.26%5850.0Dihydroxy-acid dehydratase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ILV3 PE=1 SV=2
UniRef50_P3952270.26%5850.0Dihydroxy-acid dehydratase, mitochondrial n=275 Tax=cellular organisms TaxID=131567 RepID=ILV3_YEAST
Q6CAY2_YARLI72.01%5610.0YALI0C23408p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23408g PE=3 SV=2
A0A1E4TC72_9ASCO66.90%5800.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138909 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9955
Predicted cleavage: 31

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 595

Detailed signature matches

  1. Family IPR000581
    Dihydroxy-acid/6-phosphogluconate dehydratase
    1. PF00920 (ILVD_EDD)
  2. Family IPR004404
    Dihydroxy-acid dehydratase
    1. TIGR00110
    2. MF_00012 (IlvD)
  3. Domain IPR015928
    Aconitase/3-isopropylmalate dehydratase, swivel
    1. SSF52016 (LeuD/IlvD...)
  4. SITE IPR020558
    Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site
    1. PS00886 (ILVD_EDD_1)
    2. PS00887 (ILVD_EDD_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF143975 (IlvD/EDD...)

Protein sequence

>MCA_05850_1
MLSTVQRAQSCKLLTKNLFRSFQTSAIARNEVKLNKVSSQLTESIDQGPSQAMLYGTGFKKEDFQKAQVGVGSVWWSGNS
CNMHLLDLNFRVTKGVEAAGLKGMQFNTIGVSDGMSNGTEGMRYSLQSREIIADSFETIMMGQFYDANIAIPGCDKNMPG
VLMAMGRVNRPSIMVYGGTINAGVGTCGKFAGKQLDIISAFQSYGQYLANEITEEERDDVIQHACPGEGACGGMYTANTM
ASAAEVLGMSLPGSSSNPANSEAKYKECFDSGEAIKNLLKLDLKPSDIMTKKAFENAITYIIATGGSTNAVLHLIAIAKS
VNIDLTVDDFQRISDKTPLLADFKPSGKFVMADLPSIGGTPAAIKFLLKEGLLDGSTYTVTGKTLAQNVEEFPDFPADQK
IFRPLSNPIKTTGHIQILRGSLAPGSAVAKITGKEGTYFKGSARVFGNEVDFIHALERGEIKKGEKTVVVIRYEGPKGGP
GMPEMLKPSSALMGYGLGKDVALLTDGRFSGGSHGFLIGHIVPEAAVGGPIALVEDGDTIVIDSDKNIIDLLVPEDVLAE
RKKKWTPPAPKYTRGTLSKYARLVSDASHGCITDL

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009082 branched-chain amino acid biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004160 dihydroxy-acid dehydratase activity

Cellular Component

None predicted.