Protein

MIA_05571_1

Length
720 amino acids


Browser: contig08:842866-845029+

Protein function

EGGNOG:0PJN7FG04264.1transcription initiation factor IIF subunit alpha
SGD closest match:S000003418TFG1Transcription initiation factor IIF subunit alpha
CGD closest match:CAL0000187824TFG1Transcription factor IIF subunit

Protein alignments

%idAln lengthE-value
MCA_02036_156.114%5971.97e-163MCA_02036_1
A0A0J9XIP5_GEOCN51.429%4552.93e-115Similar to Saccharomyces cerevisiae YGR186W TFG1 TFIIF (Transcription Factor II) largest subunit, involved in both transcription initiation and elongation of RNA polymerase II OS=Geotrichum candidum GN=BN980_GECA20s00505g PE=4 SV=1
UniRef50_A0A0J9XIP551.429%4555.98e-112Similar to Saccharomyces cerevisiae YGR186W TFG1 TFIIF (Transcription Factor II) largest subunit, involved in both transcription initiation and elongation of RNA polymerase II n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIP5_GEOCN
A0A1E3PMD4_9ASCO43.993%5661.48e-102Rap30/74 interaction domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82364 PE=4 SV=1
A0A167D3X1_9ASCO44.970%5071.50e-101Transcription factor IIF subunit TFG1 OS=Sugiyamaella lignohabitans GN=TFG1 PE=4 SV=1
Q6C1W7_YARLI39.691%5822.81e-84YALI0F12815p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12815g PE=4 SV=1
A0A060TEF7_BLAAD47.253%2737.72e-78ARAD1D14828p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14828g PE=4 SV=1
Q5AMR1_CANAL44.840%2816.22e-71Transcription factor IIF subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TFG1 PE=4 SV=1
A0A1E4TJV6_9ASCO38.172%3722.19e-51Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_626 PE=4 SV=1
T2FA_YEAST57.258%1248.01e-40Transcription initiation factor IIF subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TFG1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9806
Predicted cleavage: 22

Protein family membership

Domains and repeats

1 100 200 300 400 500 600 720

Detailed signature matches

    1. PF05793 (TFIIF_alpha)
    1. SSF50916 (Rap30/74 ...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_05571_1
MSNPLIQPKRRFARNADPLRRPSRPVIKKPAVGKPTATKQKLLPNSQPSTSILASAIVAGSDSLKPSDKTQYREYNLNAC
NEDDIKDLRYHLMRFHSKTEVNPVGTFTKPIRLHRKDPRNMQNQLTLAELEERNKRLGITTSIPKHLLAEAAAAETKANS
GDENIKTENGEPKTSDTANGKDDAKQKGKTTSEEADMSLIAPDGGARRGKSHLFQKKTKQVVLGDANARKLRYEEYYPWI
LEDFDGKNTWVGNYEAGQTDAYVLFVFDNDGFKMVPAEKWYKMTPRNKYATLTSEEAEKQMEKGELPNRWVMKYFGNEEG
ATTKHPTNMRRRFRTTDSNTVDEMRRDDDGNDIDFDEEFADDEEAPIMEGNEDEVKEVENKIKKEHQSAKISALFDEQEN
EEEDEENRKVDKQGKHMIKYLRSREKNINYETDDDSNPYATEESSEEEEEIDNPASLGGAIKGPNGTEIKKEPGTEAIKT
ESVTIKTEEGAEGTPAASVPGEEKPKKKLKDKKLKEKKKKKGLKKHHNLPRGMVILNLPPAKLAQFQSDLWNPGLKRRRA
ELSDGEESGVKHKVKKLKTKDKSNAGGANKNTATATQASVHPTNSLVNNPAAANTAAAAPSTTNGQSTSPGNRLSTSPAA
SAAEGSPSPVSGSTASNQVDLITEEEVKQVVRSQRLNAREILAVFKNRYRKKPENLKLLMQHLKHVAKINEGYLVLRDNV

GO term prediction

Biological Process

GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter

Molecular Function

GO:0003677 DNA binding
GO:0003824 catalytic activity

Cellular Component

GO:0005634 nucleus